SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nlz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 12 ALA A  51
LEU A 361
ALA A 122
LEU A 142
ILE A  52
 None
 1.26A 1g5yB-2nlzA:
undetectable		 1g5yB-2nlzA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 8 GLU A 213
GLU A 150
ALA A 145
THR A  56
 None
 0.78A 1ie4B-2nlzA:
undetectable
1ie4D-2nlzA:
undetectable		 1ie4B-2nlzA:
15.04
1ie4D-2nlzA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 12 ALA A  34
GLY A 527
THR A 528
LEU A  41
ALA A  21
 None
 1.44A 1jipA-2nlzA:
0.6		 1jipA-2nlzA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 12 GLY A 512
ASP A 467
GLY A 526
ILE A 515
VAL A 451
 None
 0.94A 1k6cB-2nlzA:
undetectable		 1k6cB-2nlzA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 12 ALA A 525
GLY A 526
GLY A 527
ASP A 518
GLY A 368
 None
 0.92A 1sqfA-2nlzA:
undetectable		 1sqfA-2nlzA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 5 LEU A 208
ALA A  57
LEU A 142
SER A 141
 None
 1.02A 1tt6B-2nlzA:
undetectable		 1tt6B-2nlzA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 LEU A 208
ALA A  57
LEU A 142
SER A 141
 None
 1.03A 1tz8C-2nlzA:
undetectable
1tz8D-2nlzA:
undetectable		 1tz8C-2nlzA:
15.28
1tz8D-2nlzA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 7 TYR A 378
GLY A 441
THR A 420
TYR A 418
 None
 1.09A 2g70B-2nlzA:
undetectable		 2g70B-2nlzA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 5 LEU A 328
LEU A 277
MET A 304
THR A 316
 None
 1.35A 2oaxD-2nlzA:
undetectable		 2oaxD-2nlzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 5 LEU A 208
GLN A 375
THR A  56
THR A 390
 None
 1.06A 2zj0B-2nlzA:
undetectable		 2zj0B-2nlzA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 ALA A  74
ALA A  55
THR A  56
ASN A  66
 None
 0.87A 3b6hA-2nlzA:
undetectable		 3b6hA-2nlzA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 ALA A  74
ALA A  55
THR A  56
ASN A  66
 None
 0.85A 3b6hB-2nlzA:
1.2		 3b6hB-2nlzA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 8 GLU A  62
SER A  29
GLN A  30
VAL A 195
 None
 1.18A 3b9lA-2nlzA:
undetectable		 3b9lA-2nlzA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 7 LEU A 208
ALA A  57
LEU A 142
SER A 141
 None
 0.95A 3d2tA-2nlzA:
undetectable		 3d2tA-2nlzA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 12 LEU A 239
ALA A 230
GLY A 236
LYS A 234
ILE A 228
 None
 1.31A 3gyqA-2nlzA:
undetectable
3gyqB-2nlzA:
undetectable		 3gyqA-2nlzA:
18.35
3gyqB-2nlzA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA303_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 4 GLN A 472
GLN A 446
GLY A 447
HIS A 448
 None
 1.11A 3huoA-2nlzA:
0.0		 3huoA-2nlzA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 9 VAL A  26
ILE A  40
ALA A  50
ALA A  55
THR A  56
 None
 1.07A 3mdtA-2nlzA:
undetectable		 3mdtA-2nlzA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 9 VAL A  26
ILE A  40
ALA A  50
ALA A  57
THR A  56
 None
 1.04A 3mdvA-2nlzA:
undetectable		 3mdvA-2nlzA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 12 VAL A  26
ILE A  40
ALA A  50
ALA A  55
THR A  56
 None
 0.93A 3mdvB-2nlzA:
undetectable		 3mdvB-2nlzA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		6 / 12 ALA A  51
THR A  54
ALA A  53
ALA A  50
VAL A 371
ALA A  72
 None
 1.35A 3mg0Y-2nlzA:
3.3
3mg0Z-2nlzA:
undetectable		 3mg0Y-2nlzA:
16.79
3mg0Z-2nlzA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 4 SER A 372
GLY A 447
GLU A 482
 None
 0.67A 3raeA-2nlzA:
undetectable
3raeC-2nlzA:
undetectable		 3raeA-2nlzA:
22.20
3raeC-2nlzA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 12 ARG A 470
GLN A 444
GLY A 437
PHE A 373
GLU A 529
 None
 1.08A 3t7sA-2nlzA:
undetectable		 3t7sA-2nlzA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 LEU A 208
ALA A  57
LEU A 142
SER A 141
 None
 1.04A 4d7bB-2nlzA:
undetectable		 4d7bB-2nlzA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 7 ILE A 456
ARG A 260
VAL A 283
MET A 304
 None
 1.35A 4f4dA-2nlzA:
undetectable		 4f4dA-2nlzA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 6 LEU A 208
ALA A  57
LEU A 142
SER A 141
THR A  54
 None
 1.24A 4i89A-2nlzA:
undetectable		 4i89A-2nlzA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 10 VAL A  26
ILE A  40
ALA A  50
ALA A  55
THR A  56
 None
 1.09A 4j14A-2nlzA:
1.6		 4j14A-2nlzA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 4 SER A 372
GLY A 447
GLU A 482
 None
 0.58A 4juoA-2nlzA:
undetectable
4juoC-2nlzA:
undetectable		 4juoA-2nlzA:
22.20
4juoC-2nlzA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 10 TYR A 360
VAL A 451
GLY A 424
PHE A 436
GLY A 512
 None
 1.16A 4mmcA-2nlzA:
0.0		 4mmcA-2nlzA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 LEU A 208
ALA A  57
LEU A 142
SER A 141
 None
 1.01A 4pwjA-2nlzA:
undetectable		 4pwjA-2nlzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 7 LEU A 208
ALA A  57
LEU A 142
SER A 141
 None
 1.03A 4pwjB-2nlzA:
undetectable		 4pwjB-2nlzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 10 LEU A 138
LEU A 142
SER A 210
ALA A 125
ILE A  52
 None
 0.99A 4xj7C-2nlzA:
undetectable
4xj7D-2nlzA:
undetectable		 4xj7C-2nlzA:
20.19
4xj7D-2nlzA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 10 LEU A 138
LEU A 142
SER A 210
ALA A 125
PRO A 123
 None
 1.17A 4xj7C-2nlzA:
undetectable
4xj7D-2nlzA:
undetectable		 4xj7C-2nlzA:
20.19
4xj7D-2nlzA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_DIFA601_1
(SERUM ALBUMIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 9 LEU A 524
ASP A 365
ASN A 369
ALA A 364
VAL A 371
 None
 1.45A 4zbrA-2nlzA:
0.0		 4zbrA-2nlzA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 6 LEU A 208
ALA A  57
LEU A 142
SER A 141
THR A  54
 None
 1.21A 5bojA-2nlzA:
undetectable		 5bojA-2nlzA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 7 LEU A 208
ALA A  57
LEU A 142
SER A 141
 None
 0.99A 5bojB-2nlzA:
undetectable		 5bojB-2nlzA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 ARG A  16
ARG A 511
THR A  64
GLU A  62
 None
 1.08A 5btcA-2nlzA:
undetectable
5btcC-2nlzA:
undetectable
5btcD-2nlzA:
undetectable		 5btcA-2nlzA:
24.80
5btcC-2nlzA:
24.80
5btcD-2nlzA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 ARG A 511
THR A  64
GLU A  62
ARG A  16
 None
 1.10A 5btcA-2nlzA:
undetectable
5btcB-2nlzA:
undetectable
5btcC-2nlzA:
undetectable		 5btcA-2nlzA:
24.80
5btcB-2nlzA:
19.41
5btcC-2nlzA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 12 GLY A 424
GLY A 437
ILE A 267
LEU A 426
LEU A  75
 None
 1.04A 5bw4B-2nlzA:
undetectable		 5bw4B-2nlzA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 6 LEU A 208
ALA A  57
LEU A 142
SER A 141
THR A  54
 None
 1.24A 5l4iA-2nlzA:
undetectable		 5l4iA-2nlzA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 LEU A 208
ALA A  57
LEU A 142
SER A 141
 None
 1.00A 5l4iB-2nlzA:
undetectable		 5l4iB-2nlzA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 4 GLN A 535
THR A  28
LEU A  41
LEU A  38
 None
 1.28A 5m5kB-2nlzA:
undetectable		 5m5kB-2nlzA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 3 VAL A 481
VAL A 502
GLN A 491
 None
 0.68A 5qguA-2nlzA:
undetectable		 5qguA-2nlzA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 3 VAL A 481
VAL A 502
GLN A 491
 None
 0.71A 5qgwA-2nlzA:
undetectable		 5qgwA-2nlzA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 3 VAL A 481
VAL A 502
GLN A 491
 None
 0.72A 5qgxA-2nlzA:
undetectable		 5qgxA-2nlzA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 3 VAL A 481
VAL A 502
GLN A 491
 None
 0.72A 5qh4A-2nlzA:
undetectable		 5qh4A-2nlzA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 3 VAL A 481
VAL A 502
GLN A 491
 None
 0.69A 5qh9A-2nlzA:
undetectable		 5qh9A-2nlzA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 3 VAL A 481
VAL A 502
GLN A 491
 None
 0.71A 5qheA-2nlzA:
undetectable		 5qheA-2nlzA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 3 VAL A 481
VAL A 502
GLN A 491
 None
 0.69A 5qhfA-2nlzA:
undetectable		 5qhfA-2nlzA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 8 SER A  65
GLN A  30
MET A 439
THR A 532
 None
 1.47A 5u6nA-2nlzA:
undetectable		 5u6nA-2nlzA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 SER A  65
GLN A  30
MET A 439
THR A 532
 None
 1.45A 5u6nB-2nlzA:
undetectable		 5u6nB-2nlzA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 7 ASP A 226
ALA A 230
LYS A 241
LEU A 244
 None
 0.89A 6ci6A-2nlzA:
undetectable		 6ci6A-2nlzA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		3 / 3 LEU A 411
SER A 402
PHE A 401
 None
 0.61A 6fgcA-2nlzA:
undetectable		 6fgcA-2nlzA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 6 ARG A 221
ALA A 245
LEU A 244
ALA A 225
 None
 1.13A 6fosB-2nlzA:
undetectable		 6fosB-2nlzA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		4 / 5 THR A 427
THR A  78
HIS A  83
GLY A 424
 None
 1.21A 6gbnC-2nlzA:
undetectable		 6gbnC-2nlzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 2nlz CEPHALOSPORIN
ACYLASE
(Bacillus
halodurans) 		5 / 12 ILE A  40
VAL A  26
THR A 363
PHE A 373
PRO A 423
 None
 1.09A 6hlpA-2nlzA:
undetectable		 6hlpA-2nlzA:
21.54