SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nm0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 2nm0 PROBABLE
3-OXACYL-(ACYL-CARRI
ER-PROTEIN)
REDUCTASE
(Streptomyces
coelicolor) 		4 / 4 VAL A  55
LEU A 115
ILE A 163
LEU A 154
 None
 0.92A 2byoA-2nm0A:
undetectable		 2byoA-2nm0A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2nm0 PROBABLE
3-OXACYL-(ACYL-CARRI
ER-PROTEIN)
REDUCTASE
(Streptomyces
coelicolor) 		5 / 12 ILE A  18
ALA A  17
GLY A  13
ILE A 204
GLY A   9
 None
 0.88A 2qe6A-2nm0A:
undetectable		 2qe6A-2nm0A:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2nm0 PROBABLE
3-OXACYL-(ACYL-CARRI
ER-PROTEIN)
REDUCTASE
(Streptomyces
coelicolor) 		5 / 12 ILE A  18
ALA A  17
GLY A  13
ILE A 204
GLY A   9
 None
 0.93A 2qe6B-2nm0A:
undetectable		 2qe6B-2nm0A:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 2nm0 PROBABLE
3-OXACYL-(ACYL-CARRI
ER-PROTEIN)
REDUCTASE
(Streptomyces
coelicolor) 		5 / 12 THR A 207
LEU A 211
ILE A 125
THR A 103
VAL A 107
 None
 1.31A 3a51B-2nm0A:
undetectable		 3a51B-2nm0A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 2nm0 PROBABLE
3-OXACYL-(ACYL-CARRI
ER-PROTEIN)
REDUCTASE
(Streptomyces
coelicolor) 		5 / 12 VAL A 226
VAL A 193
VAL A 208
ILE A 125
THR A 207
 None
 1.21A 3dl9A-2nm0A:
undetectable		 3dl9A-2nm0A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2nm0 PROBABLE
3-OXACYL-(ACYL-CARRI
ER-PROTEIN)
REDUCTASE
(Streptomyces
coelicolor) 		5 / 12 GLY A   9
SER A  35
ASP A  48
ILE A  49
THR A  50
 None
 0.89A 3iv6A-2nm0A:
5.8		 3iv6A-2nm0A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2nm0 PROBABLE
3-OXACYL-(ACYL-CARRI
ER-PROTEIN)
REDUCTASE
(Streptomyces
coelicolor) 		5 / 10 VAL A  29
ALA A 212
ARG A 209
VAL A 208
ILE A  73
 None
 1.44A 3retA-2nm0A:
undetectable
3retB-2nm0A:
undetectable		 3retA-2nm0A:
17.77
3retB-2nm0A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_B_SALB201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2nm0 PROBABLE
3-OXACYL-(ACYL-CARRI
ER-PROTEIN)
REDUCTASE
(Streptomyces
coelicolor) 		5 / 9 VAL A  29
ALA A 212
ARG A 209
VAL A 208
ILE A  73
 None
 1.42A 3retB-2nm0A:
0.5		 3retB-2nm0A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 2nm0 PROBABLE
3-OXACYL-(ACYL-CARRI
ER-PROTEIN)
REDUCTASE
(Streptomyces
coelicolor) 		4 / 6 SER A 143
GLY A  15
ARG A  12
GLY A   9
 None
 0.75A 5cdpA-2nm0A:
undetectable
5cdpB-2nm0A:
3.3		 5cdpA-2nm0A:
20.84
5cdpB-2nm0A:
21.74