SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nn5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1B2I_A_AMHA84_1 (PROTEIN (PLASMINOGEN))	2nn5	HYPOTHETICAL PROTEIN EF_2215 (Enterococcus faecalis)	4 / 7	ASP A 117 GLU A 104 TRP A 81 PHE A 57	None	1.36A	1b2iA-2nn5A: undetectable	1b2iA-2nn5A: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KXH_A_ACRA598_2 (ALPHA-AMYLASE)	2nn5	HYPOTHETICAL PROTEIN EF_2215 (Enterococcus faecalis)	3 / 3	TRP A 28 TYR A 30 LEU A 100	None	1.02A	1kxhA-2nn5A: undetectable	1kxhA-2nn5A: 16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JFA_B_RALB600_2 (ESTROGEN RECEPTOR)	2nn5	HYPOTHETICAL PROTEIN EF_2215 (Enterococcus faecalis)	4 / 4	LEU A 155 THR A 156 ILE A 147 HIS A 150	EDO A 301 ( 4.3A) None None None	1.22A	2jfaB-2nn5A: undetectable	2jfaB-2nn5A: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E9X_A_NIMA1_1 (LACTOTRANSFERRIN')	2nn5	HYPOTHETICAL PROTEIN EF_2215 (Enterococcus faecalis)	4 / 4	GLU A 104 GLY A 15 THR A 16 GLU A 17	None	1.14A	3e9xA-2nn5A: undetectable	3e9xA-2nn5A: 16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K8M_B_ACRB820_1 (ALPHA-AMYLASE, SUSG)	2nn5	HYPOTHETICAL PROTEIN EF_2215 (Enterococcus faecalis)	4 / 7	TYR A 71 GLU A 48 LEU A 77 TRP A 28	None	1.26A	3k8mB-2nn5A: undetectable	3k8mB-2nn5A: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A81_A_DXCA1161_0 (MAJOR POLLEN ALLERGEN BET V 1-A)	2nn5	HYPOTHETICAL PROTEIN EF_2215 (Enterococcus faecalis)	5 / 12	GLY A 120 ASP A 117 ILE A 86 VAL A 79 LEU A 125	None	0.95A	4a81A-2nn5A: 10.3	4a81A-2nn5A: 23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DRJ_A_RAPA201_2 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4 SERINE/THREONINE-PRO TEIN KINASE MTOR)	2nn5	HYPOTHETICAL PROTEIN EF_2215 (Enterococcus faecalis)	4 / 8	LEU A 152 PHE A 144 ASP A 117 TYR A 151	None	1.00A	4drjB-2nn5A: undetectable	4drjB-2nn5A: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M10_A_NCAA603_0 (CYCLOHEXANONE MONOOXYGENASE FROM THERMOCRISPUM MUNICIPALE)	2nn5	HYPOTHETICAL PROTEIN EF_2215 (Enterococcus faecalis)	4 / 5	LEU A 37 PHE A 88 LEU A 128 TRP A 55	None	1.46A	5m10A-2nn5A: undetectable	5m10A-2nn5A: 16.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1B2I_A_AMHA84_1","PROTEIN (PLASMINOGEN)","2nn5","HYPOTHETICAL PROTEIN EF_2215","Enterococcus faecalis",4,"ASP A 117;GLU A 104;TRP A  81;PHE A  57","None","1.36A","1b2iA-2nn5A:undetectable","1b2iA-2nn5A:18.89"],["1KXH_A_ACRA598_2","ALPHA-AMYLASE","2nn5","HYPOTHETICAL PROTEIN EF_2215","Enterococcus faecalis",3,"TRP A  28;TYR A  30;LEU A 100","None","1.02A","1kxhA-2nn5A:undetectable","1kxhA-2nn5A:16.45"],["2JFA_B_RALB600_2","ESTROGEN RECEPTOR","2nn5","HYPOTHETICAL PROTEIN EF_2215","Enterococcus faecalis",4,"LEU A 155;THR A 156;ILE A 147;HIS A 150","EDO A 301 ( 4.3A);None;None;None","1.22A","2jfaB-2nn5A:undetectable","2jfaB-2nn5A:25.00"],["3E9X_A_NIMA1_1","LACTOTRANSFERRIN'","2nn5","HYPOTHETICAL PROTEIN EF_2215","Enterococcus faecalis",4,"GLU A 104;GLY A  15;THR A  16;GLU A  17","None","1.14A","3e9xA-2nn5A:undetectable","3e9xA-2nn5A:16.62"],["3K8M_B_ACRB820_1","ALPHA-AMYLASE, SUSG","2nn5","HYPOTHETICAL PROTEIN EF_2215","Enterococcus faecalis",4,"TYR A  71;GLU A  48;LEU A  77;TRP A  28","None","1.26A","3k8mB-2nn5A:undetectable","3k8mB-2nn5A:13.45"],["4A81_A_DXCA1161_0","MAJOR POLLEN ALLERGEN BET V 1-A","2nn5","HYPOTHETICAL PROTEIN EF_2215","Enterococcus faecalis",5,"GLY A 120;ASP A 117;ILE A  86;VAL A  79;LEU A 125","None","0.95A","4a81A-2nn5A:10.3","4a81A-2nn5A:23.81"],["4DRJ_A_RAPA201_2","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4;SERINE\/THREONINE-PROTEIN KINASE MTOR","2nn5","HYPOTHETICAL PROTEIN EF_2215","Enterococcus faecalis",4,"LEU A 152;PHE A 144;ASP A 117;TYR A 151","None","1.00A","4drjB-2nn5A:undetectable","4drjB-2nn5A:17.32"],["5M10_A_NCAA603_0","CYCLOHEXANONE MONOOXYGENASE FROM THERMOCRISPUM MUNICIPALE","2nn5","HYPOTHETICAL PROTEIN EF_2215","Enterococcus faecalis",4,"LEU A  37;PHE A  88;LEU A 128;TRP A  55","None","1.46A","5m10A-2nn5A:undetectable","5m10A-2nn5A:16.91"]]