SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nn6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 9 GLU A 211
ASP A 142
ILE A 145
ILE A 146
THR A  53
 None
 1.34A 1aj6A-2nn6A:
undetectable		 1aj6A-2nn6A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 12 GLU A 211
ASP A 142
ILE A 145
ILE A 146
THR A  53
 None
 1.40A 1kijA-2nn6A:
undetectable		 1kijA-2nn6A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		5 / 11 ALA F 214
LEU F 122
GLU F 121
ALA F 125
LEU F 226
 None
 1.19A 1mjlA-2nn6F:
undetectable
1mjlB-2nn6F:
undetectable		 1mjlA-2nn6F:
17.58
1mjlB-2nn6F:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		4 / 4 VAL F  62
ALA F 148
LEU F 126
PHE F 100
 None
 1.02A 1q97B-2nn6F:
undetectable		 1q97B-2nn6F:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
(Homo
sapiens) 		4 / 7 CYH C 233
SER C 116
PHE C 108
LEU C 248
 None
 1.04A 1qcaA-2nn6C:
undetectable		 1qcaA-2nn6C:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 12 ILE A 223
LEU A 248
LYS A 252
ARG A 229
ILE A 231
 None
 1.08A 1rb2B-2nn6A:
undetectable		 1rb2B-2nn6A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
EXOSOME COMPONENT 6
(Homo
sapiens) 		5 / 10 PHE F 105
ALA C 155
ILE C 109
LEU C 156
ASP C  84
 None
 1.09A 1yi4A-2nn6F:
undetectable		 1yi4A-2nn6F:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		4 / 5 LEU F 158
LEU F 122
LEU F 126
CYH F  64
 None
 0.96A 2ab2B-2nn6F:
undetectable		 2ab2B-2nn6F:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
(Homo
sapiens) 		5 / 12 LEU C 142
ASP C  84
VAL C  83
PHE C 154
CYH C 152
 None
 1.34A 2g70A-2nn6C:
undetectable		 2g70A-2nn6C:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
(Homo
sapiens) 		5 / 12 LEU C 142
ASP C  84
VAL C  83
PHE C 154
CYH C 152
 None
 1.30A 2g70B-2nn6C:
undetectable		 2g70B-2nn6C:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
(Homo
sapiens) 		5 / 10 GLU C 215
ASN C 147
THR C 204
LEU C 248
LEU C 243
 None
 1.50A 2ha6A-2nn6C:
undetectable		 2ha6A-2nn6C:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 12 GLU A 211
LEU A 138
PHE A  90
GLN A  95
ALA A  87
 None
 1.30A 2noaA-2nn6A:
undetectable		 2noaA-2nn6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
EXOSOME COMPONENT 6
(Homo
sapiens;
Homo
sapiens) 		4 / 6 THR F 200
ARG F  37
THR F  60
ASP C  46
 None
 1.18A 2okcA-2nn6F:
undetectable		 2okcA-2nn6F:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
EXOSOME COMPONENT 6
(Homo
sapiens;
Homo
sapiens) 		4 / 6 THR F 200
ARG F  37
THR F  60
ASP C  46
 None
 1.21A 2okcB-2nn6F:
undetectable		 2okcB-2nn6F:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		4 / 6 ASP A 208
ARG A  27
ILE A 261
SER A 150
 None
 1.31A 3ckzA-2nn6A:
undetectable		 3ckzA-2nn6A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
EXOSOME COMPONENT 6
(Homo
sapiens) 		5 / 9 ILE C  59
GLU F 152
LEU F 151
LYS F  61
TYR F  54
 None
 1.23A 3f78A-2nn6C:
undetectable		 3f78A-2nn6C:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		4 / 4 ARG A  33
ASP A 147
ASP A 208
PRO A 209
 None
 1.43A 3fgrB-2nn6A:
undetectable		 3fgrB-2nn6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		5 / 12 GLU F 118
GLY F 227
GLU F 204
ASP F 153
GLY F 155
 None
 1.15A 3jzjA-2nn6F:
undetectable		 3jzjA-2nn6F:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		5 / 12 VAL F  62
LEU F  55
LEU F 150
GLY F 182
ALA F 159
 None
 0.88A 3kk6A-2nn6F:
undetectable		 3kk6A-2nn6F:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		3 / 3 ARG A  23
ASP A 147
GLN A 235
 None
 0.80A 3lcvB-2nn6A:
undetectable		 3lcvB-2nn6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 10 ILE A 154
ILE A 265
ILE A 187
SER A 113
HIS A 228
 None
 1.28A 3o1cA-2nn6A:
undetectable		 3o1cA-2nn6A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 10 ILE A 154
ILE A 265
ILE A 187
SER A 113
HIS A 228
 None
 1.27A 3o1xA-2nn6A:
undetectable		 3o1xA-2nn6A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 12 GLY A  40
VAL A 275
ASP A 272
ILE A 151
GLY A  57
 None
 0.97A 3sufD-2nn6A:
undetectable		 3sufD-2nn6A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
EXOSOME COMPONENT 6
(Homo
sapiens;
Homo
sapiens) 		3 / 3 SER C  48
PHE F 105
LYS C  63
 None
 0.70A 3u88A-2nn6C:
undetectable		 3u88A-2nn6C:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 11 SER A 150
ASN A 210
GLU A 211
ASP A 208
HIS A 141
 None
 1.41A 4fewE-2nn6A:
0.0
4fewF-2nn6A:
0.0		 4fewE-2nn6A:
21.34
4fewF-2nn6A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		4 / 8 LEU A  98
PRO A 209
GLY A 219
MET A 217
 None
 0.89A 4klrB-2nn6A:
undetectable		 4klrB-2nn6A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		4 / 8 LYS A 257
ILE A  35
ALA A 148
LEU A  50
 None
 0.62A 4qrcA-2nn6A:
undetectable		 4qrcA-2nn6A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		5 / 9 ALA F 164
THR F 163
ALA F 165
ALA F  43
ASP F 171
 None
 1.23A 4qvnK-2nn6F:
undetectable
4qvnL-2nn6F:
undetectable		 4qvnK-2nn6F:
20.74
4qvnL-2nn6F:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		5 / 9 ALA F 164
THR F 163
ALA F 165
ALA F  43
ASP F 171
 None
 1.23A 4qvnY-2nn6F:
undetectable
4qvnZ-2nn6F:
undetectable		 4qvnY-2nn6F:
20.74
4qvnZ-2nn6F:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		5 / 9 ALA F 157
SER F 156
ALA F 161
ALA F 164
ALA F  57
 None
 1.32A 4twdA-2nn6F:
undetectable
4twdB-2nn6F:
undetectable
4twdC-2nn6F:
undetectable
4twdD-2nn6F:
undetectable
4twdE-2nn6F:
undetectable		 4twdA-2nn6F:
21.60
4twdB-2nn6F:
21.60
4twdC-2nn6F:
21.60
4twdD-2nn6F:
21.60
4twdE-2nn6F:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 11 ASN A 144
GLU A 211
ASP A 142
ILE A 146
THR A  53
 None
 1.41A 4urnA-2nn6A:
undetectable		 4urnA-2nn6A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 11 ASN A 144
GLU A 211
ASP A 142
ILE A 146
THR A  53
 None
 1.44A 4urnB-2nn6A:
undetectable		 4urnB-2nn6A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 11 ASN A 144
GLU A 211
ASP A 142
ILE A 146
THR A  53
 None
 1.43A 4urnC-2nn6A:
undetectable		 4urnC-2nn6A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1
(Homo
sapiens) 		5 / 12 GLU A 211
ASP A 142
ILE A 145
ILE A 146
THR A  53
 None
 1.38A 4uroD-2nn6A:
undetectable		 4uroD-2nn6A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
(Homo
sapiens) 		3 / 3 SER C 197
ALA C 195
VAL C 194
 None
 0.66A 4x20C-2nn6C:
undetectable		 4x20C-2nn6C:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
(Homo
sapiens) 		4 / 5 GLU C 214
ALA C 199
GLU C 215
ASN C 147
 None
 1.44A 5dwkC-2nn6C:
undetectable		 5dwkC-2nn6C:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
EXOSOME COMPONENT 6
(Homo
sapiens) 		5 / 8 ALA F 164
LEU F 149
LEU F 151
LEU F  46
LEU C  88
 None
 1.24A 5jqbA-2nn6F:
undetectable
5jqbB-2nn6F:
undetectable		 5jqbA-2nn6F:
20.29
5jqbB-2nn6F:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
(Homo
sapiens) 		4 / 5 HIS C 259
LEU C 235
CYH C 234
ASP C 150
 None
 1.38A 5vcvA-2nn6C:
undetectable		 5vcvA-2nn6C:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		4 / 5 LEU F 179
ALA F 166
LEU F 167
LEU F 130
 None
 0.85A 5vkqA-2nn6F:
undetectable
5vkqD-2nn6F:
undetectable		 5vkqA-2nn6F:
10.91
5vkqD-2nn6F:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		4 / 5 LEU F 130
LEU F 179
ALA F 166
LEU F 167
 None
 0.85A 5vkqA-2nn6F:
undetectable
5vkqB-2nn6F:
undetectable		 5vkqA-2nn6F:
10.91
5vkqB-2nn6F:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		4 / 5 LEU F 130
LEU F 179
ALA F 166
LEU F 167
 None
 0.83A 5vkqB-2nn6F:
undetectable
5vkqC-2nn6F:
undetectable		 5vkqB-2nn6F:
10.91
5vkqC-2nn6F:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2nn6 EXOSOME COMPONENT 6
(Homo
sapiens) 		4 / 5 LEU F 130
LEU F 179
ALA F 166
LEU F 167
 None
 0.87A 5vkqC-2nn6F:
undetectable
5vkqD-2nn6F:
undetectable		 5vkqC-2nn6F:
10.91
5vkqD-2nn6F:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43
(Homo
sapiens) 		3 / 3 GLY C  54
ASP C 145
ILE C 148
 None
 0.54A 6dgxB-2nn6C:
undetectable		 6dgxB-2nn6C:
14.08