SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nnf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEI_A_SHHA2004_1 (HDAC6 PROTEIN)	2nnf	SULFUR COVALENTLY-BINDING PROTEIN (Chlorobium limicola)	5 / 12	PRO A 69 SER A 60 PHE A 62 PHE A 20 ASP A 13	None	1.27A	5eeiA-2nnfA: undetectable	5eeiA-2nnfA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF8_A_LBHA2004_1 (HDAC6 PROTEIN)	2nnf	SULFUR COVALENTLY-BINDING PROTEIN (Chlorobium limicola)	5 / 12	PRO A 69 SER A 60 PHE A 62 PHE A 20 ASP A 13	None	1.23A	5ef8A-2nnfA: undetectable	5ef8A-2nnfA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J20_A_GBQA1201_0 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	2nnf	SULFUR COVALENTLY-BINDING PROTEIN (Chlorobium limicola)	5 / 12	ASN A 58 VAL A 49 ILE A 25 ILE A 33 PHE A 62	None	1.06A	6j20A-2nnfA: undetectable	6j20A-2nnfA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J21_A_GBQA1201_0 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	2nnf	SULFUR COVALENTLY-BINDING PROTEIN (Chlorobium limicola)	5 / 12	ASN A 58 ILE A 31 VAL A 49 ILE A 25 PHE A 62	None	1.29A	6j21A-2nnfA: undetectable	6j21A-2nnfA: 14.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5EEI_A_SHHA2004_1","HDAC6 PROTEIN","2nnf","SULFUR COVALENTLY-BINDING PROTEIN","Chlorobium limicola",5,"PRO A  69;SER A  60;PHE A  62;PHE A  20;ASP A  13","None","1.27A","5eeiA-2nnfA:undetectable","5eeiA-2nnfA:16.29"],["5EF8_A_LBHA2004_1","HDAC6 PROTEIN","2nnf","SULFUR COVALENTLY-BINDING PROTEIN","Chlorobium limicola",5,"PRO A  69;SER A  60;PHE A  62;PHE A  20;ASP A  13","None","1.23A","5ef8A-2nnfA:undetectable","5ef8A-2nnfA:16.29"],["6J20_A_GBQA1201_0","SUBSTANCE-P RECEPTOR,ENDOLYSIN","2nnf","SULFUR COVALENTLY-BINDING PROTEIN","Chlorobium limicola",5,"ASN A  58;VAL A  49;ILE A  25;ILE A  33;PHE A  62","None","1.06A","6j20A-2nnfA:undetectable","6j20A-2nnfA:14.12"],["6J21_A_GBQA1201_0","SUBSTANCE-P RECEPTOR,ENDOLYSIN","2nnf","SULFUR COVALENTLY-BINDING PROTEIN","Chlorobium limicola",5,"ASN A  58;ILE A  31;VAL A  49;ILE A  25;PHE A  62","None","1.29A","6j21A-2nnfA:undetectable","6j21A-2nnfA:14.12"]]