SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.78A 1a7yA-2nnuA:
undetectable		 1a7yA-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.72A 1a7yB-2nnuA:
undetectable		 1a7yB-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.72A 1i3wE-2nnuA:
undetectable		 1i3wE-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.82A 1i3wE-2nnuA:
undetectable		 1i3wE-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.78A 1i3wF-2nnuA:
undetectable		 1i3wF-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.77A 1i3wG-2nnuA:
undetectable		 1i3wG-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.84A 1i3wG-2nnuA:
undetectable		 1i3wG-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.81A 1i3wH-2nnuA:
undetectable		 1i3wH-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.79A 1mnvD-2nnuA:
undetectable		 1mnvD-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.75A 1ovfB-2nnuA:
undetectable		 1ovfB-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.78A 1qfiA-2nnuA:
undetectable		 1qfiA-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.71A 1qfiB-2nnuA:
undetectable		 1qfiB-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2nnu BROMODOMAIN-CONTAINI
NG PROTEIN 4
REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9;
Homo
sapiens) 		3 / 3 LYS B1343
ILE A  73
THR A  81
 None
 0.76A 1rx3A-2nnuB:
undetectable		 1rx3A-2nnuB:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.80A 1unjF-2nnuA:
undetectable		 1unjF-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.72A 1unjF-2nnuA:
undetectable		 1unjF-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.80A 1unjL-2nnuA:
undetectable		 1unjL-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.80A 1unjL-2nnuA:
undetectable		 1unjL-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.84A 1unjR-2nnuA:
undetectable		 1unjR-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.79A 1unjR-2nnuA:
undetectable		 1unjR-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.80A 1unjW-2nnuA:
undetectable		 1unjW-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.81A 1unjX-2nnuA:
undetectable		 1unjX-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.77A 1unjX-2nnuA:
undetectable		 1unjX-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.82A 1unmE-2nnuA:
undetectable		 1unmE-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.77A 1unmE-2nnuA:
undetectable		 1unmE-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 104
PRO A 106
THR A 107
 None
 0.81A 1unmF-2nnuA:
undetectable		 1unmF-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 THR A 107
THR A 104
PRO A 106
 None
 0.83A 1unmF-2nnuA:
undetectable		 1unmF-2nnuA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		4 / 6 THR A 146
VAL A 145
GLU A  90
SER A  85
 None
 1.18A 3b6rB-2nnuA:
undetectable		 3b6rB-2nnuA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 2nnu BROMODOMAIN-CONTAINI
NG PROTEIN 4
REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9;
Homo
sapiens) 		5 / 12 ALA A  69
LEU A  38
SER B1355
ILE B1356
LEU A   4
 None
 1.45A 3ia4A-2nnuA:
undetectable		 3ia4A-2nnuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 GLY A 156
TRP A 184
VAL A 119
 None
 0.52A 3n62B-2nnuA:
undetectable		 3n62B-2nnuA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 GLY A 156
TRP A 184
VAL A 119
 None
 0.55A 3n65B-2nnuA:
undetectable		 3n65B-2nnuA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 GLY A 156
TRP A 184
VAL A 119
 None
 0.53A 3n66B-2nnuA:
undetectable		 3n66B-2nnuA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 2nnu BROMODOMAIN-CONTAINI
NG PROTEIN 4
REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9;
Homo
sapiens) 		3 / 3 LYS B1343
ILE A  73
THR A  81
 None
 0.81A 4gh8A-2nnuB:
undetectable		 4gh8A-2nnuB:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 LYS A  14
HIS A  35
HIS A  18
 None
 1.29A 5oexA-2nnuA:
undetectable		 5oexA-2nnuA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 LYS A  14
HIS A  35
HIS A  18
 None
 1.29A 5oexB-2nnuA:
undetectable		 5oexB-2nnuA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 LYS A  14
HIS A  35
HIS A  18
 None
 1.29A 5oexC-2nnuA:
undetectable		 5oexC-2nnuA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 LYS A  14
HIS A  35
HIS A  18
 None
 1.28A 5oexD-2nnuA:
undetectable		 5oexD-2nnuA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		3 / 3 GLY A 156
TRP A 184
VAL A 119
 None
 0.54A 5vuoB-2nnuA:
undetectable		 5vuoB-2nnuA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		 2nnu REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
9) 		4 / 5 TYR A 167
ASN A 133
TYR A 131
PHE A 171
 None
 1.49A 6h3dA-2nnuA:
undetectable		 6h3dA-2nnuA:
18.16