SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 2nog ISWI PROTEIN
(Xenopus
laevis) 		3 / 3 ALA A 869
VAL A 864
TRP A 829
 None
 0.88A 1kqeA-2nogA:
undetectable
1kqeE-2nogA:
undetectable		 1kqeA-2nogA:
6.38
1kqeE-2nogA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 2nog ISWI PROTEIN
(Xenopus
laevis) 		3 / 3 ALA A 869
VAL A 864
TRP A 829
 None
 0.87A 1kqeB-2nogA:
undetectable
1kqeD-2nogA:
undetectable		 1kqeB-2nogA:
6.38
1kqeD-2nogA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 2nog ISWI PROTEIN
(Xenopus
laevis) 		3 / 3 TRP A 829
ALA A 869
VAL A 864
 None
 0.89A 1kqeB-2nogA:
undetectable
1kqeD-2nogA:
undetectable		 1kqeB-2nogA:
6.38
1kqeD-2nogA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 2nog ISWI PROTEIN
(Xenopus
laevis) 		3 / 3 TRP A 829
ALA A 869
VAL A 864
 None
 0.86A 1kqeA-2nogA:
undetectable
1kqeE-2nogA:
undetectable		 1kqeA-2nogA:
6.38
1kqeE-2nogA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 2nog ISWI PROTEIN
(Xenopus
laevis) 		4 / 6 ASP A 833
PHE A 759
TYR A 867
LEU A 878
 None
 1.10A 2w98A-2nogA:
undetectable
2w98B-2nogA:
undetectable		 2w98A-2nogA:
18.21
2w98B-2nogA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2nog ISWI PROTEIN
(Xenopus
laevis) 		4 / 5 THR A 884
ILE A 888
GLU A 892
PHE A 837
 None
 1.45A 4acbC-2nogA:
undetectable		 4acbC-2nogA:
15.73