SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2noq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 2noq 60S RIBOSOMAL
PROTEIN L11-B
(Saccharomyces
cerevisiae) 		3 / 3 GLU H  87
LEU H  83
LEU H  18
 None
 0.76A 3ohtA-2noqH:
undetectable		 3ohtA-2noqH:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 2noq 60S RIBOSOMAL
PROTEIN L11-B
(Saccharomyces
cerevisiae) 		3 / 3 GLU H  87
LEU H  83
LEU H  18
 None
 0.72A 3ohtB-2noqH:
undetectable		 3ohtB-2noqH:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2noq 60S RIBOSOMAL
PROTEIN L11-B
(Saccharomyces
cerevisiae) 		4 / 8 GLY H 134
ALA H 135
GLY H 148
THR H 153
 None
 0.71A 3so9A-2noqH:
undetectable		 3so9A-2noqH:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 2noq 60S RIBOSOMAL
PROTEIN L11-B
(Saccharomyces
cerevisiae) 		3 / 3 ARG H  91
ASP H 157
ASP H  10
 None
 0.83A 4kicB-2noqH:
undetectable		 4kicB-2noqH:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2noq 60S RIBOSOMAL
PROTEIN L11-B
(Saccharomyces
cerevisiae) 		3 / 3 ASN H  94
PHE H 126
TYR H 127
 None
 0.87A 4u15A-2noqH:
undetectable		 4u15A-2noqH:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2noq 60S RIBOSOMAL
PROTEIN L11-B
(Saccharomyces
cerevisiae) 		4 / 4 GLY H  82
LEU H  83
VAL H  85
GLU H  87
 None
 1.40A 5yw0A-2noqH:
undetectable		 5yw0A-2noqH:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2noq 60S RIBOSOMAL
PROTEIN L11-B
(Saccharomyces
cerevisiae) 		4 / 7 GLY H 102
PHE H 101
VAL H 129
SER H 118
 None
 1.06A 6hu9S-2noqH:
undetectable
6hu9q-2noqH:
undetectable		 6hu9S-2noqH:
17.37
6hu9q-2noqH:
20.96