SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2noz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.08A 3jwtA-2nozA:
undetectable
3jwtB-2nozA:
undetectable		 3jwtA-2nozA:
22.54
3jwtB-2nozA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.11A 3jwtA-2nozA:
undetectable
3jwtB-2nozA:
undetectable		 3jwtA-2nozA:
22.54
3jwtB-2nozA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.09A 3jx1A-2nozA:
undetectable
3jx1B-2nozA:
undetectable		 3jx1A-2nozA:
22.30
3jx1B-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 8 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.09A 3jx1A-2nozA:
undetectable
3jx1B-2nozA:
undetectable		 3jx1A-2nozA:
22.30
3jx1B-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.09A 3jx6A-2nozA:
undetectable
3jx6B-2nozA:
undetectable		 3jx6A-2nozA:
22.25
3jx6B-2nozA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.07A 3jx6A-2nozA:
undetectable
3jx6B-2nozA:
undetectable		 3jx6A-2nozA:
22.25
3jx6B-2nozA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.11A 3nljA-2nozA:
undetectable
3nljB-2nozA:
undetectable		 3nljA-2nozA:
22.25
3nljB-2nozA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 6 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.06A 3nlyA-2nozA:
undetectable
3nlyB-2nozA:
undetectable		 3nlyA-2nozA:
22.30
3nlyB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 8 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.10A 3nlyA-2nozA:
undetectable
3nlyB-2nozA:
undetectable		 3nlyA-2nozA:
22.30
3nlyB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.11A 3nnyA-2nozA:
undetectable
3nnyB-2nozA:
undetectable		 3nnyA-2nozA:
22.30
3nnyB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		3 / 3 GLN A  68
THR A  69
LEU A  93
 None
 0.67A 3ondA-2nozA:
undetectable		 3ondA-2nozA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		3 / 3 GLN A  68
THR A  69
LEU A  93
 None
 0.66A 3ondB-2nozA:
undetectable		 3ondB-2nozA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.09A 3pneA-2nozA:
undetectable
3pneB-2nozA:
1.1		 3pneA-2nozA:
22.30
3pneB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.08A 3pngA-2nozA:
undetectable
3pngB-2nozA:
undetectable		 3pngA-2nozA:
22.30
3pngB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.10A 3pngA-2nozA:
undetectable
3pngB-2nozA:
undetectable		 3pngA-2nozA:
22.30
3pngB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 6 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.11A 3rqkA-2nozA:
undetectable
3rqkB-2nozA:
undetectable		 3rqkA-2nozA:
22.30
3rqkB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.13A 3rqkA-2nozA:
undetectable
3rqkB-2nozA:
undetectable		 3rqkA-2nozA:
22.30
3rqkB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.15A 3svpA-2nozA:
undetectable
3svpB-2nozA:
undetectable		 3svpA-2nozA:
22.30
3svpB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 6 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.14A 3svpA-2nozA:
undetectable
3svpB-2nozA:
undetectable		 3svpA-2nozA:
22.30
3svpB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 6 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.14A 3svqA-2nozA:
undetectable
3svqB-2nozA:
undetectable		 3svqA-2nozA:
22.30
3svqB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.10A 3uftA-2nozA:
undetectable
3uftB-2nozA:
undetectable		 3uftA-2nozA:
22.30
3uftB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.10A 3uftA-2nozA:
undetectable
3uftB-2nozA:
undetectable		 3uftA-2nozA:
22.30
3uftB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 6 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.14A 4imuA-2nozA:
1.1
4imuB-2nozA:
0.0		 4imuA-2nozA:
22.30
4imuB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.16A 4imwA-2nozA:
undetectable
4imwB-2nozA:
undetectable		 4imwA-2nozA:
22.30
4imwB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 6 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 0.99A 4v3wA-2nozA:
undetectable
4v3wB-2nozA:
undetectable		 4v3wA-2nozA:
22.30
4v3wB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 PHE A 303
GLU A 298
VAL A 267
TRP A 272
 None
 1.13A 4v3wA-2nozA:
undetectable
4v3wB-2nozA:
undetectable		 4v3wA-2nozA:
22.30
4v3wB-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 7 VAL A 267
TRP A 272
PHE A 303
GLU A 298
 None
 1.08A 5ad4A-2nozA:
undetectable
5ad4B-2nozA:
undetectable		 5ad4A-2nozA:
22.30
5ad4B-2nozA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSE_C_HQEC1583_1
(UREASE SUBUNIT ALPHA)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 5 ILE A 254
GLN A 135
CYH A 140
GLU A 139
 None
 0.96A 5fseC-2nozA:
0.0		 5fseC-2nozA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 2noz N-GLYCOSYLASE/DNA
LYASE
(Homo
sapiens) 		4 / 6 LEU A  35
CYH A  75
HIS A  74
LEU A  66
 None
 1.20A 5hpuC-2nozA:
undetectable
5hpuD-2nozA:
undetectable		 5hpuC-2nozA:
6.23
5hpuD-2nozA:
5.82