SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		4 / 8 GLY A 276
ARG A 272
LEU A 282
VAL A 289
 None
 1.02A 1gsfC-2nq2A:
undetectable		 1gsfC-2nq2A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 12 ASP C  85
LEU A  78
HIS A 279
THR A 286
GLY A 276
 None
 1.20A 1ia0B-2nq2C:
undetectable		 1ia0B-2nq2C:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 9 PHE A 129
SER A 103
GLY A 102
LEU A 132
GLY A 130
 None
 1.25A 1jb0A-2nq2A:
1.9		 1jb0A-2nq2A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 12 VAL A 300
ALA A  21
ASN A 299
ALA A  69
ALA A 291
 None
 1.20A 1sa1C-2nq2A:
undetectable
1sa1D-2nq2A:
undetectable		 1sa1C-2nq2A:
20.53
1sa1D-2nq2A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 12 ASP C  85
LEU A  78
HIS A 279
THR A 286
GLY A 276
 None
 1.20A 1tubB-2nq2C:
undetectable		 1tubB-2nq2C:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
(Haemophilus
influenzae) 		3 / 3 LEU C 171
PHE C 184
ARG C 213
 None
 0.87A 1xdkB-2nq2C:
undetectable		 1xdkB-2nq2C:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
(Haemophilus
influenzae) 		5 / 10 ALA C 109
GLN C 133
LEU C 129
LEU C 113
ARG C 124
 None
 1.31A 2ceoB-2nq2C:
undetectable		 2ceoB-2nq2C:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 11 LEU A 249
SER A 246
LEU A  83
VAL A  82
VAL A 263
 None
 1.26A 2po5B-2nq2A:
undetectable		 2po5B-2nq2A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
(Haemophilus
influenzae) 		5 / 12 LEU C 170
VAL C 182
MET C 180
LEU C 152
THR C 156
 None
 1.26A 2q7kA-2nq2C:
undetectable		 2q7kA-2nq2C:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 12 LEU A 249
SER A 246
LEU A  83
VAL A  82
VAL A 263
 None
 1.33A 2qd4A-2nq2A:
undetectable		 2qd4A-2nq2A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_A_TDZA201_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		4 / 4 TYR A 293
MET A 294
PRO A  94
ILE A 266
 None
 1.25A 2qm9A-2nq2A:
undetectable		 2qm9A-2nq2A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		4 / 8 ILE A 267
LEU A 270
THR A 315
GLY A 290
 None
 0.86A 3dcjB-2nq2A:
undetectable		 3dcjB-2nq2A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 12 ALA A 190
GLY A 187
ILE A 260
ASP A 298
ALA A  69
 None
 1.09A 3n3iA-2nq2A:
undetectable		 3n3iA-2nq2A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 9 PHE A 129
SER A 103
GLY A 102
LEU A 132
GLY A 130
 None
 1.25A 3pcqA-2nq2A:
1.9		 3pcqA-2nq2A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		4 / 7 GLY A 247
SER A 246
PHE A  87
LEU A  83
 None
 0.74A 3v7pA-2nq2A:
undetectable		 3v7pA-2nq2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		4 / 7 GLY A 107
THR A 108
ILE A 111
THR A 191
 None
 0.95A 4acaC-2nq2A:
undetectable		 4acaC-2nq2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 11 ILE A 243
LEU A  78
LEU A 221
GLY A  85
PHE A  87
 None
 1.23A 4fogD-2nq2A:
undetectable		 4fogD-2nq2A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
(Haemophilus
influenzae) 		4 / 7 ILE C  62
LEU C  10
PHE C  12
GLY C  43
 None
 0.97A 4hajA-2nq2C:
undetectable		 4hajA-2nq2C:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 12 PHE A 204
GLY A  80
LEU A 265
HIS A  95
ILE A  96
 None
 1.01A 4krhB-2nq2A:
undetectable		 4krhB-2nq2A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
(Haemophilus
influenzae) 		5 / 9 ALA C 196
LEU C 171
PHE C 184
THR C 186
LEU C  37
 None
 1.30A 4ltwA-2nq2C:
undetectable		 4ltwA-2nq2C:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
(Haemophilus
influenzae) 		5 / 9 THR C 199
ALA C 196
LEU C 171
PHE C 184
THR C 186
 None
 1.35A 4ltwA-2nq2C:
undetectable		 4ltwA-2nq2C:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
(Haemophilus
influenzae) 		5 / 9 THR C 212
ALA C 196
LEU C 171
PHE C 184
LEU C  37
 None
 1.40A 4ltwA-2nq2C:
undetectable		 4ltwA-2nq2C:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 9 SER A 208
GLY A  75
ALA A  77
THR A 286
VAL A  82
 None
 1.26A 4r1zA-2nq2A:
undetectable		 4r1zA-2nq2A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 9 ILE A 260
GLY A  73
ALA A 291
ILE A  66
VAL A 297
 None
 1.09A 4r21B-2nq2A:
undetectable		 4r21B-2nq2A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
(Haemophilus
influenzae) 		4 / 7 LEU C 149
LEU C 151
GLU C  63
LEU C   5
 None
 0.78A 4wg0L-2nq2C:
undetectable
4wg0M-2nq2C:
undetectable		 4wg0L-2nq2C:
5.59
4wg0M-2nq2C:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470
(Haemophilus
influenzae) 		5 / 9 ALA C 109
GLN C 133
LEU C 129
LEU C 113
ARG C 124
 None
 1.24A 4x30A-2nq2C:
undetectable		 4x30A-2nq2C:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 12 PHE A 189
GLY A 187
LEU A  76
PHE A 204
THR A 292
 None
 1.07A 4zdyA-2nq2A:
1.4		 4zdyA-2nq2A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 12 GLY A 128
GLY A 102
GLY A 106
LEU A 126
LEU A 132
 None
 1.06A 5c0oH-2nq2A:
undetectable		 5c0oH-2nq2A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		3 / 3 ARG A 302
ILE A 311
PHE A 189
 None
 0.66A 5kirA-2nq2A:
undetectable		 5kirA-2nq2A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 9 PHE A 129
SER A 103
GLY A 102
LEU A 132
GLY A 130
 None
 1.26A 5l8rA-2nq2A:
undetectable		 5l8rA-2nq2A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		4 / 8 ILE A 243
LEU A 221
GLY A  85
PHE A  87
 None
 0.89A 5nooD-2nq2A:
undetectable		 5nooD-2nq2A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		4 / 7 LEU A 295
ASP A 298
ALA A 301
LEU A 304
 None
 1.06A 5nwvA-2nq2A:
undetectable		 5nwvA-2nq2A:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		4 / 5 LEU A 157
THR A 131
THR A 100
GLY A 102
 None
 1.27A 6gtqA-2nq2A:
undetectable		 6gtqA-2nq2A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471
(Haemophilus
influenzae) 		5 / 12 GLY A 261
GLY A 258
VAL A  72
ALA A 104
PHE A 189
 None
 1.01A 6nj9K-2nq2A:
undetectable		 6nj9K-2nq2A:
21.44