SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 ASP A 273
ARG A 277
ILE A 248
 None
 0.85A 1a4gB-2nqlA:
undetectable		 1a4gB-2nqlA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 ALA A 125
LEU A 123
THR A  69
VAL A  53
 None
 0.83A 1dvxB-2nqlA:
undetectable		 1dvxB-2nqlA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 11 VAL A 264
VAL A 254
SER A 255
LEU A 251
ALA A 239
 None
 1.10A 1eqgB-2nqlA:
undetectable		 1eqgB-2nqlA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 10 LEU A  81
VAL A 120
TYR A 119
TYR A 114
GLY A 117
 None
 1.44A 1fkoA-2nqlA:
undetectable		 1fkoA-2nqlA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 LEU A 160
PRO A 161
LEU A 171
 None
 0.53A 1hrkA-2nqlA:
undetectable		 1hrkA-2nqlA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 10 LEU A 126
ALA A 122
LEU A 105
ALA A  87
LEU A  85
 None
 1.32A 1ie4A-2nqlA:
undetectable
1ie4C-2nqlA:
undetectable		 1ie4A-2nqlA:
16.21
1ie4C-2nqlA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JQD_A_HSMA600_1
(HISTAMINE
N-METHYLTRANSFERASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 PHE A  11
GLU A   9
VAL A  64
TRP A  66
 None
 1.29A 1jqdA-2nqlA:
0.4		 1jqdA-2nqlA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 THR A 333
SER A 332
PHE A 153
LEU A 373
VAL A 375
 None
 1.34A 1q23D-2nqlA:
undetectable
1q23E-2nqlA:
undetectable		 1q23D-2nqlA:
18.62
1q23E-2nqlA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 LEU A 328
VAL A 375
GLY A 374
LEU A 324
 None
 1.03A 1s1xA-2nqlA:
undetectable		 1s1xA-2nqlA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 GLY A 294
ALA A 124
VAL A  78
GLY A  67
ILE A 322
 None
 1.00A 1sdtB-2nqlA:
undetectable		 1sdtB-2nqlA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 ASP A 359
PHE A 347
ARG A 351
 None
 0.66A 2a3aA-2nqlA:
4.0		 2a3aA-2nqlA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 6 GLU A 362
ASP A 359
PHE A 347
ARG A 351
 None
 1.16A 2a3bB-2nqlA:
4.3		 2a3bB-2nqlA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 ALA A 306
GLY A 309
VAL A 312
ASP A 311
GLY A 302
 GOL  A1103 ( 4.0A)
None
None
None
GOL  A1103 (-4.4A)
 1.06A 2f8lA-2nqlA:
undetectable		 2f8lA-2nqlA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 ILE A  82
PRO A 377
GLY A  65
TRP A  66
 None
 1.10A 2pnjB-2nqlA:
undetectable		 2pnjB-2nqlA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 ARG A  17
THR A 317
VAL A 318
 None
GOL  A1107 (-4.1A)
None
 0.92A 2q64A-2nqlA:
undetectable		 2q64A-2nqlA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 ARG A  17
THR A 317
VAL A 318
 None
GOL  A1107 (-4.1A)
None
 0.99A 2qakA-2nqlA:
undetectable		 2qakA-2nqlA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 LEU A  25
TRP A 217
THR A  44
HIS A 292
 None
 1.14A 2y69C-2nqlA:
undetectable
2y69N-2nqlA:
undetectable
2y69P-2nqlA:
undetectable		 2y69C-2nqlA:
18.35
2y69N-2nqlA:
22.60
2y69P-2nqlA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 9 VAL A 375
GLY A 374
GLY A 372
ILE A 295
ALA A 325
 None
 0.82A 2z0yB-2nqlA:
undetectable		 2z0yB-2nqlA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 PRO A 161
LEU A 171
ARG A 178
 None
 0.68A 3aqiA-2nqlA:
undetectable		 3aqiA-2nqlA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 VAL A  19
SER A 345
HIS A 344
LEU A 171
 None
 1.12A 3arrA-2nqlA:
1.3		 3arrA-2nqlA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 LEU A 328
SER A 331
PHE A 153
ALA A 155
 None
 0.67A 3ax9B-2nqlA:
undetectable		 3ax9B-2nqlA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 LEU A 354
ILE A 322
ARG A 376
GLY A  65
 None
 0.83A 3b9lA-2nqlA:
undetectable		 3b9lA-2nqlA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 ALA A 125
LEU A 123
THR A  69
VAL A  53
 None
 0.95A 3d2tA-2nqlA:
undetectable		 3d2tA-2nqlA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 6 ALA A 125
LEU A 123
THR A  69
VAL A  53
 None
 0.87A 3d2tB-2nqlA:
undetectable		 3d2tB-2nqlA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 THR A   7
GLU A   9
THR A  58
VAL A  64
 None
 0.61A 3em0B-2nqlA:
undetectable		 3em0B-2nqlA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 ILE A 128
VAL A 101
ILE A  91
VAL A   8
VAL A  55
 None
 1.25A 3iw1A-2nqlA:
undetectable		 3iw1A-2nqlA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 GLY A 179
PHE A 180
PHE A 347
PHE A 342
 None
 1.16A 3ko0D-2nqlA:
undetectable
3ko0E-2nqlA:
undetectable		 3ko0D-2nqlA:
13.65
3ko0E-2nqlA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 PHE A 347
PHE A 342
GLY A 179
PHE A 180
 None
 0.90A 3ko0O-2nqlA:
undetectable
3ko0Q-2nqlA:
undetectable		 3ko0O-2nqlA:
13.65
3ko0Q-2nqlA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 5 GLU A 162
LEU A 160
HIS A 344
GLY A 159
 None
 0.85A 3pp1A-2nqlA:
undetectable		 3pp1A-2nqlA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 HIS A 366
ARG A 361
GLU A 362
 None
 1.17A 3qf1A-2nqlA:
undetectable		 3qf1A-2nqlA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 SER A 327
ASP A 127
ASP A 103
 None
 0.87A 3uj7A-2nqlA:
undetectable		 3uj7A-2nqlA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 LEU A  25
TRP A 217
THR A  44
HIS A 292
 None
 1.22A 3wg7C-2nqlA:
undetectable
3wg7N-2nqlA:
undetectable
3wg7P-2nqlA:
undetectable		 3wg7C-2nqlA:
18.35
3wg7N-2nqlA:
22.60
3wg7P-2nqlA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 PRO A 288
SER A 331
HIS A 340
SER A 327
 None
 1.05A 4k7gB-2nqlA:
undetectable		 4k7gB-2nqlA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB304_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 4 GLY A  71
SER A  52
ARG A  51
PRO A  75
 None
 1.16A 4m93B-2nqlA:
undetectable
4m93C-2nqlA:
0.0		 4m93B-2nqlA:
20.26
4m93C-2nqlA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 5 LEU A 304
ASP A 273
ARG A 277
ILE A 248
 None
 1.05A 4mwrA-2nqlA:
undetectable		 4mwrA-2nqlA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 10 ALA A 381
ASP A 355
LEU A 354
LEU A  13
ALA A 320
 None
 1.19A 4zbrA-2nqlA:
undetectable		 4zbrA-2nqlA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 TRP A 217
THR A  44
HIS A 292
LEU A  25
 None
 1.21A 5b3sA-2nqlA:
undetectable
5b3sC-2nqlA:
undetectable
5b3sP-2nqlA:
undetectable		 5b3sA-2nqlA:
22.60
5b3sC-2nqlA:
18.35
5b3sP-2nqlA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 5 SER A 327
ALA A 326
HIS A 340
MET A 358
 None
 1.40A 5dzkc-2nqlA:
1.4
5dzkq-2nqlA:
undetectable		 5dzkc-2nqlA:
19.95
5dzkq-2nqlA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 5 SER A 327
ALA A 326
HIS A 340
MET A 358
 None
 1.39A 5dzkf-2nqlA:
undetectable
5dzkt-2nqlA:
undetectable		 5dzkf-2nqlA:
19.95
5dzkt-2nqlA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 7 GLY A 135
GLY A 372
SER A  99
LEU A 130
ALA A  95
 None
None
GOL  A1101 ( 4.6A)
None
None
 1.33A 5o96C-2nqlA:
undetectable		 5o96C-2nqlA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 9 LEU A 353
PRO A 377
GLY A 319
SER A 378
LEU A 384
 None
 1.47A 5o96E-2nqlA:
undetectable
5o96F-2nqlA:
undetectable		 5o96E-2nqlA:
22.68
5o96F-2nqlA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 10 VAL A 375
GLY A 374
GLY A 372
ILE A 295
ALA A 325
 None
 0.93A 5vm8B-2nqlA:
undetectable		 5vm8B-2nqlA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 TRP A 217
THR A  44
HIS A 292
LEU A  25
 None
 1.18A 5w97A-2nqlA:
undetectable
5w97C-2nqlA:
undetectable
5w97c-2nqlA:
undetectable		 5w97A-2nqlA:
22.60
5w97C-2nqlA:
18.35
5w97c-2nqlA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 TRP A 217
THR A  44
HIS A 292
LEU A  25
 None
 1.21A 5z85A-2nqlA:
undetectable
5z85C-2nqlA:
undetectable
5z85P-2nqlA:
undetectable		 5z85A-2nqlA:
22.60
5z85C-2nqlA:
18.35
5z85P-2nqlA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 TRP A 217
THR A  44
HIS A 292
LEU A  25
 None
 1.21A 5zcoA-2nqlA:
undetectable
5zcoC-2nqlA:
undetectable
5zcoP-2nqlA:
undetectable		 5zcoA-2nqlA:
22.60
5zcoC-2nqlA:
18.35
5zcoP-2nqlA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 LEU A  25
TRP A 217
THR A  44
HIS A 292
 None
 1.19A 5zcoC-2nqlA:
undetectable
5zcoN-2nqlA:
undetectable
5zcoP-2nqlA:
undetectable		 5zcoC-2nqlA:
18.35
5zcoN-2nqlA:
22.60
5zcoP-2nqlA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 TRP A 217
THR A  44
HIS A 292
LEU A  25
 None
 1.21A 5zcpA-2nqlA:
undetectable
5zcpC-2nqlA:
undetectable
5zcpP-2nqlA:
undetectable		 5zcpA-2nqlA:
22.60
5zcpC-2nqlA:
18.35
5zcpP-2nqlA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 LEU A  25
TRP A 217
THR A  44
HIS A 292
 None
 1.21A 5zcpC-2nqlA:
undetectable
5zcpN-2nqlA:
undetectable
5zcpP-2nqlA:
undetectable		 5zcpC-2nqlA:
18.35
5zcpN-2nqlA:
22.60
5zcpP-2nqlA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 2nql ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 ILE A 128
LEU A 373
GLY A 319
ALA A 320
LEU A 354
 None
 1.18A 5zwrA-2nqlA:
undetectable		 5zwrA-2nqlA:
23.13