SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		4 / 5 ARG A 175
ALA A  78
ALA A 183
GLU A 182
 None
 1.07A 1e7cA-2nqoA:
undetectable		 1e7cA-2nqoA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		4 / 5 GLY A  69
ILE A  68
VAL A  75
SER A  42
 None
 1.25A 1rs7A-2nqoA:
undetectable		 1rs7A-2nqoA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 11 GLY A 138
ALA A 141
PHE A 102
ALA A 145
LEU A 100
 None
 1.07A 1ukbA-2nqoA:
undetectable		 1ukbA-2nqoA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 9 ALA A 237
TYR A 232
ALA A 228
GLY A 230
ILE A 223
 None
 1.36A 2v7bA-2nqoA:
undetectable		 2v7bA-2nqoA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		4 / 6 HIS A  44
GLN A 213
ALA A  71
ALA A  73
 None
 1.07A 2xfhA-2nqoA:
undetectable		 2xfhA-2nqoA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 8 GLY A  51
ALA A  64
ASP A  63
GLY A  69
LEU A  72
 None
 1.36A 3em6A-2nqoA:
undetectable		 3em6A-2nqoA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 ASN A 298
GLU A 297
VAL A 267
ILE A 344
ASN A 345
 None
 1.27A 3jayA-2nqoA:
undetectable		 3jayA-2nqoA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 ASN A 298
GLY A 269
VAL A 267
ILE A 344
ASN A 345
 None
 1.27A 3jb2A-2nqoA:
undetectable		 3jb2A-2nqoA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 GLU A 297
GLY A 269
VAL A 267
ILE A 344
ASN A 345
 None
 1.22A 3jb2A-2nqoA:
undetectable		 3jb2A-2nqoA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		4 / 8 PHE A 197
ALA A 183
PHE A 187
ALA A  78
 None
 0.91A 3t3sD-2nqoA:
undetectable		 3t3sD-2nqoA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 GLY A  69
LEU A  72
ASN A  81
ALA A 145
LEU A 100
 None
 0.95A 3vywA-2nqoA:
undetectable		 3vywA-2nqoA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 GLY A  69
LEU A  72
ASN A  81
ALA A 145
LEU A 100
 None
 0.98A 3vywB-2nqoA:
undetectable		 3vywB-2nqoA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 GLY A  69
LEU A  72
ASN A  81
ALA A 145
LEU A 100
 None
 0.98A 3vywD-2nqoA:
undetectable		 3vywD-2nqoA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 9 ASN A  81
GLY A  84
GLY A  83
PHE A 231
GLY A  85
 None
 1.32A 3ztvA-2nqoA:
undetectable		 3ztvA-2nqoA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 11 LEU A 220
LEU A  72
PRO A  77
GLN A 213
ALA A 166
 None
 1.09A 4hwkB-2nqoA:
undetectable		 4hwkB-2nqoA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU A 220
LEU A  72
PRO A  77
GLN A 213
ALA A 166
 None
 1.12A 4hwkC-2nqoA:
undetectable		 4hwkC-2nqoA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 11 LEU A 220
LEU A  72
PRO A  77
GLN A 213
ALA A 166
 None
 1.12A 4hwkD-2nqoA:
undetectable		 4hwkD-2nqoA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		4 / 5 PHE A 211
THR A 179
PHE A 187
ILE A 172
 None
 1.19A 4jx1E-2nqoA:
undetectable		 4jx1E-2nqoA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 9 ALA A  67
ALA A  64
ALA A  40
SER A  42
ALA A  71
 None
 1.16A 4twdA-2nqoA:
undetectable
4twdB-2nqoA:
undetectable
4twdC-2nqoA:
undetectable
4twdD-2nqoA:
undetectable
4twdE-2nqoA:
undetectable		 4twdA-2nqoA:
21.52
4twdB-2nqoA:
21.52
4twdC-2nqoA:
21.52
4twdD-2nqoA:
21.52
4twdE-2nqoA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 10 ALA A  67
ILE A  68
GLY A  59
LEU A  55
ALA A  40
 None
 1.31A 5ajqB-2nqoA:
undetectable		 5ajqB-2nqoA:
22.61