SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nqw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A79_A_P1BA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	2nqw	CBS DOMAIN PROTEIN (Porphyromonas gingivalis)	5 / 12	PRO A 58 LEU A 51 LEU A 46 ILE A 81 PHE A 16	None	1.22A	4a79A-2nqwA: undetectable	4a79A-2nqwA: 11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A79_B_P1BB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	2nqw	CBS DOMAIN PROTEIN (Porphyromonas gingivalis)	5 / 12	PRO A 58 LEU A 51 LEU A 46 ILE A 81 PHE A 16	None	1.27A	4a79B-2nqwA: undetectable	4a79B-2nqwA: 11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZT_C_RTLC201_0 (RETINOL-BINDING PROTEIN 2)	2nqw	CBS DOMAIN PROTEIN (Porphyromonas gingivalis)	5 / 12	PHE A 36 ALA A 35 TYR A 14 LEU A 29 LEU A 46	None	1.31A	4qztC-2nqwA: undetectable	4qztC-2nqwA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YSI_A_NCAA1001_0 (UBIQUITINATING/DEUBI QUITINATING ENZYME SDEA)	2nqw	CBS DOMAIN PROTEIN (Porphyromonas gingivalis)	4 / 6	GLY A 40 SER A 23 THR A 45 VAL A 43	None	0.98A	5ysiA-2nqwA: undetectable	5ysiA-2nqwA: 24.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4A79_A_P1BA601_1","AMINE OXIDASE [FLAVIN-CONTAINING] B","2nqw","CBS DOMAIN PROTEIN","Porphyromonas gingivalis",5,"PRO A  58;LEU A  51;LEU A  46;ILE A  81;PHE A  16","None","1.22A","4a79A-2nqwA:undetectable","4a79A-2nqwA:11.96"],["4A79_B_P1BB601_1","AMINE OXIDASE [FLAVIN-CONTAINING] B","2nqw","CBS DOMAIN PROTEIN","Porphyromonas gingivalis",5,"PRO A  58;LEU A  51;LEU A  46;ILE A  81;PHE A  16","None","1.27A","4a79B-2nqwA:undetectable","4a79B-2nqwA:11.96"],["4QZT_C_RTLC201_0","RETINOL-BINDING PROTEIN 2","2nqw","CBS DOMAIN PROTEIN","Porphyromonas gingivalis",5,"PHE A  36;ALA A  35;TYR A  14;LEU A  29;LEU A  46","None","1.31A","4qztC-2nqwA:undetectable","4qztC-2nqwA:21.26"],["5YSI_A_NCAA1001_0","UBIQUITINATING\/DEUBIQUITINATING ENZYME SDEA","2nqw","CBS DOMAIN PROTEIN","Porphyromonas gingivalis",4,"GLY A  40;SER A  23;THR A  45;VAL A  43","None","0.98A","5ysiA-2nqwA:undetectable","5ysiA-2nqwA:24.83"]]