SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 ILE A 109
ALA A 141
LEU A 186
PHE A 139
ILE A 138
 None
 1.27A 1g5yB-2nr7A:
undetectable		 1g5yB-2nr7A:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 9 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.80A 1ohrB-2nr7A:
undetectable		 1ohrB-2nr7A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		4 / 4 ASP A  61
LEU A  56
LEU A  59
LEU A  12
 None
 1.34A 1u18A-2nr7A:
undetectable		 1u18A-2nr7A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 7 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.85A 2aojB-2nr7A:
undetectable		 2aojB-2nr7A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 9 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.81A 2avoA-2nr7A:
undetectable		 2avoA-2nr7A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 9 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.81A 2o4pB-2nr7A:
undetectable		 2o4pB-2nr7A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.83A 2q63A-2nr7A:
undetectable		 2q63A-2nr7A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.81A 2q64B-2nr7A:
undetectable		 2q64B-2nr7A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		4 / 8 GLY A 102
ILE A  11
THR A  37
TYR A  10
 None
 0.93A 2yoeB-2nr7A:
undetectable
2yoeC-2nr7A:
undetectable		 2yoeB-2nr7A:
21.38
2yoeC-2nr7A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		3 / 3 LEU A  69
TRP A  94
TYR A  10
 None
 0.97A 3aicF-2nr7A:
undetectable		 3aicF-2nr7A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 9 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.75A 3d1yB-2nr7A:
undetectable		 3d1yB-2nr7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.83A 3k4vB-2nr7A:
undetectable		 3k4vB-2nr7A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.83A 3ndtA-2nr7A:
undetectable		 3ndtA-2nr7A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.84A 3tl9A-2nr7A:
undetectable		 3tl9A-2nr7A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.79A 3tl9B-2nr7A:
undetectable		 3tl9B-2nr7A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 11 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.80A 4qgiB-2nr7A:
undetectable		 4qgiB-2nr7A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 10 LEU A 134
ALA A 141
ILE A 103
VAL A  87
ILE A 138
 None
 1.03A 5kr1A-2nr7A:
undetectable		 5kr1A-2nr7A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		4 / 5 GLY A 119
THR A 122
ASN A 120
LYS A 121
 None
 0.95A 5x23A-2nr7A:
undetectable		 5x23A-2nr7A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		4 / 6 GLY A 119
THR A 122
ASN A 120
LYS A 121
 None
 0.96A 5x24A-2nr7A:
1.7		 5x24A-2nr7A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 2nr7 SECRETION ACTIVATOR
PROTEIN, PUTATIVE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 134
GLY A 102
ILE A 103
VAL A  87
ILE A 138
 None
 0.77A 6dilB-2nr7A:
undetectable		 6dilB-2nr7A:
20.83