SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nra'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 2nra PI PROTEIN
(Escherichia
coli) 		4 / 4 LEU C 174
SER C 171
TYR C 170
LEU C 202
 None
 0.83A 1xz1A-2nraC:
undetectable		 1xz1A-2nraC:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 2nra PI PROTEIN
(Escherichia
coli) 		4 / 4 LEU C 174
SER C 171
TYR C 170
LEU C 202
 None
 0.82A 1xz3A-2nraC:
undetectable		 1xz3A-2nraC:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 2nra PI PROTEIN
(Escherichia
coli) 		5 / 12 LEU C  40
LEU C  84
LEU C  25
ILE C 141
LEU C 135
 None
 0.87A 2ouzA-2nraC:
undetectable		 2ouzA-2nraC:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 2nra PI PROTEIN
(Escherichia
coli) 		3 / 3 SER C 183
TYR C 182
HIS C 181
 None
 0.71A 2r2vD-2nraC:
undetectable		 2r2vD-2nraC:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2nra PI PROTEIN
(Escherichia
coli) 		3 / 3 TYR C 144
GLU C 102
ASN C 104
 None
 1.02A 2y7hC-2nraC:
undetectable		 2y7hC-2nraC:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2nra PI PROTEIN
(Escherichia
coli) 		5 / 8 LEU C 259
PHE C 191
PHE C 261
LEU C 228
PHE C 223
 None
 1.40A 3asoC-2nraC:
undetectable
3asoJ-2nraC:
undetectable		 3asoC-2nraC:
20.27
3asoJ-2nraC:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 2nra PI PROTEIN
(Escherichia
coli) 		4 / 6 LEU C 174
SER C 171
TYR C 170
LEU C 202
 None
 0.84A 3f33A-2nraC:
undetectable		 3f33A-2nraC:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2nra PI PROTEIN
(Escherichia
coli) 		5 / 12 ALA C  26
LEU C 202
ILE C 193
SER C 194
LEU C 174
 None
 1.19A 3nrrA-2nraC:
undetectable		 3nrrA-2nraC:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2nra PI PROTEIN
(Escherichia
coli) 		5 / 12 ALA C  26
LEU C 202
ILE C 193
SER C 194
LEU C 174
 None
 1.22A 3nrrB-2nraC:
undetectable		 3nrrB-2nraC:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 2nra PI PROTEIN
(Escherichia
coli) 		4 / 6 LEU C 174
SER C 171
TYR C 170
LEU C 202
 None
 0.79A 3ravA-2nraC:
undetectable		 3ravA-2nraC:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 2nra PI PROTEIN
(Escherichia
coli) 		4 / 7 PHE C 246
PHE C 261
ALA C 231
LEU C 198
 None
 0.63A 4ejgA-2nraC:
undetectable		 4ejgA-2nraC:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 2nra PI PROTEIN
(Escherichia
coli) 		4 / 8 PHE C 246
PHE C 261
ALA C 231
LEU C 198
 None
 0.73A 4ejgB-2nraC:
undetectable		 4ejgB-2nraC:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 2nra PI PROTEIN
(Escherichia
coli) 		4 / 7 PHE C 246
PHE C 261
ALA C 231
LEU C 198
 None
 0.66A 4ejgC-2nraC:
undetectable		 4ejgC-2nraC:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2nra PI PROTEIN
(Escherichia
coli) 		5 / 12 GLY C  81
TYR C  74
ILE C 121
ALA C  86
ALA C  32
 None
 1.10A 5kvaB-2nraC:
undetectable		 5kvaB-2nraC:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2nra PI PROTEIN
(Escherichia
coli) 		5 / 8 ILE C 121
LEU C  84
ILE C 120
ILE C 141
SER C  45
 None
 1.12A 5numA-2nraC:
undetectable		 5numA-2nraC:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2nra PI PROTEIN
(Escherichia
coli) 		4 / 5 LEU C 259
PHE C 191
LEU C 228
PHE C 223
 None
 1.27A 5xdxC-2nraC:
undetectable
5xdxJ-2nraC:
undetectable		 5xdxC-2nraC:
20.79
5xdxJ-2nraC:
11.95