SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nrq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 2nrq HYPOTHETICAL PROTEIN
ORF-C20_032
(Sulfolobus
solfataricus) 		5 / 12 ILE A  69
LEU A  97
PHE A  99
LEU A 112
ARG A 143
 None
 1.45A 2mjiA-2nrqA:
undetectable		 2mjiA-2nrqA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 2nrq HYPOTHETICAL PROTEIN
ORF-C20_032
(Sulfolobus
solfataricus) 		4 / 6 PHE A  67
LEU A  79
THR A  85
LEU A  97
 None
 0.95A 3t3zD-2nrqA:
undetectable		 3t3zD-2nrqA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 2nrq HYPOTHETICAL PROTEIN
ORF-C20_032
(Sulfolobus
solfataricus) 		3 / 3 LYS A 101
ILE A 119
ILE A   8
 None
 0.69A 4y0qA-2nrqA:
undetectable		 4y0qA-2nrqA:
22.62