SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nsg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		4 / 5 THR A 137
THR A  73
HIS A  65
HIS A 122
 None
 1.36A 1d4fA-2nsgA:
undetectable		 1d4fA-2nsgA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		4 / 5 THR A 137
THR A  73
HIS A  65
HIS A 122
 None
 1.36A 1d4fD-2nsgA:
undetectable		 1d4fD-2nsgA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		4 / 6 LEU A  63
LEU A 125
GLU A 136
MET A 140
 None
None
None
SO4  A 401 (-4.6A)
 1.08A 2kuhA-2nsgA:
undetectable		 2kuhA-2nsgA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		5 / 9 VAL A 207
VAL A 187
PRO A 235
GLY A 232
ARG A 196
 None
 1.26A 3bjwG-2nsgA:
1.5		 3bjwG-2nsgA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		4 / 5 THR A 137
THR A  73
HIS A  65
HIS A 122
 None
 1.40A 3g1uC-2nsgA:
undetectable		 3g1uC-2nsgA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		5 / 12 GLY A 214
ARG A 217
ILE A 161
ALA A 220
ASP A 151
 None
SO4  A 402 (-3.7A)
None
None
None
 1.03A 3gwwA-2nsgA:
undetectable		 3gwwA-2nsgA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		5 / 12 VAL A  53
VAL A 150
GLY A 153
SER A  39
LEU A  49
 None
 1.32A 3pghA-2nsgA:
0.0		 3pghA-2nsgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		4 / 5 THR A   2
LEU A   7
THR A 137
MET A 140
 None
None
None
SO4  A 401 (-4.6A)
 1.31A 4mbsB-2nsgA:
undetectable		 4mbsB-2nsgA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		3 / 3 ALA A  59
ASN A  62
LEU A  63
 None
 0.35A 5i1nB-2nsgA:
undetectable		 5i1nB-2nsgA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		3 / 3 ALA A  59
ASN A  62
LEU A  63
 None
 0.39A 5i1oA-2nsgA:
undetectable		 5i1oA-2nsgA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 2nsg HYPOTHETICAL PROTEIN
CGL3021
(Corynebacterium
glutamicum) 		4 / 8 ASN A  93
PRO A  94
PHE A  35
TYR A  55
 None
 1.45A 5oh1C-2nsgA:
undetectable		 5oh1C-2nsgA:
17.60