SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nsz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BRP_A_RTLA183_0 (RETINOL BINDING PROTEIN)	2nsz	PROGRAMMED CELL DEATH PROTEIN 4 (Mus musculus)	5 / 12	LEU A 387 ALA A 367 TYR A 338 LEU A 351 PHE A 429	None	1.18A	1brpA-2nszA: undetectable	1brpA-2nszA: 23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_E_FK5E201_1 (FK506-BINDING PROTEIN 1)	2nsz	PROGRAMMED CELL DEATH PROTEIN 4 (Mus musculus)	5 / 11	PHE A 380 ILE A 368 TYR A 405 ILE A 439 ILE A 438	None	1.17A	5hw8E-2nszA: undetectable	5hw8E-2nszA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_B_PCFB1806_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	2nsz	PROGRAMMED CELL DEATH PROTEIN 4 (Mus musculus)	4 / 6	ILE A 398 ILE A 368 HIS A 360 PHE A 380	None	0.99A	5vkqB-2nszA: 1.1 5vkqC-2nszA: 2.4	5vkqB-2nszA: 5.47 5vkqC-2nszA: 5.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1807_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	2nsz	PROGRAMMED CELL DEATH PROTEIN 4 (Mus musculus)	4 / 6	ILE A 398 ILE A 368 HIS A 360 PHE A 380	None	1.00A	5vkqC-2nszA: 2.4 5vkqD-2nszA: 2.4	5vkqC-2nszA: 5.47 5vkqD-2nszA: 5.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BRP_A_RTLA183_0","RETINOL BINDING PROTEIN","2nsz","PROGRAMMED CELL DEATH PROTEIN 4","Mus musculus",5,"LEU A 387;ALA A 367;TYR A 338;LEU A 351;PHE A 429","None","1.18A","1brpA-2nszA:undetectable","1brpA-2nszA:23.76"],["5HW8_E_FK5E201_1","FK506-BINDING PROTEIN 1","2nsz","PROGRAMMED CELL DEATH PROTEIN 4","Mus musculus",5,"PHE A 380;ILE A 368;TYR A 405;ILE A 439;ILE A 438","None","1.17A","5hw8E-2nszA:undetectable","5hw8E-2nszA:21.05"],["5VKQ_B_PCFB1806_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","2nsz","PROGRAMMED CELL DEATH PROTEIN 4","Mus musculus",4,"ILE A 398;ILE A 368;HIS A 360;PHE A 380","None","0.99A","5vkqB-2nszA:1.1;5vkqC-2nszA:2.4","5vkqB-2nszA:5.47;5vkqC-2nszA:5.47"],["5VKQ_C_PCFC1807_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","2nsz","PROGRAMMED CELL DEATH PROTEIN 4","Mus musculus",4,"ILE A 398;ILE A 368;HIS A 360;PHE A 380","None","1.00A","5vkqC-2nszA:2.4;5vkqD-2nszA:2.4","5vkqC-2nszA:5.47;5vkqD-2nszA:5.47"]]