SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nt8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		5 / 10 VAL A  41
LEU A  66
LEU A 158
TYR A 161
ALA A 127
 None
 1.41A 1pbcA-2nt8A:
undetectable		 1pbcA-2nt8A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 8 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.83A 1v54C-2nt8A:
2.7
1v54J-2nt8A:
undetectable		 1v54C-2nt8A:
21.30
1v54J-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 8 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.85A 1v54P-2nt8A:
2.7
1v54W-2nt8A:
undetectable		 1v54P-2nt8A:
21.30
1v54W-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 8 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.82A 2dyrC-2nt8A:
2.7
2dyrJ-2nt8A:
undetectable		 2dyrC-2nt8A:
21.30
2dyrJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 8 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.85A 2dyrP-2nt8A:
2.7
2dyrW-2nt8A:
undetectable		 2dyrP-2nt8A:
21.30
2dyrW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.86A 2eikC-2nt8A:
2.7
2eikJ-2nt8A:
undetectable		 2eikC-2nt8A:
21.30
2eikJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 8 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.89A 2eikP-2nt8A:
2.7
2eikW-2nt8A:
undetectable		 2eikP-2nt8A:
21.30
2eikW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 8 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.84A 2eilC-2nt8A:
2.8
2eilJ-2nt8A:
undetectable		 2eilC-2nt8A:
21.30
2eilJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 8 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.90A 2eilP-2nt8A:
2.7
2eilW-2nt8A:
undetectable		 2eilP-2nt8A:
21.30
2eilW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.90A 2eimP-2nt8A:
2.7
2eimW-2nt8A:
undetectable		 2eimP-2nt8A:
21.30
2eimW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 4 ALA A 166
VAL A 126
PHE A 162
THR A  44
 None
 1.27A 2pkkA-2nt8A:
undetectable		 2pkkA-2nt8A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		3 / 3 LEU A 172
TYR A 171
GLN A 174
 None
 0.69A 2wekA-2nt8A:
undetectable		 2wekA-2nt8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 6 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.88A 3abkP-2nt8A:
2.8
3abkW-2nt8A:
undetectable		 3abkP-2nt8A:
21.30
3abkW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 8 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.81A 3ag4C-2nt8A:
2.7
3ag4J-2nt8A:
undetectable		 3ag4C-2nt8A:
21.30
3ag4J-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.83A 3ag4P-2nt8A:
3.4
3ag4W-2nt8A:
undetectable		 3ag4P-2nt8A:
21.30
3ag4W-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.84A 3asnC-2nt8A:
2.7
3asnJ-2nt8A:
undetectable		 3asnC-2nt8A:
21.30
3asnJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.83A 3asnP-2nt8A:
2.7
3asnW-2nt8A:
undetectable		 3asnP-2nt8A:
21.30
3asnW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 8 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.85A 3asoC-2nt8A:
2.7
3asoJ-2nt8A:
undetectable		 3asoC-2nt8A:
21.30
3asoJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.85A 3asoP-2nt8A:
2.7
3asoW-2nt8A:
undetectable		 3asoP-2nt8A:
21.30
3asoW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		3 / 3 GLU A 135
LEU A 152
LEU A  65
 None
 0.76A 3ohtA-2nt8A:
undetectable		 3ohtA-2nt8A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		3 / 3 GLU A 135
LEU A 152
LEU A  65
 None
 0.78A 3ohtB-2nt8A:
undetectable		 3ohtB-2nt8A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 6 LEU A  59
VAL A  41
PHE A 162
PHE A 154
 None
 1.10A 3soaA-2nt8A:
2.1		 3soaA-2nt8A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 6 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.78A 3wg7C-2nt8A:
2.8
3wg7J-2nt8A:
undetectable		 3wg7C-2nt8A:
21.30
3wg7J-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 6 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 1.03A 3wg7P-2nt8A:
2.7
3wg7W-2nt8A:
undetectable		 3wg7P-2nt8A:
21.30
3wg7W-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.83A 3x2qC-2nt8A:
2.7
3x2qJ-2nt8A:
undetectable		 3x2qC-2nt8A:
21.30
3x2qJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.96A 3x2qP-2nt8A:
2.7
3x2qW-2nt8A:
undetectable		 3x2qP-2nt8A:
21.30
3x2qW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 5 ILE A 113
ARG A 132
ASP A 160
VAL A 106
 None
 1.08A 4nkxC-2nt8A:
undetectable		 4nkxC-2nt8A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 5 ILE A 113
ARG A 132
ASP A 160
VAL A 106
 None
 1.09A 4nkxD-2nt8A:
undetectable		 4nkxD-2nt8A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.82A 5b1aC-2nt8A:
2.7
5b1aJ-2nt8A:
undetectable		 5b1aC-2nt8A:
21.30
5b1aJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.84A 5b1aP-2nt8A:
2.8
5b1aW-2nt8A:
undetectable		 5b1aP-2nt8A:
21.30
5b1aW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.80A 5b1bP-2nt8A:
2.8
5b1bW-2nt8A:
undetectable		 5b1bP-2nt8A:
21.30
5b1bW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 1.01A 5b3sC-2nt8A:
2.7
5b3sJ-2nt8A:
undetectable		 5b3sC-2nt8A:
21.30
5b3sJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.83A 5iy5C-2nt8A:
2.7
5iy5J-2nt8A:
undetectable		 5iy5C-2nt8A:
22.34
5iy5J-2nt8A:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_B_K1SB304_0
(ADP-SUGAR
PYROPHOSPHATASE)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 5 TRP A  94
VAL A  93
LEU A  65
GLU A  97
 None
 1.48A 5qjqA-2nt8A:
0.0
5qjqB-2nt8A:
0.0		 5qjqA-2nt8A:
19.23
5qjqB-2nt8A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_C_K1SC305_0
(ADP-SUGAR
PYROPHOSPHATASE)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 5 GLU A  97
TRP A  94
VAL A  93
LEU A  65
 None
 1.43A 5qjqC-2nt8A:
0.0
5qjqD-2nt8A:
0.0		 5qjqC-2nt8A:
19.23
5qjqD-2nt8A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 5 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.88A 5x19C-2nt8A:
2.7
5x19J-2nt8A:
undetectable		 5x19C-2nt8A:
21.30
5x19J-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.81A 5x1fP-2nt8A:
2.7
5x1fW-2nt8A:
undetectable		 5x1fP-2nt8A:
21.30
5x1fW-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.83A 5z84C-2nt8A:
2.8
5z84J-2nt8A:
undetectable		 5z84C-2nt8A:
21.30
5z84J-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.84A 5z85C-2nt8A:
2.8
5z85J-2nt8A:
undetectable		 5z85C-2nt8A:
21.30
5z85J-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.80A 5zcoC-2nt8A:
2.7
5zcoJ-2nt8A:
undetectable		 5zcoC-2nt8A:
21.30
5zcoJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.82A 5zcqC-2nt8A:
2.8
5zcqJ-2nt8A:
undetectable		 5zcqC-2nt8A:
21.30
5zcqJ-2nt8A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2nt8 COBALAMIN
ADENOSYLTRANSFERASE
(Lactobacillus
reuteri) 		4 / 7 LEU A  95
PHE A 154
LEU A 158
PHE A 162
 None
 0.85A 5zcqP-2nt8A:
2.7
5zcqW-2nt8A:
undetectable		 5zcqP-2nt8A:
21.30
5zcqW-2nt8A:
12.11