SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nts'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	2nts	TRBC1 PROTEIN (Homo sapiens)	4 / 5	ARG P 68 MET P 77 THR P 20 LEU P 21	None	1.35A	2eimJ-2ntsP: undetectable	2eimJ-2ntsP: 11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	2nts	TRBC1 PROTEIN (Homo sapiens)	4 / 5	ARG P 68 MET P 77 THR P 20 LEU P 21	None	1.38A	2eimW-2ntsP: undetectable	2eimW-2ntsP: 11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	2nts	TRBC1 PROTEIN (Homo sapiens)	4 / 5	ARG P 68 MET P 77 THR P 20 LEU P 21	None	1.39A	3ag2J-2ntsP: undetectable	3ag2J-2ntsP: 11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	2nts	TRBC1 PROTEIN (Homo sapiens)	4 / 5	ARG P 68 MET P 77 THR P 20 LEU P 21	None	1.43A	3ag4J-2ntsP: undetectable	3ag4J-2ntsP: 11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_J_CHDJ101_1 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2nts	TRBC1 PROTEIN (Homo sapiens)	4 / 5	ARG P 68 MET P 77 THR P 20 LEU P 21	None	1.42A	5wauJ-2ntsP: undetectable	5wauJ-2ntsP: 11.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2EIM_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","2nts","TRBC1 PROTEIN","Homo sapiens",4,"ARG P  68;MET P  77;THR P  20;LEU P  21","None","1.35A","2eimJ-2ntsP:undetectable","2eimJ-2ntsP:11.30"],["2EIM_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","2nts","TRBC1 PROTEIN","Homo sapiens",4,"ARG P  68;MET P  77;THR P  20;LEU P  21","None","1.38A","2eimW-2ntsP:undetectable","2eimW-2ntsP:11.30"],["3AG2_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","2nts","TRBC1 PROTEIN","Homo sapiens",4,"ARG P  68;MET P  77;THR P  20;LEU P  21","None","1.39A","3ag2J-2ntsP:undetectable","3ag2J-2ntsP:11.30"],["3AG4_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","2nts","TRBC1 PROTEIN","Homo sapiens",4,"ARG P  68;MET P  77;THR P  20;LEU P  21","None","1.43A","3ag4J-2ntsP:undetectable","3ag4J-2ntsP:11.30"],["5WAU_J_CHDJ101_1","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2nts","TRBC1 PROTEIN","Homo sapiens",4,"ARG P  68;MET P  77;THR P  20;LEU P  21","None","1.42A","5wauJ-2ntsP:undetectable","5wauJ-2ntsP:11.30"]]