SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nuh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_C_H3PC554_1 (GLUTAMATE DEHYDROGENASE)	2nuh	PERIPLASMIC DIVALENT CATION TOLERANCE PROTEIN (Xylella fastidiosa)	4 / 5	ILE A 60 TYR A 6 ILE A 71 HIS A 78	None None IMD A 200 (-3.6A) None	1.24A	3eteB-2nuhA: undetectable 3eteC-2nuhA: undetectable	3eteB-2nuhA: 14.25 3eteC-2nuhA: 14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWX_A_EPAA1_2 (PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA)))	2nuh	PERIPLASMIC DIVALENT CATION TOLERANCE PROTEIN (Xylella fastidiosa)	5 / 12	CYH A 33 THR A 35 LEU A 7 ILE A 105 ILE A 101	None	1.26A	3gwxA-2nuhA: undetectable	3gwxA-2nuhA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCY_A_DB8A401_2 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	2nuh	PERIPLASMIC DIVALENT CATION TOLERANCE PROTEIN (Xylella fastidiosa)	4 / 4	VAL A 90 LEU A 94 ASN A 63 ASP A 4	None	1.38A	5vcyA-2nuhA: undetectable	5vcyA-2nuhA: 16.08

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ETE_C_H3PC554_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","2nuh","PERIPLASMIC DIVALENT CATION TOLERANCE PROTEIN","Xylella fastidiosa",4,"ILE A  60;TYR A   6;ILE A  71;HIS A  78","None;None;IMD A 200 (-3.6A);None","1.24A","3eteB-2nuhA:undetectable;3eteC-2nuhA:undetectable","3eteB-2nuhA:14.25;3eteC-2nuhA:14.25"],["3GWX_A_EPAA1_2","PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA))","2nuh","PERIPLASMIC DIVALENT CATION TOLERANCE PROTEIN","Xylella fastidiosa",5,"CYH A  33;THR A  35;LEU A   7;ILE A 105;ILE A 101","None","1.26A","3gwxA-2nuhA:undetectable","3gwxA-2nuhA:18.52"],["5VCY_A_DB8A401_2","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","2nuh","PERIPLASMIC DIVALENT CATION TOLERANCE PROTEIN","Xylella fastidiosa",4,"VAL A  90;LEU A  94;ASN A  63;ASP A   4","None","1.38A","5vcyA-2nuhA:undetectable","5vcyA-2nuhA:16.08"]]