SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		3 / 3 PHE A 123
TYR A  36
TYR A  30
 None
 0.94A 1x70B-2nulA:
undetectable		 1x70B-2nulA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		5 / 12 GLY A 129
ASN A   7
ASP A 154
ILE A 156
VAL A 126
 None
 1.07A 2hmyB-2nulA:
undetectable		 2hmyB-2nulA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		4 / 5 PHE A  27
PHE A  98
PHE A  41
VAL A   2
 None
 1.26A 2lh6A-2nulA:
undetectable		 2lh6A-2nulA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		4 / 7 LEU A  83
PHE A  27
ILE A 157
GLY A  81
 None
 0.91A 2v0mC-2nulA:
undetectable		 2v0mC-2nulA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		4 / 8 SER A  93
THR A  23
LEU A  76
THR A  64
 None
 1.10A 2v0zO-2nulA:
undetectable		 2v0zO-2nulA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		5 / 12 PHE A  99
GLY A  52
HIS A  42
ILE A 100
ASN A 101
 None
 1.35A 3a25A-2nulA:
undetectable		 3a25A-2nulA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		4 / 7 PHE A 123
MET A  85
ILE A 100
VAL A 126
 None
 1.03A 3p6hA-2nulA:
undetectable		 3p6hA-2nulA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		4 / 8 PHE A  98
PHE A  27
ALA A 124
PHE A  41
 None
 0.98A 3t3sF-2nulA:
undetectable		 3t3sF-2nulA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		5 / 12 LEU A  83
PHE A  27
ILE A 100
GLY A  52
THR A  39
 None
 1.13A 4nkvA-2nulA:
undetectable		 4nkvA-2nulA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		5 / 12 LEU A  83
PHE A  27
ILE A 100
GLY A  52
THR A  39
 None
 1.15A 4nkvC-2nulA:
undetectable		 4nkvC-2nulA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		5 / 12 LEU A  83
PHE A  27
ILE A 100
GLY A  52
THR A  39
 None
 1.13A 4nkvD-2nulA:
undetectable		 4nkvD-2nulA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		4 / 8 VAL A   2
ILE A  13
ILE A 136
PHE A  98
 None
 0.84A 5hw8H-2nulA:
undetectable		 5hw8H-2nulA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 2nul PEPTIDYLPROLYL
ISOMERASE
(Escherichia
coli) 		5 / 12 GLY A 129
ASN A   7
ASP A 154
ILE A 156
VAL A 126
 None
 0.99A 6mhtA-2nulA:
undetectable		 6mhtA-2nulA:
19.25