SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		3 / 3 TRP A 257
GLN A 236
TRP A  92
 None
 1.39A 2vqyA-2nunA:
undetectable		 2vqyA-2nunA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		5 / 12 VAL A 128
ALA A 181
LEU A 194
THR A 184
LEU A 187
 None
 1.13A 3p2kB-2nunA:
undetectable		 3p2kB-2nunA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		5 / 10 ALA A 136
ARG A 137
VAL A 138
TYR A 131
ILE A 298
 None
None
None
TRS  A1503 (-4.9A)
None
 1.50A 3retA-2nunA:
1.5
3retB-2nunA:
undetectable		 3retA-2nunA:
15.81
3retB-2nunA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		4 / 7 GLY A  77
GLY A 284
TYR A  70
ALA A 278
 None
 0.93A 5e26A-2nunA:
undetectable
5e26B-2nunA:
undetectable		 5e26A-2nunA:
21.03
5e26B-2nunA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		5 / 7 TYR A  70
GLU A 286
GLY A  31
SER A 281
GLY A  77
 None
 1.40A 5e26A-2nunA:
undetectable
5e26B-2nunA:
undetectable		 5e26A-2nunA:
21.03
5e26B-2nunA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		5 / 12 ILE A 238
TYR A 234
GLY A  31
LEU A 242
GLY A  84
 None
 0.98A 5i73A-2nunA:
undetectable		 5i73A-2nunA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		4 / 5 GLU A 286
GLY A  31
SER A 281
GLY A  77
 None
 1.10A 5kprA-2nunA:
undetectable		 5kprA-2nunA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		4 / 6 LEU A  91
SER A  81
ARG A  82
GLY A  77
 None
 1.13A 5o4yF-2nunA:
undetectable		 5o4yF-2nunA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		3 / 3 TYR A 222
LEU A 168
ASP A 232
 None
 0.89A 5zv2B-2nunA:
undetectable		 5zv2B-2nunA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 2nun AVIRULENCE B PROTEIN
(Pseudomonas
savastanoi) 		5 / 9 LEU A  91
ARG A  82
ALA A  76
SER A  72
ASP A  78
 None
 1.03A 6c2mB-2nunA:
undetectable		 6c2mB-2nunA:
11.75