SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 12 GLY A 166
ALA A 158
SER A 150
ALA A  86
GLN A 161
 None
 1.17A 1nt2A-2nv0A:
undetectable		 1nt2A-2nv0A:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 11 LEU A  44
GLY A  46
GLY A  47
LEU A  85
LEU A  82
 None
 1.01A 2qmmA-2nv0A:
2.6
2qmmB-2nv0A:
2.5		 2qmmA-2nv0A:
22.94
2qmmB-2nv0A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 11 ARG A  66
LEU A  97
ILE A  83
PRO A  95
ILE A  84
 None
 0.97A 3ebzA-2nv0A:
undetectable		 3ebzA-2nv0A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 10 LEU A  44
GLY A  41
GLY A  27
LEU A  28
ILE A  43
 None
 0.94A 3em3A-2nv0A:
undetectable		 3em3A-2nv0A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 12 GLY A   5
VAL A   6
LEU A 165
CYH A  23
ILE A  17
 None
 1.19A 3h52B-2nv0A:
undetectable		 3h52B-2nv0A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 11 ARG A  66
LEU A  97
ILE A  83
PRO A  95
ILE A  84
 None
 1.01A 3s53B-2nv0A:
undetectable		 3s53B-2nv0A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		4 / 5 LEU A 165
GLY A 166
ILE A 122
LYS A 123
 None
 1.20A 4ma8C-2nv0A:
undetectable		 4ma8C-2nv0A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 12 LEU A  85
LEU A  82
GLY A  81
MET A  52
ILE A  56
 None
 1.41A 4oktA-2nv0A:
undetectable		 4oktA-2nv0A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 7 GLU A  63
LEU A  65
ASN A  37
LEU A  36
LEU A  42
 None
 1.22A 4wg0B-2nv0A:
undetectable
4wg0C-2nv0A:
undetectable		 4wg0B-2nv0A:
5.65
4wg0C-2nv0A:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 12 PHE A 169
GLY A  81
ALA A 136
VAL A 179
PHE A  76
 None
 1.07A 4wnwB-2nv0A:
undetectable		 4wnwB-2nv0A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 12 VAL A  29
GLY A  11
ALA A  12
HIS A  16
ILE A  17
 None
 1.00A 4xdrA-2nv0A:
undetectable		 4xdrA-2nv0A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		4 / 4 ILE A  84
ILE A  56
ARG A  53
LEU A  85
 None
 1.33A 5dzkh-2nv0A:
undetectable
5dzkn-2nv0A:
undetectable
5dzkv-2nv0A:
undetectable		 5dzkh-2nv0A:
22.67
5dzkn-2nv0A:
22.67
5dzkv-2nv0A:
2.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2nv0 GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT
(Bacillus
subtilis) 		5 / 12 LEU A  44
GLY A  46
GLY A  47
LEU A  85
LEU A  82
 None
 1.01A 5twjA-2nv0A:
undetectable		 5twjA-2nv0A:
27.09