SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 2nv5 PTPRD, PHOSPHATASE
(Rattus
norvegicus) 		4 / 8 SER A1246
LEU A1270
ASP A1280
GLU A1316
 None
 1.14A 1mxgA-2nv5A:
undetectable		 1mxgA-2nv5A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2nv5 PTPRD, PHOSPHATASE
(Rattus
norvegicus) 		4 / 7 TYR A1257
VAL A1428
GLY A1429
THR A1469
 None
 0.93A 2a1mA-2nv5A:
undetectable		 2a1mA-2nv5A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2nv5 PTPRD, PHOSPHATASE
(Rattus
norvegicus) 		5 / 12 LEU A1270
ILE A1297
THR A1299
ASP A1309
LEU A1371
 None
 1.14A 2jn3A-2nv5A:
0.3		 2jn3A-2nv5A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 2nv5 PTPRD, PHOSPHATASE
(Rattus
norvegicus) 		3 / 3 ASN A1255
ASN A1283
ARG A1463
 None
 0.69A 2rlcA-2nv5A:
undetectable		 2rlcA-2nv5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 2nv5 PTPRD, PHOSPHATASE
(Rattus
norvegicus) 		3 / 3 ARG A1267
ASP A1309
ASN A1251
 None
 0.85A 2zzmA-2nv5A:
undetectable		 2zzmA-2nv5A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 2nv5 PTPRD, PHOSPHATASE
(Rattus
norvegicus) 		4 / 6 ALA A1262
ILE A1261
VAL A1428
ASN A1464
 None
 1.19A 3nneG-2nv5A:
undetectable		 3nneG-2nv5A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 2nv5 PTPRD, PHOSPHATASE
(Rattus
norvegicus) 		5 / 12 VAL A1422
ALA A1298
PHE A1405
PHE A1434
GLY A1432
 None
 1.25A 4mm6A-2nv5A:
undetectable		 4mm6A-2nv5A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2nv5 PTPRD, PHOSPHATASE
(Rattus
norvegicus) 		3 / 3 TYR A1473
ALA A1479
LEU A1480
 None
 0.53A 6ag0C-2nv5A:
undetectable		 6ag0C-2nv5A:
16.19