SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nvn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 2nvn HYPOTHETICAL PROTEIN
(Synechococcus
elongatus) 		3 / 3 ALA A 106
VAL A 108
TRP A 103
 None
 0.95A 1av2A-2nvnA:
undetectable
1av2B-2nvnA:
undetectable		 1av2A-2nvnA:
10.48
1av2B-2nvnA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 2nvn HYPOTHETICAL PROTEIN
(Synechococcus
elongatus) 		3 / 3 TRP A 103
ALA A 106
VAL A 108
 None
 0.96A 1av2C-2nvnA:
undetectable
1av2D-2nvnA:
undetectable		 1av2C-2nvnA:
10.48
1av2D-2nvnA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 2nvn HYPOTHETICAL PROTEIN
(Synechococcus
elongatus) 		3 / 3 ALA A 106
VAL A 108
TRP A 103
 None
 0.96A 1w5uA-2nvnA:
undetectable
1w5uB-2nvnA:
undetectable		 1w5uA-2nvnA:
10.48
1w5uB-2nvnA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 2nvn HYPOTHETICAL PROTEIN
(Synechococcus
elongatus) 		4 / 7 PRO A 104
LEU A  13
GLY A  10
ALA A 107
 GOL  A 122 ( 4.9A)
None
None
None
 1.00A 3tehB-2nvnA:
undetectable		 3tehB-2nvnA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2nvn HYPOTHETICAL PROTEIN
(Synechococcus
elongatus) 		4 / 7 GLY A  82
ALA A 105
ASP A  85
PHE A  83
 None
 1.00A 5mvsA-2nvnA:
undetectable		 5mvsA-2nvnA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 2nvn HYPOTHETICAL PROTEIN
(Synechococcus
elongatus) 		4 / 8 LEU A  93
LEU A  76
LEU A  25
GLY A  14
 None
 0.59A 6ce2A-2nvnA:
undetectable		 6ce2A-2nvnA:
17.91