SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nw0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 2nw0 PLYB
(unidentified
phage) 		4 / 7 TYR A 121
ALA A  59
TYR A  58
GLU A  92
 ACT  A1020 (-3.8A)
None
ACT  A1020 ( 3.9A)
ACT  A1020 (-3.8A)
 0.87A 1dmaA-2nw0A:
undetectable		 1dmaA-2nw0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 2nw0 PLYB
(unidentified
phage) 		4 / 6 ALA A  69
LEU A 110
GLU A  72
LEU A 120
 None
 0.95A 1mt1D-2nw0A:
undetectable
1mt1E-2nw0A:
undetectable		 1mt1D-2nw0A:
19.89
1mt1E-2nw0A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 2nw0 PLYB
(unidentified
phage) 		4 / 8 GLU A 160
GLN A 157
TYR A 121
TYR A  58
 None
ACT  A1020 (-3.1A)
ACT  A1020 (-3.8A)
ACT  A1020 ( 3.9A)
 1.42A 2aoxA-2nw0A:
undetectable		 2aoxA-2nw0A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 2nw0 PLYB
(unidentified
phage) 		5 / 11 ARG A 174
ILE A   4
ILE A  27
GLY A 177
PHE A 184
 None
 1.21A 2azyA-2nw0A:
undetectable		 2azyA-2nw0A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 2nw0 PLYB
(unidentified
phage) 		4 / 6 SER A 180
LEU A 181
ASP A 182
LEU A 175
 None
 0.64A 4wozA-2nw0A:
8.5
4wozB-2nw0A:
8.6		 4wozA-2nw0A:
18.24
4wozB-2nw0A:
18.24