SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nwh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.94A 1bx4A-2nwhA:
25.1		 1bx4A-2nwhA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 10 LEU A 150
ALA A 163
ILE A 166
GLY A  39
GLY A  40
 None
None
CL  A 403 ( 4.3A)
CL  A 403 (-4.2A)
None
 1.02A 1k6cA-2nwhA:
undetectable		 1k6cA-2nwhA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 209
ASP A 204
ILE A 236
GLU A 188
ARG A 221
 None
 1.48A 1l7fA-2nwhA:
undetectable		 1l7fA-2nwhA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.96A 1liiA-2nwhA:
25.0		 1liiA-2nwhA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.99A 1likA-2nwhA:
25.6		 1likA-2nwhA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 10 ARG A  74
ALA A  44
GLY A  38
GLY A  37
ILE A  56
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 1sdvA-2nwhA:
undetectable		 1sdvA-2nwhA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.95A 2c49A-2nwhA:
25.5		 2c49A-2nwhA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		4 / 7 ASP A  13
GLY A  37
GLY A  38
ASN A  42
 None
None
CL  A 403 (-3.5A)
None
 0.26A 2c49B-2nwhA:
27.8		 2c49B-2nwhA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		3 / 3 THR A  84
PRO A  59
PRO A  82
 None
 0.89A 2d55C-2nwhA:
undetectable		 2d55C-2nwhA:
2.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 161
ASP A 139
ALA A 261
PHE A  52
VAL A   6
 None
 1.46A 2g70A-2nwhA:
4.0		 2g70A-2nwhA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 161
ASP A 139
ALA A 261
PHE A  52
VAL A   6
 None
 1.42A 2g70B-2nwhA:
4.0		 2g70B-2nwhA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 161
ASP A 139
ALA A 261
PHE A  52
VAL A   6
 None
 1.41A 2g72A-2nwhA:
3.9		 2g72A-2nwhA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.97A 2pkkA-2nwhA:
23.8		 2pkkA-2nwhA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A  43
LEU A 260
PHE A 185
ILE A 181
LEU A 174
 None
 1.00A 2w3bA-2nwhA:
undetectable		 2w3bA-2nwhA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A  43
LEU A 260
PHE A 185
ILE A 181
LEU A 174
 None
 1.03A 2w3bB-2nwhA:
undetectable		 2w3bB-2nwhA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A  43
LEU A 260
PHE A 185
ILE A 181
LEU A 174
 None
 1.03A 2w3mA-2nwhA:
undetectable		 2w3mA-2nwhA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		4 / 7 ASN A  42
ALA A  73
ALA A  72
ALA A  76
 None
 0.78A 3a2qA-2nwhA:
undetectable		 3a2qA-2nwhA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		3 / 3 ARG A  88
ASP A  63
ASP A  87
 None
 0.90A 3jb3A-2nwhA:
undetectable		 3jb3A-2nwhA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		4 / 5 ILE A 282
THR A 283
THR A 290
SER A 291
 None
 1.21A 3snfA-2nwhA:
undetectable		 3snfA-2nwhA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.89A 3uboA-2nwhA:
25.3		 3uboA-2nwhA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.94A 3uboB-2nwhA:
26.5		 3uboB-2nwhA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.94A 4e3aA-2nwhA:
26.5		 4e3aA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 10 PHE A  52
LEU A  50
GLY A  51
ALA A 309
MET A 311
 None
 1.37A 4fe1A-2nwhA:
undetectable
4fe1J-2nwhA:
undetectable		 4fe1A-2nwhA:
18.52
4fe1J-2nwhA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4jksA-2nwhA:
26.6		 4jksA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.89A 4jksB-2nwhA:
26.6		 4jksB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4jkuA-2nwhA:
26.5		 4jkuA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.89A 4jkuB-2nwhA:
26.6		 4jkuB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4k8cA-2nwhA:
26.6		 4k8cA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4k8cB-2nwhA:
26.5		 4k8cB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4k8kA-2nwhA:
26.5		 4k8kA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4k8kB-2nwhA:
26.6		 4k8kB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.92A 4k8pA-2nwhA:
26.6		 4k8pA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4k8pB-2nwhA:
26.6		 4k8pB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.95A 4k8tA-2nwhA:
26.6		 4k8tA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.93A 4k8tB-2nwhA:
26.5		 4k8tB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4k93A-2nwhA:
26.6		 4k93A-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4k93B-2nwhA:
26.6		 4k93B-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4k9cA-2nwhA:
26.7		 4k9cA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.92A 4k9cB-2nwhA:
26.6		 4k9cB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4k9iA-2nwhA:
26.5		 4k9iA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4k9iB-2nwhA:
26.6		 4k9iB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.92A 4kadA-2nwhA:
26.6		 4kadA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4kadB-2nwhA:
26.4		 4kadB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4kahA-2nwhA:
26.6		 4kahA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.92A 4kahB-2nwhA:
26.7		 4kahB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4kalA-2nwhA:
26.7		 4kalA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4kalB-2nwhA:
26.6		 4kalB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4kanA-2nwhA:
26.5		 4kanA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4kanB-2nwhA:
26.6		 4kanB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.92A 4kbeA-2nwhA:
26.5		 4kbeA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.92A 4kbeB-2nwhA:
26.6		 4kbeB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A  43
LEU A 260
PHE A 185
ILE A 181
LEU A 174
 None
 1.04A 4kebB-2nwhA:
undetectable		 4kebB-2nwhA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFJ_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A  43
LEU A 260
PHE A 185
ILE A 181
LEU A 174
 None
 1.01A 4kfjB-2nwhA:
2.0		 4kfjB-2nwhA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4lbgA-2nwhA:
26.5		 4lbgA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4lbgB-2nwhA:
26.6		 4lbgB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.91A 4lbxA-2nwhA:
26.6		 4lbxA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.92A 4lbxB-2nwhA:
26.6		 4lbxB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.92A 4lc4A-2nwhA:
26.6		 4lc4A-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.92A 4lc4B-2nwhA:
26.5		 4lc4B-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4lcaA-2nwhA:
26.7		 4lcaA-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.90A 4lcaB-2nwhA:
26.6		 4lcaB-2nwhA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A  43
LEU A 260
PHE A 185
ILE A 181
LEU A 174
 None
 1.05A 4m6kA-2nwhA:
2.2		 4m6kA-2nwhA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 209
ASP A 204
ILE A 236
GLU A 188
ARG A 221
 None
 1.47A 4mwvA-2nwhA:
undetectable		 4mwvA-2nwhA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.97A 4n09B-2nwhA:
26.4		 4n09B-2nwhA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.97A 4n09D-2nwhA:
26.3		 4n09D-2nwhA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		4 / 6 ALA A  43
GLY A 258
ILE A 164
VAL A 218
 None
 0.72A 4r21A-2nwhA:
undetectable		 4r21A-2nwhA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ASP A  13
GLY A  37
GLY A  38
ASN A  42
ASP A 253
 None
None
CL  A 403 (-3.5A)
None
None
 0.96A 4ubeA-2nwhA:
23.8		 4ubeA-2nwhA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		4 / 6 PHE A 185
GLY A 258
TYR A 259
ALA A 272
 None
 1.04A 4yshB-2nwhA:
3.7		 4yshB-2nwhA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		4 / 6 PHE A 185
GLY A 276
TYR A 259
ALA A 272
 None
 1.25A 4yshB-2nwhA:
3.7		 4yshB-2nwhA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A  43
GLY A   8
GLY A  40
GLY A  38
LEU A   7
 None
None
None
CL  A 403 (-3.5A)
None
 0.96A 5c0oH-2nwhA:
5.2		 5c0oH-2nwhA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A  44
GLY A   8
GLY A  40
GLY A  38
LEU A   7
 None
None
None
CL  A 403 (-3.5A)
None
 1.05A 5c0oH-2nwhA:
5.2		 5c0oH-2nwhA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		4 / 4 CYH A 138
LEU A 161
LEU A 150
ALA A 154
 None
 1.09A 5hpuA-2nwhA:
undetectable
5hpuB-2nwhA:
undetectable		 5hpuA-2nwhA:
5.74
5hpuB-2nwhA:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 TYR A 113
ASP A  13
HIS A  11
GLU A  35
ARG A  60
 None
None
CL  A 403 ( 4.9A)
None
None
 0.98A 5igvA-2nwhA:
undetectable		 5igvA-2nwhA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 12 TYR A 113
ASP A  13
HIS A  11
GLU A  35
ARG A  60
 None
None
CL  A 403 ( 4.9A)
None
None
 0.93A 5igwA-2nwhA:
undetectable		 5igwA-2nwhA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		3 / 3 ASP A 139
ASN A  42
PHE A  83
 None
 0.80A 5jglB-2nwhA:
3.0		 5jglB-2nwhA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 11 ALA A 256
ALA A 162
GLY A  39
GLY A  40
ALA A  43
 None
None
CL  A 403 (-4.2A)
None
None
 1.04A 5lf3K-2nwhA:
2.3
5lf3L-2nwhA:
undetectable		 5lf3K-2nwhA:
23.45
5lf3L-2nwhA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		5 / 9 VAL A   6
LEU A 137
ILE A 164
ILE A 166
ALA A  58
 None
None
None
CL  A 403 ( 4.3A)
None
 0.95A 5nunA-2nwhA:
undetectable		 5nunA-2nwhA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 2nwh CARBOHYDRATE KINASE
(Agrobacterium
fabrum) 		4 / 5 PHE A 116
THR A  84
ASP A  80
ASN A  42
 None
 1.43A 5ybbA-2nwhA:
undetectable		 5ybbA-2nwhA:
21.36