SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nwi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 2nwi HYPOTHETICAL PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 ILE A  96
TYR A 139
ILE A 151
ALA A  72
GLU A 153
 None
 1.38A 1mrgA-2nwiA:
undetectable		 1mrgA-2nwiA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 2nwi HYPOTHETICAL PROTEIN
(Archaeoglobus
fulgidus) 		5 / 10 ALA A 107
LEU A  89
LEU A  81
LEU A 148
ARG A  58
 None
 1.36A 2ceoB-2nwiA:
undetectable		 2ceoB-2nwiA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 2nwi HYPOTHETICAL PROTEIN
(Archaeoglobus
fulgidus) 		4 / 4 ILE A   4
ARG A 109
ILE A   7
THR A  23
 None
 1.29A 3ia4C-2nwiA:
undetectable		 3ia4C-2nwiA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2nwi HYPOTHETICAL PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 PRO A  95
ILE A  94
SER A  14
THR A  16
 None
 0.99A 5vkqA-2nwiA:
undetectable
5vkqD-2nwiA:
undetectable		 5vkqA-2nwiA:
6.81
5vkqD-2nwiA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2nwi HYPOTHETICAL PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 SER A  14
THR A  16
PRO A  95
ILE A  94
 None
 1.06A 5vkqA-2nwiA:
undetectable
5vkqB-2nwiA:
undetectable		 5vkqA-2nwiA:
6.81
5vkqB-2nwiA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2nwi HYPOTHETICAL PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 SER A  14
THR A  16
PRO A  95
ILE A  94
 None
 1.04A 5vkqB-2nwiA:
undetectable
5vkqC-2nwiA:
undetectable		 5vkqB-2nwiA:
6.81
5vkqC-2nwiA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2nwi HYPOTHETICAL PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 SER A  14
THR A  16
PRO A  95
ILE A  94
 None
 1.04A 5vkqC-2nwiA:
undetectable
5vkqD-2nwiA:
undetectable		 5vkqC-2nwiA:
6.81
5vkqD-2nwiA:
6.81