SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nx2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 2nx2 HYPOTHETICAL PROTEIN
YPSA
(Bacillus
subtilis) 		4 / 8 VAL A  54
TYR A   9
GLY A  53
LEU A 135
 None
 0.97A 1jlbA-2nx2A:
undetectable		 1jlbA-2nx2A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 2nx2 HYPOTHETICAL PROTEIN
YPSA
(Bacillus
subtilis) 		4 / 5 LEU A 133
GLY A 132
ILE A 127
PHE A 126
 None
 0.96A 1xf1A-2nx2A:
undetectable		 1xf1A-2nx2A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 2nx2 HYPOTHETICAL PROTEIN
YPSA
(Bacillus
subtilis) 		3 / 3 PRO A  79
SER A  49
ASN A 123
 None
 0.94A 3lslG-2nx2A:
undetectable		 3lslG-2nx2A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2nx2 HYPOTHETICAL PROTEIN
YPSA
(Bacillus
subtilis) 		4 / 7 LYS A  32
LEU A  35
LEU A  65
LEU A  72
 None
 0.81A 4wg0B-2nx2A:
undetectable
4wg0C-2nx2A:
undetectable		 4wg0B-2nx2A:
7.14
4wg0C-2nx2A:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2nx2 HYPOTHETICAL PROTEIN
YPSA
(Bacillus
subtilis) 		4 / 7 LEU A  65
LEU A  72
LYS A  32
LEU A  35
 None
 0.81A 4wg0L-2nx2A:
undetectable
4wg0M-2nx2A:
undetectable		 4wg0L-2nx2A:
7.14
4wg0M-2nx2A:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2nx2 HYPOTHETICAL PROTEIN
YPSA
(Bacillus
subtilis) 		4 / 6 TYR A 164
GLY A  42
SER A   0
LEU A   1
 None
 1.20A 5bphA-2nx2A:
2.3		 5bphA-2nx2A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2nx2 HYPOTHETICAL PROTEIN
YPSA
(Bacillus
subtilis) 		4 / 4 TYR A 164
GLY A  42
SER A   0
LEU A   1
 None
 1.18A 5bphC-2nx2A:
2.2		 5bphC-2nx2A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2nx2 HYPOTHETICAL PROTEIN
YPSA
(Bacillus
subtilis) 		4 / 6 TYR A 164
GLY A  42
SER A   0
LEU A   1
 None
 1.25A 5bphD-2nx2A:
2.6		 5bphD-2nx2A:
22.45