SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ny0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 2ny0 ENVELOPE
GLYCOPROTEIN GP120
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A 483
ILE A 251
HIS A 249
GLY A 263
 None
 0.75A 3b9lA-2ny0A:
undetectable		 3b9lA-2ny0A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 2ny0 ENVELOPE
GLYCOPROTEIN GP120
(Human
immunodeficiency
virus
1) 		4 / 8 TRP A 375
TRP A 427
PHE A 382
PRO A 212
 None
 1.24A 3v35A-2ny0A:
undetectable		 3v35A-2ny0A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 2ny0 ENVELOPE
GLYCOPROTEIN GP120
(Human
immunodeficiency
virus
1) 		3 / 3 GLN A 203
ASP A 113
GLN A 428
 None
 0.89A 4aztA-2ny0A:
undetectable		 4aztA-2ny0A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2ny0 ENVELOPE
GLYCOPROTEIN GP120
(Human
immunodeficiency
virus
1) 		5 / 12 PHE A 391
ASN A 332
VAL A 292
ILE A 449
LEU A 452
 None
 1.38A 4k39A-2ny0A:
undetectable		 4k39A-2ny0A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2ny0 ENVELOPE
GLYCOPROTEIN GP120
(Human
immunodeficiency
virus
1) 		4 / 5 PHE A 468
ILE A 359
GLN A 352
ARG A 456
 None
 0.80A 5jm4A-2ny0A:
undetectable		 5jm4A-2ny0A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2ny0 ENVELOPE
GLYCOPROTEIN GP120
(Human
immunodeficiency
virus
1) 		4 / 4 PHE A 468
ILE A 359
GLN A 352
ARG A 456
 None
 0.81A 5jm4B-2ny0A:
undetectable		 5jm4B-2ny0A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 2ny0 ENVELOPE
GLYCOPROTEIN GP120
(Human
immunodeficiency
virus
1) 		4 / 6 PHE A 468
LEU A 452
ARG A 469
GLY A 471
 None
 1.10A 5o4yA-2ny0A:
undetectable		 5o4yA-2ny0A:
5.47