SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nya'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 10 LEU A 354
VAL A 351
LEU A 316
LEU A 319
VAL A 174
 None
 1.08A 1cqpA-2nyaA:
undetectable
1cqpB-2nyaA:
3.3		 1cqpA-2nyaA:
12.81
1cqpB-2nyaA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 5 GLU A 572
ARG A 510
LYS A   7
ASP A   6
 None
 1.48A 1k4tA-2nyaA:
undetectable		 1k4tA-2nyaA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 7 VAL A 565
VAL A 527
LEU A 526
LEU A 589
 None
 0.70A 1pthA-2nyaA:
0.2		 1pthA-2nyaA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 7 VAL A 565
VAL A 527
LEU A 526
LEU A 589
 None
 0.70A 1pthB-2nyaA:
0.3		 1pthB-2nyaA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		3 / 3 ASP A 218
PHE A 173
ASN A 200
 None
 0.80A 1sg9B-2nyaA:
undetectable		 1sg9B-2nyaA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 LEU A 663
ASN A 233
ALA A 236
LEU A 356
LEU A 256
 None
 1.28A 1ya3B-2nyaA:
undetectable		 1ya3B-2nyaA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		3 / 3 ASP A 726
VAL A 709
PRO A 706
 None
 0.73A 2avvA-2nyaA:
1.7		 2avvA-2nyaA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 7 LEU A 770
PRO A 775
GLU A 666
ARG A 343
 None
 1.03A 2jn3A-2nyaA:
undetectable		 2jn3A-2nyaA:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 LEU A 663
ASN A 233
ALA A 236
LEU A 356
LEU A 256
 None
 1.21A 2oaxB-2nyaA:
undetectable		 2oaxB-2nyaA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 LEU A 663
ASN A 233
ALA A 236
LEU A 356
LEU A 256
 None
 1.30A 2oaxC-2nyaA:
undetectable		 2oaxC-2nyaA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 LEU A 663
ASN A 233
ALA A 236
LEU A 356
LEU A 256
 None
 1.29A 2oaxD-2nyaA:
undetectable		 2oaxD-2nyaA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 LEU A 663
ASN A 233
ALA A 236
LEU A 356
LEU A 256
 None
 1.22A 2oaxE-2nyaA:
undetectable		 2oaxE-2nyaA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 ALA A  87
LEU A 487
PHE A 529
SER A 530
LEU A 126
 None
 1.14A 2oipB-2nyaA:
undetectable		 2oipB-2nyaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 ALA A  87
LEU A 487
PHE A 529
SER A 530
LEU A 126
 None
 1.17A 2oipD-2nyaA:
undetectable		 2oipD-2nyaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 5 PHE A 508
PHE A 594
TRP A 118
GLY A 379
 None
 1.41A 2qmzA-2nyaA:
undetectable
2qmzB-2nyaA:
2.1		 2qmzA-2nyaA:
15.38
2qmzB-2nyaA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 8 PHE A 533
VAL A 538
TYR A 560
PHE A 127
 None
 1.15A 2wekA-2nyaA:
2.5		 2wekA-2nyaA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 8 PHE A 533
VAL A 538
TYR A 560
PHE A 127
 None
 1.17A 2wekB-2nyaA:
2.5		 2wekB-2nyaA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 GLY A 266
TYR A 265
GLY A 281
LEU A 776
ILE A 263
 None
 1.10A 2y7kD-2nyaA:
undetectable		 2y7kD-2nyaA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		3 / 3 PHE A 758
ASN A 766
PHE A 782
 MGD  A3001 (-3.9A)
MGD  A3001 (-2.8A)
MGD  A3001 (-3.6A)
 0.72A 2zbuD-2nyaA:
2.9		 2zbuD-2nyaA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 6 LEU A 302
GLN A 318
LEU A 316
GLU A 317
 None
 1.14A 3h5gB-2nyaA:
undetectable
3h5gC-2nyaA:
undetectable		 3h5gB-2nyaA:
3.90
3h5gC-2nyaA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 TYR A 352
GLY A 150
ALA A 147
SER A 777
ASP A 283
 None
 1.06A 3id6C-2nyaA:
undetectable		 3id6C-2nyaA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 8 ASN A 348
LEU A 354
SER A 332
ASN A 339
 None
 1.12A 3kp2A-2nyaA:
undetectable
3kp2B-2nyaA:
undetectable		 3kp2A-2nyaA:
10.39
3kp2B-2nyaA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 8 ASN A  40
GLY A  18
ALA A  37
ASP A  36
GLY A 619
 None
 1.46A 3so9A-2nyaA:
undetectable		 3so9A-2nyaA:
7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 9 PHE A 155
PHE A 650
ILE A 361
GLY A 367
PHE A 151
 None
 1.42A 3t3rC-2nyaA:
undetectable		 3t3rC-2nyaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 7 THR A 380
GLY A 113
TYR A 499
GLY A  14
THR A  15
 None
None
None
None
SF4  A2001 ( 3.9A)
 1.48A 3tajA-2nyaA:
undetectable		 3tajA-2nyaA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 THR A 489
SER A 472
LEU A 485
VAL A  90
PHE A  88
 MGD  A3001 (-3.6A)
None
None
None
None
 1.33A 3u9fB-2nyaA:
undetectable
3u9fC-2nyaA:
undetectable		 3u9fB-2nyaA:
13.29
3u9fC-2nyaA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 PHE A  88
THR A 489
SER A 472
LEU A 485
VAL A  90
 None
MGD  A3001 (-3.6A)
None
None
None
 1.35A 3u9fJ-2nyaA:
0.0
3u9fL-2nyaA:
0.0		 3u9fJ-2nyaA:
13.29
3u9fL-2nyaA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 11 THR A 489
SER A 472
LEU A 485
VAL A  90
PHE A  88
 MGD  A3001 (-3.6A)
None
None
None
None
 1.39A 3u9fN-2nyaA:
undetectable
3u9fO-2nyaA:
undetectable		 3u9fN-2nyaA:
13.29
3u9fO-2nyaA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 LEU A 663
ASN A 233
ALA A 236
LEU A 356
LEU A 256
 None
 1.26A 3vhuA-2nyaA:
undetectable		 3vhuA-2nyaA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 HIS A 142
GLY A 111
ASN A 447
ALA A 123
PHE A 387
 MGD  A3001 ( 4.9A)
None
None
None
None
 0.81A 3vywB-2nyaA:
2.2		 3vywB-2nyaA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 HIS A 142
GLY A 111
ASN A 447
ALA A 123
PHE A 387
 MGD  A3001 ( 4.9A)
None
None
None
None
 0.79A 3vywC-2nyaA:
2.3		 3vywC-2nyaA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 HIS A 142
GLY A 111
ASN A 447
ALA A 123
PHE A 387
 MGD  A3001 ( 4.9A)
None
None
None
None
 0.79A 3vywD-2nyaA:
2.2		 3vywD-2nyaA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		3 / 3 ASP A 639
GLY A 605
TYR A 634
 None
 0.80A 3w9tC-2nyaA:
undetectable		 3w9tC-2nyaA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		3 / 3 ASP A 639
GLY A 605
TYR A 634
 None
 0.80A 3w9tG-2nyaA:
undetectable		 3w9tG-2nyaA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 6 GLY A 108
ASN A 135
LEU A 437
ASN A 438
 None
 0.96A 3zqtA-2nyaA:
undetectable		 3zqtA-2nyaA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 7 VAL A  39
GLY A  14
THR A 372
PHE A 369
 None
 1.02A 4ejjB-2nyaA:
undetectable		 4ejjB-2nyaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 LEU A 232
ASP A 228
VAL A 351
ALA A 178
LEU A 776
 None
MGD  A4001 (-3.2A)
None
MGD  A4001 ( 4.4A)
None
 1.34A 4iaqA-2nyaA:
undetectable		 4iaqA-2nyaA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 8 ASN A 348
ALA A 147
SER A 146
ARG A 382
 None
 1.14A 4ijiF-2nyaA:
undetectable		 4ijiF-2nyaA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 7 ASN A 348
ALA A 147
SER A 146
ARG A 382
 None
 1.16A 4ijiH-2nyaA:
undetectable		 4ijiH-2nyaA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		3 / 3 LEU A 487
PRO A 488
ARG A 532
 None
 0.60A 4klrB-2nyaA:
1.6		 4klrB-2nyaA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		3 / 3 ASP A 137
ASN A 134
SER A 777
 None
 0.83A 4obwA-2nyaA:
3.2		 4obwA-2nyaA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		3 / 3 ASN A 446
ASP A 473
ASP A  59
 MGD  A3001 (-4.5A)
MGD  A3001 (-2.9A)
None
 0.82A 4obwD-2nyaA:
2.7		 4obwD-2nyaA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 7 VAL A 384
ILE A 136
TRP A 115
LEU A 523
 None
 1.23A 4xo7B-2nyaA:
undetectable		 4xo7B-2nyaA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 5 TYR A 641
GLY A 601
TYR A 651
GLY A 156
 None
 1.03A 5ayfA-2nyaA:
undetectable		 5ayfA-2nyaA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 5 SER A 213
ALA A 181
HIS A 211
LEU A 175
 None
None
MGD  A4001 (-4.2A)
None
 1.41A 5dzkb-2nyaA:
undetectable
5dzkp-2nyaA:
undetectable		 5dzkb-2nyaA:
14.95
5dzkp-2nyaA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 5 SER A 213
ALA A 181
HIS A 211
LEU A 175
 None
None
MGD  A4001 (-4.2A)
None
 1.40A 5dzkc-2nyaA:
undetectable
5dzkq-2nyaA:
undetectable		 5dzkc-2nyaA:
14.95
5dzkq-2nyaA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 GLY A 177
HIS A 184
GLU A 503
ALA A 181
ILE A 331
 MGD  A4001 (-3.6A)
None
None
None
None
 1.20A 5igyA-2nyaA:
undetectable		 5igyA-2nyaA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 7 ASP A 171
PHE A 173
SER A 197
ASN A 198
 None
 1.01A 5l1fC-2nyaA:
undetectable		 5l1fC-2nyaA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 8 PRO A 452
GLU A 457
TRP A 462
TYR A 440
 None
 1.47A 5oh1C-2nyaA:
undetectable		 5oh1C-2nyaA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 7 TYR A 755
GLN A 763
ASP A 760
HIS A 688
 None
 1.44A 5ov9B-2nyaA:
undetectable		 5ov9B-2nyaA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 10 PHE A 131
SER A 133
ALA A 123
LEU A 126
GLY A 130
 None
 1.10A 5oy01-2nyaA:
undetectable
5oy07-2nyaA:
undetectable		 5oy01-2nyaA:
8.36
5oy07-2nyaA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		5 / 12 ALA A 172
LEU A 319
THR A 358
ILE A 239
THR A 202
 None
 1.21A 5z6fA-2nyaA:
undetectable		 5z6fA-2nyaA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 2nya PERIPLASMIC NITRATE
REDUCTASE
(Escherichia
coli) 		4 / 8 LEU A 544
GLU A 549
THR A 535
ASN A 411
 None
 1.16A 6c71B-2nyaA:
undetectable		 6c71B-2nyaA:
8.82