SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nyh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 2nyh PUTATIVE DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 12 PHE A  85
LEU A 110
ALA A 101
PRO A  88
THR A  90
 None
 1.28A 1mx8A-2nyhA:
undetectable		 1mx8A-2nyhA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 2nyh PUTATIVE DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 10 ALA A 101
ALA A  14
LEU A  61
LEU A  75
LEU A 110
 None
 1.17A 2bxqA-2nyhA:
undetectable		 2bxqA-2nyhA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2nyh PUTATIVE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 ARG A  23
THR A  28
TRP A  27
 None
 1.10A 4d7hA-2nyhA:
undetectable		 4d7hA-2nyhA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2nyh PUTATIVE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 ARG A  23
THR A  28
TRP A  27
 None
 1.19A 4ug5A-2nyhA:
undetectable		 4ug5A-2nyhA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 2nyh PUTATIVE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 ARG A  23
THR A  28
TRP A  27
 None
 1.09A 4uglA-2nyhA:
undetectable		 4uglA-2nyhA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2nyh PUTATIVE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 ARG A  23
THR A  28
TRP A  27
 None
 1.10A 5g6cA-2nyhA:
undetectable		 5g6cA-2nyhA:
15.92