SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nyz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		4 / 8 THR A 183
LEU A  65
VAL A 153
VAL A 110
 None
 0.88A 1t86A-2nyzA:
undetectable		 1t86A-2nyzA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		3 / 3 ALA A 206
VAL A  74
TRP A  76
 None
 0.70A 1tkqA-2nyzA:
undetectable		 1tkqA-2nyzA:
3.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		3 / 3 ASN A 102
TYR A 300
SER A 313
 None
 0.90A 2gvcB-2nyzA:
undetectable		 2gvcB-2nyzA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		3 / 3 ASN A 102
TYR A 300
SER A 313
 None
 0.88A 2gvcE-2nyzA:
undetectable		 2gvcE-2nyzA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		5 / 12 ALA A 257
LEU A 284
THR A  18
VAL A  16
GLY A  15
 None
 1.08A 2ve3A-2nyzA:
undetectable		 2ve3A-2nyzA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		4 / 7 TYR A 125
VAL A 128
TYR A 127
ILE A  86
 None
 1.28A 2xz5B-2nyzA:
undetectable
2xz5E-2nyzA:
undetectable		 2xz5B-2nyzA:
19.77
2xz5E-2nyzA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		4 / 8 SER A 113
GLN A 176
PHE A 173
TRP A  76
 None
 1.12A 3n62A-2nyzA:
undetectable		 3n62A-2nyzA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		4 / 8 SER A 113
GLN A 176
PHE A 173
TRP A  76
 None
 1.23A 3n66B-2nyzA:
undetectable		 3n66B-2nyzA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		4 / 5 ALA A  34
GLU A  41
ALA A  40
MET A 155
 None
 1.35A 3r9tC-2nyzA:
undetectable		 3r9tC-2nyzA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		4 / 7 THR A 183
LEU A  65
VAL A 153
VAL A 110
 None
 0.88A 4cp4A-2nyzA:
undetectable		 4cp4A-2nyzA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		4 / 7 SER A 113
GLN A 176
PHE A 173
TRP A  76
 None
 1.24A 4kcnB-2nyzA:
undetectable		 4kcnB-2nyzA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		4 / 7 LEU A 281
PRO A 338
LYS A 267
TYR A 266
 None
 1.09A 4lb2A-2nyzA:
undetectable		 4lb2A-2nyzA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		3 / 3 MET A 322
GLN A 372
TYR A 374
 None
 1.02A 4udcA-2nyzA:
undetectable		 4udcA-2nyzA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		5 / 11 VAL A 110
PHE A 173
GLY A 199
GLY A  73
GLU A 197
 None
 1.48A 4zvmA-2nyzA:
undetectable
4zvmB-2nyzA:
undetectable		 4zvmA-2nyzA:
22.10
4zvmB-2nyzA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		5 / 12 LEU A  55
ILE A  26
GLU A 197
THR A 183
LEU A  65
 None
 1.13A 5ienA-2nyzA:
undetectable		 5ienA-2nyzA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		5 / 12 LEU A  55
ILE A  26
GLU A 197
THR A 183
LEU A  65
 None
 1.03A 5ienB-2nyzA:
undetectable		 5ienB-2nyzA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2nyz HYPOTHETICAL PROTEIN
GAMMAHV.M3
(Murid
gammaherpesvirus
4) 		4 / 8 SER A 113
GLN A 176
PHE A 173
TRP A  76
 None
 1.25A 5vunB-2nyzA:
undetectable		 5vunB-2nyzA:
22.95