SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nzo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.17A 2wa2B-2nzoA:
undetectable		 2wa2B-2nzoA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		5 / 9 LEU A  59
VAL A  18
ILE A  43
ALA A  20
ILE A  17
 None
 0.97A 3el0B-2nzoA:
undetectable		 3el0B-2nzoA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		5 / 12 GLY A  15
GLY A 106
THR A  14
ASP A  36
ILE A  35
 None
 1.00A 3eluA-2nzoA:
undetectable		 3eluA-2nzoA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.20A 3elwA-2nzoA:
undetectable		 3elwA-2nzoA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		5 / 12 GLY A  15
GLY A 106
THR A  14
ASP A  36
ILE A  35
 None
 0.95A 3embA-2nzoA:
undetectable		 3embA-2nzoA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		5 / 12 GLY A  15
GLY A 106
THR A  14
ASP A  36
ILE A  35
 None
 0.97A 3gczA-2nzoA:
undetectable		 3gczA-2nzoA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.14A 3p97C-2nzoA:
undetectable		 3p97C-2nzoA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		4 / 8 ILE A  88
GLY A  90
SER A  47
GLN A  49
 None
 0.85A 4acbB-2nzoA:
2.3
4acbC-2nzoA:
2.4		 4acbB-2nzoA:
14.32
4acbC-2nzoA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.14A 4ctjC-2nzoA:
undetectable		 4ctjC-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.12A 4ctkC-2nzoA:
undetectable		 4ctkC-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.13A 5e9qC-2nzoA:
undetectable		 5e9qC-2nzoA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.13A 5ec8C-2nzoA:
undetectable		 5ec8C-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.13A 5ehgC-2nzoA:
undetectable		 5ehgC-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		5 / 12 GLY A  15
GLY A 106
THR A  14
ASP A  36
ILE A  35
 None
 0.96A 5ehiA-2nzoA:
undetectable		 5ehiA-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		5 / 12 GLY A  15
GLY A 106
THR A  14
ASP A  36
ILE A  35
 None
 0.98A 5ehiC-2nzoA:
undetectable		 5ehiC-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.12A 5eifA-2nzoA:
undetectable		 5eifA-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.14A 5eifC-2nzoA:
undetectable		 5eifC-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		5 / 12 GLY A  15
GLY A 106
THR A  14
ASP A  36
ILE A  35
 None
 0.96A 5eiwA-2nzoA:
undetectable		 5eiwA-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.11A 5eiwC-2nzoA:
undetectable		 5eiwC-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		5 / 12 GLY A  15
GLY A 106
THR A  14
ASP A  36
ILE A  35
 None
 0.97A 5ekxA-2nzoA:
undetectable		 5ekxA-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.12A 5ekxB-2nzoA:
undetectable		 5ekxB-2nzoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		6 / 12 GLY A  15
GLY A 106
THR A  14
VAL A  64
ASP A  36
ILE A  35
 None
 1.14A 5njvB-2nzoA:
undetectable		 5njvB-2nzoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 2nzo PROTEIN CSAA
(Bacillus
subtilis) 		5 / 12 GLY A  15
GLY A 106
THR A  14
ASP A  36
ILE A  35
 None
 0.98A 5njvD-2nzoA:
undetectable		 5njvD-2nzoA:
20.91