SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 2o01 PSI LIGHT-HARVESTING
ANTENNA CHLOROPHYLL
A/B-BINDING PROTEIN
(Pisum
sativum) 		5 / 11 GLY 4 177
PRO 4 178
GLY 4 166
GLN 4 170
LEU 4 162
 None
None
CLA  44003 ( 3.8A)
CLA  44003 (-3.1A)
CLA  44003 (-4.7A)
 1.24A 1jzsA-2o014:
undetectable		 1jzsA-2o014:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 2o01 PHOTOSYSTEM I
IRON-SULFUR CENTER
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IV A,
CHLOROPLAST
(Arabidopsis
thaliana;
Pisum
sativum) 		4 / 8 PHE C  62
TYR E  82
TYR E  63
TRP E  45
 None
 1.46A 2aoxA-2o01C:
undetectable		 2aoxA-2o01C:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 2o01 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 8 PHE L 143
LEU L  95
LEU L  64
LEU L  63
 None
None
None
CLA  L1502 (-4.2A)
 1.01A 2bfpB-2o01L:
undetectable		 2bfpB-2o01L:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 2o01 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 5 TYR L 159
ALA L  88
ALA L  80
TYR L  79
 None
 1.12A 3d91A-2o01L:
undetectable		 3d91A-2o01L:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2o01 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI,
CHLOROPLAST
(Spinacia
oleracea) 		5 / 11 PHE L 143
GLY L  53
ALA L  59
GLY L 146
ALA L  71
 None
None
CLA  L1502 ( 3.3A)
None
None
 1.21A 4l6v1-2o01L:
undetectable
4l6v6-2o01L:
undetectable		 4l6v1-2o01L:
14.98
4l6v6-2o01L:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2o01 PSI LIGHT-HARVESTING
ANTENNA CHLOROPHYLL
A/B-BINDING PROTEIN
(Pisum
sativum) 		5 / 12 GLU 4 102
ILE 4 103
GLN 4  42
ILE 4 109
PHE 4  40
 CLA  44012 (-2.9A)
CLA  41304 (-4.1A)
CLA  44011 (-2.9A)
None
None
 1.00A 4zvmA-2o014:
undetectable
4zvmB-2o014:
undetectable		 4zvmA-2o014:
22.73
4zvmB-2o014:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 2o01 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI,
CHLOROPLAST
(Spinacia
oleracea) 		5 / 12 LEU L  58
GLY L 142
GLY L 146
GLU L  55
LEU L  51
 CLA  H1501 (-3.8A)
None
None
CLA  L1502 ( 3.4A)
None
 0.96A 6ectA-2o01L:
undetectable		 6ectA-2o01L:
18.89