SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o0h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 2o0h DNA PACKAGING
PROTEIN GP17
(Escherichia
virus
T4) 		4 / 7 VAL A 157
LEU A 164
LEU A 147
ILE A 284
 None
 0.91A 3gp0A-2o0hA:
undetectable		 3gp0A-2o0hA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 2o0h DNA PACKAGING
PROTEIN GP17
(Escherichia
virus
T4) 		4 / 7 GLU A 208
ASP A 201
GLN A 205
ILE A 226
 None
 1.13A 4ii8A-2o0hA:
undetectable		 4ii8A-2o0hA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 2o0h DNA PACKAGING
PROTEIN GP17
(Escherichia
virus
T4) 		3 / 3 LEU A  90
LEU A 228
ASN A 222
 None
 0.75A 4otwA-2o0hA:
undetectable		 4otwA-2o0hA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 2o0h DNA PACKAGING
PROTEIN GP17
(Escherichia
virus
T4) 		3 / 3 TRP A 221
GLU A 208
ASP A 201
 None
 0.99A 5gqbA-2o0hA:
undetectable		 5gqbA-2o0hA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 2o0h DNA PACKAGING
PROTEIN GP17
(Escherichia
virus
T4) 		5 / 12 LEU A 200
VAL A 178
LEU A  93
ILE A 218
LEU A 228
 None
 1.09A 5ienA-2o0hA:
undetectable		 5ienA-2o0hA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2o0h DNA PACKAGING
PROTEIN GP17
(Escherichia
virus
T4) 		5 / 12 ALA A 171
LEU A 174
ALA A 175
PHE A 120
LEU A 210
 None
 1.02A 5k9dA-2o0hA:
undetectable		 5k9dA-2o0hA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2o0h DNA PACKAGING
PROTEIN GP17
(Escherichia
virus
T4) 		5 / 12 SER A 336
SER A 161
THR A 287
LEU A 345
LEU A  21
 None
 1.37A 6a93B-2o0hA:
undetectable		 6a93B-2o0hA:
21.45