SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o1a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2o1a IRON-REGULATED
SURFACE DETERMINANT
PROTEIN A
(Staphylococcus
aureus) 		3 / 3 LYS A  35
ASP A  92
ASP A  40
 None
 0.89A 2br4D-2o1aA:
undetectable		 2br4D-2o1aA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 2o1a IRON-REGULATED
SURFACE DETERMINANT
PROTEIN A
(Staphylococcus
aureus) 		5 / 12 LEU A 128
THR A 109
PHE A  57
LEU A  61
ILE A  96
 None
 1.17A 2ydoA-2o1aA:
undetectable		 2ydoA-2o1aA:
18.09