SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 2o1m PROBABLE AMINO-ACID
ABC TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YTMK
(Bacillus
subtilis) 		3 / 3 THR A 232
GLU A  44
ASP A  33
 None
 0.78A 1nt2A-2o1mA:
undetectable		 1nt2A-2o1mA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_D_FOLD270_0
(PTERIDINE REDUCTASE)		 2o1m PROBABLE AMINO-ACID
ABC TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YTMK
(Bacillus
subtilis) 		5 / 12 ARG A  90
CYH A  30
PHE A  26
VAL A  80
GLU A  64
 SO4  A 401 (-3.9A)
None
None
None
None
 1.44A 3bmcD-2o1mA:
0.9		 3bmcD-2o1mA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 2o1m PROBABLE AMINO-ACID
ABC TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YTMK
(Bacillus
subtilis) 		3 / 3 GLN A 166
THR A 163
LEU A 123
 None
 0.72A 3ondA-2o1mA:
undetectable		 3ondA-2o1mA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 2o1m PROBABLE AMINO-ACID
ABC TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YTMK
(Bacillus
subtilis) 		3 / 3 GLN A 166
THR A 163
LEU A 123
 None
 0.72A 3ondB-2o1mA:
undetectable		 3ondB-2o1mA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2o1m PROBABLE AMINO-ACID
ABC TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YTMK
(Bacillus
subtilis) 		4 / 8 ILE A  46
ILE A  18
PHE A  58
LEU A  72
 None
 0.85A 3ua5A-2o1mA:
undetectable		 3ua5A-2o1mA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 2o1m PROBABLE AMINO-ACID
ABC TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YTMK
(Bacillus
subtilis) 		4 / 5 THR A 190
ILE A 191
LYS A 192
GLU A 193
 None
 1.18A 4ac9C-2o1mA:
undetectable		 4ac9C-2o1mA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2o1m PROBABLE AMINO-ACID
ABC TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YTMK
(Bacillus
subtilis) 		4 / 5 THR A 190
ILE A 191
LYS A 192
GLU A 193
 None
 1.15A 4acaC-2o1mA:
undetectable		 4acaC-2o1mA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2o1m PROBABLE AMINO-ACID
ABC TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YTMK
(Bacillus
subtilis) 		4 / 5 THR A 190
ILE A 191
LYS A 192
GLU A 193
 None
 1.15A 4acbC-2o1mA:
undetectable		 4acbC-2o1mA:
19.67