SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DTT_E_H4BE1004_1 (HYPOTHETICAL PROTEIN PH0634)	2o1q	PUTATIVE ACETYL/PROPIONYL-COA CARBOXYLASE, ALPHA SUBUNIT (Methylibium petroleiphilum)	5 / 11	TYR A 113 PHE A 48 HIS A 61 HIS A 101 HIS A 59	None None ZN A 145 ( 3.3A) ZN A 145 ( 2.8A) ZN A 145 ( 3.2A)	1.34A	2dttD-2o1qA: undetectable 2dttE-2o1qA: undetectable	2dttD-2o1qA: 20.81 2dttE-2o1qA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_B_ACTB600_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	2o1q	PUTATIVE ACETYL/PROPIONYL-COA CARBOXYLASE, ALPHA SUBUNIT (Methylibium petroleiphilum)	4 / 5	HIS A 61 ALA A 99 GLU A 95 HIS A 101	ZN A 145 ( 3.3A) None None ZN A 145 ( 2.8A)	1.41A	3mbgB-2o1qA: undetectable 3mbgC-2o1qA: undetectable	3mbgB-2o1qA: 21.30 3mbgC-2o1qA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_C_ACTC600_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	2o1q	PUTATIVE ACETYL/PROPIONYL-COA CARBOXYLASE, ALPHA SUBUNIT (Methylibium petroleiphilum)	4 / 5	GLU A 95 HIS A 101 HIS A 61 ALA A 99	None ZN A 145 ( 2.8A) ZN A 145 ( 3.3A) None	1.43A	3mbgB-2o1qA: undetectable 3mbgC-2o1qA: undetectable	3mbgB-2o1qA: 21.30 3mbgC-2o1qA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_C_9PLC501_1 (CYTOCHROME P450 2E1)	2o1q	PUTATIVE ACETYL/PROPIONYL-COA CARBOXYLASE, ALPHA SUBUNIT (Methylibium petroleiphilum)	4 / 5	PHE A 116 PHE A 112 THR A 104 LEU A 120	None ACT A 149 ( 4.6A) ACT A 149 (-2.6A) None	1.20A	3t3zC-2o1qA: undetectable	3t3zC-2o1qA: 15.09

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2DTT_E_H4BE1004_1","HYPOTHETICAL PROTEIN PH0634;HYPOTHETICAL PROTEIN PH0634","2o1q","PUTATIVE ACETYL\/PROPIONYL-COA CARBOXYLASE, ALPHA SUBUNIT","Methylibium petroleiphilum",5,"TYR A 113;PHE A  48;HIS A  61;HIS A 101;HIS A  59","None;None; ZN A 145 ( 3.3A); ZN A 145 ( 2.8A); ZN A 145 ( 3.2A)","1.34A","2dttD-2o1qA:undetectable;2dttE-2o1qA:undetectable","2dttD-2o1qA:20.81;2dttE-2o1qA:20.81"],["3MBG_B_ACTB600_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","2o1q","PUTATIVE ACETYL\/PROPIONYL-COA CARBOXYLASE, ALPHA SUBUNIT","Methylibium petroleiphilum",4,"HIS A  61;ALA A  99;GLU A  95;HIS A 101"," ZN A 145 ( 3.3A);None;None; ZN A 145 ( 2.8A)","1.41A","3mbgB-2o1qA:undetectable;3mbgC-2o1qA:undetectable","3mbgB-2o1qA:21.30;3mbgC-2o1qA:21.30"],["3MBG_C_ACTC600_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","2o1q","PUTATIVE ACETYL\/PROPIONYL-COA CARBOXYLASE, ALPHA SUBUNIT","Methylibium petroleiphilum",4,"GLU A  95;HIS A 101;HIS A  61;ALA A  99","None; ZN A 145 ( 2.8A); ZN A 145 ( 3.3A);None","1.43A","3mbgB-2o1qA:undetectable;3mbgC-2o1qA:undetectable","3mbgB-2o1qA:21.30;3mbgC-2o1qA:21.30"],["3T3Z_C_9PLC501_1","CYTOCHROME P450 2E1","2o1q","PUTATIVE ACETYL\/PROPIONYL-COA CARBOXYLASE, ALPHA SUBUNIT","Methylibium petroleiphilum",4,"PHE A 116;PHE A 112;THR A 104;LEU A 120","None;ACT A 149 ( 4.6A);ACT A 149 (-2.6A);None","1.20A","3t3zC-2o1qA:undetectable","3t3zC-2o1qA:15.09"]]