SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 563
ASN A 570
ASN A 584
VAL A 530
LEU A 538
 None
 1.13A 1r30A-2o1sA:
undetectable		 1r30A-2o1sA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 563
ASN A 570
ASN A 584
VAL A 530
LEU A 538
 None
 1.13A 1r30B-2o1sA:
undetectable		 1r30B-2o1sA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 11 GLY A 158
ALA A 160
PHE A 161
PHE A 277
LEU A 246
 None
 0.93A 1ukbA-2o1sA:
undetectable		 1ukbA-2o1sA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 TYR A 392
TYR A 476
LEU A 329
MET A 352
 None
 1.43A 1uw6A-2o1sA:
undetectable
1uw6B-2o1sA:
undetectable		 1uw6A-2o1sA:
15.94
1uw6B-2o1sA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 TYR A 392
TYR A 476
LEU A 329
MET A 352
 None
 1.45A 1uw6D-2o1sA:
undetectable
1uw6E-2o1sA:
undetectable		 1uw6D-2o1sA:
15.94
1uw6E-2o1sA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 TYR A 392
TYR A 476
LEU A 329
MET A 352
 None
 1.46A 1uw6G-2o1sA:
undetectable
1uw6H-2o1sA:
undetectable		 1uw6G-2o1sA:
15.94
1uw6H-2o1sA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 TYR A 392
TYR A 476
LEU A 329
MET A 352
 None
 1.45A 1uw6P-2o1sA:
undetectable
1uw6Q-2o1sA:
undetectable		 1uw6P-2o1sA:
15.94
1uw6Q-2o1sA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 LEU A 329
MET A 352
TYR A 392
TYR A 476
 None
 1.43A 1uw6P-2o1sA:
undetectable
1uw6T-2o1sA:
undetectable		 1uw6P-2o1sA:
15.94
1uw6T-2o1sA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 6 TRP A 618
PRO A 581
LEU A 573
GLY A 566
 None
 1.14A 2hs2B-2o1sA:
undetectable		 2hs2B-2o1sA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		3 / 3 HIS A  85
ILE A  87
LEU A 104
 None
 0.73A 2kceA-2o1sA:
undetectable		 2kceA-2o1sA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		3 / 3 ARG A 601
GLU A 598
GLN A 597
 None
 0.98A 2p16A-2o1sA:
undetectable		 2p16A-2o1sA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 4 LEU A 437
ASP A 539
VAL A 569
THR A 555
 None
 1.27A 3cyxB-2o1sA:
undetectable		 3cyxB-2o1sA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 ILE A 423
GLY A 422
GLY A 433
PRO A 477
ALA A 560
 None
 0.87A 3jb2A-2o1sA:
3.3		 3jb2A-2o1sA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 9 ASP A  77
ALA A 154
ASP A 152
GLY A 158
ILE A 150
 None
TDP  A3001 (-3.6A)
MG  A1001 ( 2.7A)
None
None
 1.01A 3nu4A-2o1sA:
undetectable		 3nu4A-2o1sA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 9 ASP A  77
ALA A 154
ASP A 152
GLY A 158
ILE A 150
 None
TDP  A3001 (-3.6A)
MG  A1001 ( 2.7A)
None
None
 1.00A 3nuoA-2o1sA:
undetectable		 3nuoA-2o1sA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 LEU A 506
ILE A 508
ASN A 510
ILE A 585
 None
 0.87A 3wxoA-2o1sA:
undetectable		 3wxoA-2o1sA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 PHE A 277
ASN A 268
LEU A 262
ILE A 280
LEU A 178
 None
 1.36A 4k39A-2o1sA:
undetectable		 4k39A-2o1sA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 8 ASP A  77
ALA A 154
ASP A 152
VAL A 176
ILE A 150
 None
TDP  A3001 (-3.6A)
MG  A1001 ( 2.7A)
None
None
 1.43A 4ll3A-2o1sA:
undetectable		 4ll3A-2o1sA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 242
ASN A 165
ALA A 160
ILE A 155
ILE A 127
 None
 1.08A 4o2bB-2o1sA:
undetectable		 4o2bB-2o1sA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 566
ALA A 565
GLY A 564
LEU A 437
LEU A 587
 None
 0.63A 4o3fA-2o1sA:
2.8		 4o3fA-2o1sA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 151
ILE A 280
GLN A  81
LEU A  59
THR A 282
 TDP  A3001 (-3.2A)
None
None
None
None
 0.95A 4o5fA-2o1sA:
undetectable
4o5fB-2o1sA:
2.0		 4o5fA-2o1sA:
19.74
4o5fB-2o1sA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLN A  81
LEU A  59
THR A 282
GLY A 151
ILE A 280
 None
None
None
TDP  A3001 (-3.2A)
None
 0.97A 4o5fA-2o1sA:
undetectable
4o5fB-2o1sA:
undetectable		 4o5fA-2o1sA:
19.74
4o5fB-2o1sA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 LEU A 506
VAL A 521
TRP A 618
LEU A 619
 None
 1.12A 4pwdC-2o1sA:
undetectable		 4pwdC-2o1sA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 10 ASP A  77
ALA A 154
ASP A 152
GLY A 158
ILE A 150
 None
TDP  A3001 (-3.6A)
MG  A1001 ( 2.7A)
None
None
 1.03A 4q1wB-2o1sA:
undetectable		 4q1wB-2o1sA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		3 / 3 LEU A 404
ASP A 401
TYR A 400
 None
 0.64A 4qc6B-2o1sA:
undetectable		 4qc6B-2o1sA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 VAL A  78
ALA A 154
LEU A 178
ASN A 179
PHE A 277
 None
TDP  A3001 (-3.6A)
None
None
None
 1.48A 4qdcA-2o1sA:
0.0		 4qdcA-2o1sA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 11 ASP A  77
ALA A 154
ASP A 152
GLY A 158
ILE A 150
 None
TDP  A3001 (-3.6A)
MG  A1001 ( 2.7A)
None
None
 0.98A 4rvjA-2o1sA:
undetectable		 4rvjA-2o1sA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 11 ASP A  77
ALA A 154
ASP A 152
GLY A 158
ILE A 150
 None
TDP  A3001 (-3.6A)
MG  A1001 ( 2.7A)
None
None
 0.99A 4rvjC-2o1sA:
undetectable		 4rvjC-2o1sA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 7 THR A  17
LEU A  20
THR A  69
THR A  60
 None
 0.92A 4z90A-2o1sA:
undetectable
4z90B-2o1sA:
undetectable
4z90C-2o1sA:
undetectable
4z90D-2o1sA:
undetectable
4z90E-2o1sA:
undetectable		 4z90A-2o1sA:
19.04
4z90B-2o1sA:
19.04
4z90C-2o1sA:
19.04
4z90D-2o1sA:
19.04
4z90E-2o1sA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 151
ILE A 280
GLN A  81
LEU A  59
THR A 282
 TDP  A3001 (-3.2A)
None
None
None
None
 0.94A 5b8hA-2o1sA:
2.4
5b8hB-2o1sA:
2.9		 5b8hA-2o1sA:
19.13
5b8hB-2o1sA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLN A  81
LEU A  59
THR A 282
GLY A 151
ILE A 280
 None
None
None
TDP  A3001 (-3.2A)
None
 0.96A 5b8hA-2o1sA:
2.4
5b8hB-2o1sA:
2.9		 5b8hA-2o1sA:
19.13
5b8hB-2o1sA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 242
ASN A 165
ALA A 160
ILE A 155
ILE A 127
 None
 0.97A 5itzB-2o1sA:
undetectable		 5itzB-2o1sA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 THR A  56
ALA A 367
SER A 126
ILE A 127
MET A 164
 None
 1.39A 5iwuA-2o1sA:
undetectable		 5iwuA-2o1sA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 ILE A 423
LEU A 587
GLU A 599
GLY A 595
GLY A 425
 None
 1.00A 5l6eA-2o1sA:
undetectable		 5l6eA-2o1sA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 242
ASN A 165
ALA A 160
ILE A 155
ILE A 127
 None
 1.09A 5mioB-2o1sA:
undetectable		 5mioB-2o1sA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 242
ASN A 165
ALA A 160
ILE A 155
ILE A 127
 None
 1.01A 5xiwB-2o1sA:
undetectable		 5xiwB-2o1sA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		3 / 3 LEU A  28
THR A  69
ASN A  68
 None
 0.71A 6baaE-2o1sA:
undetectable		 6baaE-2o1sA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		3 / 3 LEU A  28
THR A  69
ASN A  68
 None
 0.71A 6baaF-2o1sA:
undetectable		 6baaF-2o1sA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		3 / 3 LEU A  28
THR A  69
ASN A  68
 None
 0.71A 6baaG-2o1sA:
undetectable		 6baaG-2o1sA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		3 / 3 LEU A  28
THR A  69
ASN A  68
 None
 0.70A 6baaH-2o1sA:
undetectable		 6baaH-2o1sA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 6 THR A  60
LEU A  59
THR A  17
LEU A  28
 None
 1.20A 6mvxA-2o1sA:
undetectable
6mvxB-2o1sA:
2.8
6mvxC-2o1sA:
2.9		 6mvxA-2o1sA:
18.59
6mvxB-2o1sA:
18.59
6mvxC-2o1sA:
18.59