SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o2x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		6 / 12 LEU A  33
GLY A  71
ALA A  70
PRO A  62
ALA A  63
ILE A 208
 None
 1.43A 2nmzB-2o2xA:
undetectable		 2nmzB-2o2xA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 ARG A  37
ILE A  83
TRP A  90
PHE A  93
 None
 1.47A 2nsiA-2o2xA:
undetectable
2nsiB-2o2xA:
undetectable		 2nsiA-2o2xA:
19.82
2nsiB-2o2xA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 TRP A  90
PHE A  93
ARG A  37
ILE A  83
 None
 1.48A 2nsiA-2o2xA:
undetectable
2nsiB-2o2xA:
undetectable		 2nsiA-2o2xA:
19.82
2nsiB-2o2xA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 ARG A  37
ILE A  83
TRP A  90
PHE A  93
 None
 1.44A 2nsiC-2o2xA:
undetectable
2nsiD-2o2xA:
undetectable		 2nsiC-2o2xA:
19.82
2nsiD-2o2xA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 TRP A  90
PHE A  93
ARG A  37
ILE A  83
 None
 1.45A 2nsiC-2o2xA:
undetectable
2nsiD-2o2xA:
undetectable		 2nsiC-2o2xA:
19.82
2nsiD-2o2xA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		5 / 12 LEU A  35
GLY A 177
GLN A 176
MET A  60
MET A 166
 None
 1.12A 2yhdA-2o2xA:
undetectable		 2yhdA-2o2xA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		5 / 12 LEU A  35
LEU A 157
GLY A 177
GLN A 176
MET A 166
 None
 1.13A 2yhdA-2o2xA:
undetectable		 2yhdA-2o2xA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		5 / 11 LEU A  35
LEU A 157
GLN A 176
LEU A 195
MET A 166
 None
 1.11A 2ylpA-2o2xA:
undetectable		 2ylpA-2o2xA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 TRP A  90
PHE A  93
ARG A  37
ILE A  83
 None
 1.49A 3e7gA-2o2xA:
undetectable
3e7gB-2o2xA:
undetectable		 3e7gA-2o2xA:
21.45
3e7gB-2o2xA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 ARG A  37
ILE A  83
TRP A  90
PHE A  93
 None
 1.49A 3e7gC-2o2xA:
undetectable
3e7gD-2o2xA:
undetectable		 3e7gC-2o2xA:
21.45
3e7gD-2o2xA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_A_H4BA1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 ARG A  37
ILE A  83
TRP A  90
PHE A  93
 None
 1.45A 3ej8A-2o2xA:
0.0
3ej8B-2o2xA:
0.0		 3ej8A-2o2xA:
21.20
3ej8B-2o2xA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_D_H4BD4902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 TRP A  90
PHE A  93
ARG A  37
ILE A  83
 None
 1.45A 3ej8C-2o2xA:
0.0
3ej8D-2o2xA:
0.0		 3ej8C-2o2xA:
21.20
3ej8D-2o2xA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 ASP A  44
TYR A  87
PRO A  48
ARG A  85
 GOL  A 219 (-3.1A)
None
None
None
 0.96A 3s3oA-2o2xA:
undetectable		 3s3oA-2o2xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		3 / 3 LEU A 174
MET A 166
ASP A  36
 None
 0.72A 3v5wA-2o2xA:
undetectable		 3v5wA-2o2xA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 TRP A  90
PHE A  93
ARG A  37
ILE A  83
 None
 1.44A 4cx7C-2o2xA:
undetectable
4cx7D-2o2xA:
undetectable		 4cx7C-2o2xA:
19.82
4cx7D-2o2xA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 7 TRP A  90
PHE A  93
ARG A  37
ILE A  83
 None
 1.42A 4nosA-2o2xA:
undetectable
4nosB-2o2xA:
undetectable		 4nosA-2o2xA:
21.53
4nosB-2o2xA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		5 / 10 LEU A 204
LEU A 205
GLY A 202
SER A 198
ILE A 208
 None
 1.16A 4xj7C-2o2xA:
2.9
4xj7D-2o2xA:
2.9		 4xj7C-2o2xA:
23.81
4xj7D-2o2xA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		3 / 3 LEU A 157
LEU A 204
ARG A  37
 None
 0.62A 5hnzB-2o2xA:
3.8		 5hnzB-2o2xA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 5 ALA A 116
VAL A  76
PHE A  93
ILE A  41
 None
 0.93A 5of1B-2o2xA:
undetectable		 5of1B-2o2xA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 8 ASP A 112
ILE A  21
ARG A  20
ARG A  24
 None
 1.19A 6hisA-2o2xA:
undetectable
6hisB-2o2xA:
undetectable		 6hisA-2o2xA:
16.20
6hisB-2o2xA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 8 ASP A 112
ILE A  21
ARG A  20
ARG A  24
 None
 1.19A 6hisB-2o2xA:
undetectable
6hisC-2o2xA:
undetectable		 6hisB-2o2xA:
16.20
6hisC-2o2xA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 8 ASP A 112
ILE A  21
ARG A  20
ARG A  24
 None
 1.19A 6hisC-2o2xA:
undetectable
6hisD-2o2xA:
undetectable		 6hisC-2o2xA:
16.20
6hisD-2o2xA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 8 ASP A 112
ILE A  21
ARG A  20
ARG A  24
 None
 1.19A 6hisD-2o2xA:
undetectable
6hisE-2o2xA:
undetectable		 6hisD-2o2xA:
16.20
6hisE-2o2xA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		4 / 8 ASP A 112
ILE A  21
ARG A  20
ARG A  24
 None
 1.19A 6hisA-2o2xA:
undetectable
6hisE-2o2xA:
undetectable		 6hisA-2o2xA:
16.20
6hisE-2o2xA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 2o2x HYPOTHETICAL PROTEIN
(Mesorhizobium
loti) 		5 / 9 TRP A  17
GLU A  19
VAL A  96
ILE A  54
MET A  60
 None
 1.49A 6hloA-2o2xA:
4.8		 6hloA-2o2xA:
18.43