SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o2z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 LEU A 123
PRO A 124
LEU A 168
 None
 0.54A 1hrkA-2o2zA:
3.1		 1hrkA-2o2zA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 8 VAL A  60
VAL A   6
VAL A   8
LEU A  19
 None
 0.87A 1igxA-2o2zA:
undetectable		 1igxA-2o2zA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 12 GLU A 135
ARG A 157
ILE A 155
ILE A 148
ALA A 151
 None
 1.24A 1kijB-2o2zA:
undetectable		 1kijB-2o2zA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A 249
LEU A 250
HIS A 252
ALA A 230
HIS A 301
 None
None
None
None
NAD  A 400 (-3.6A)
 1.26A 2a58A-2o2zA:
3.1
2a58B-2o2zA:
3.1		 2a58A-2o2zA:
20.12
2a58B-2o2zA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A 249
LEU A 250
HIS A 252
ALA A 230
HIS A 301
 None
None
None
None
NAD  A 400 (-3.6A)
 1.28A 2a58B-2o2zA:
3.1
2a58C-2o2zA:
undetectable		 2a58B-2o2zA:
20.12
2a58C-2o2zA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A 249
LEU A 250
HIS A 252
ALA A 230
HIS A 301
 None
None
None
None
NAD  A 400 (-3.6A)
 1.26A 2a58D-2o2zA:
undetectable
2a58E-2o2zA:
3.1		 2a58D-2o2zA:
20.12
2a58E-2o2zA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 12 LEU A 132
ILE A 148
ILE A 155
LEU A 188
SER A 187
 None
None
None
None
SO4  A 324 ( 3.5A)
 0.86A 2bdmA-2o2zA:
undetectable		 2bdmA-2o2zA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 7 ILE A 215
ILE A 245
LEU A 196
ILE A 237
 None
 0.87A 2q83A-2o2zA:
undetectable		 2q83A-2o2zA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 LEU A 123
PRO A 124
LEU A 168
 None
 0.47A 2qd5B-2o2zA:
3.1		 2qd5B-2o2zA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 5 LEU A 132
ASP A  37
ALA A  36
ILE A 148
 None
 1.15A 2qhfA-2o2zA:
undetectable		 2qhfA-2o2zA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 6 LEU A  19
GLY A  14
LEU A  64
SER A  65
 None
NAD  A 400 ( 3.2A)
None
None
 0.79A 3aiaA-2o2zA:
2.2		 3aiaA-2o2zA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 ASN A 302
HIS A 301
VAL A 218
 None
NAD  A 400 (-3.6A)
NAD  A 400 (-4.4A)
 0.85A 3elzB-2o2zA:
undetectable		 3elzB-2o2zA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 ARG A  78
ASP A  37
GLN A 221
 SO4  A 323 (-2.8A)
None
NAD  A 400 (-3.4A)
 0.91A 3lcvB-2o2zA:
3.0		 3lcvB-2o2zA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 ARG A  78
ASP A  56
GLN A 221
 SO4  A 323 (-2.8A)
SO4  A 324 ( 4.6A)
NAD  A 400 (-3.4A)
 0.92A 3lcvB-2o2zA:
3.0		 3lcvB-2o2zA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 8 ASP A  37
ASP A  56
GLY A  12
PRO A  54
 None
SO4  A 324 ( 4.6A)
SO4  A 324 (-2.6A)
None
 1.04A 3s3mA-2o2zA:
undetectable		 3s3mA-2o2zA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 8 ASP A  37
ASP A  56
GLY A  12
PRO A  54
 None
SO4  A 324 ( 4.6A)
SO4  A 324 (-2.6A)
None
 0.98A 3s3nA-2o2zA:
undetectable		 3s3nA-2o2zA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A 245
LEU A  15
VAL A 306
ILE A 175
ILE A   7
 None
 1.05A 3w67B-2o2zA:
undetectable		 3w67B-2o2zA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 9 LEU A 250
GLY A 184
VAL A 306
SER A 307
LEU A 311
 None
 0.90A 4qd3A-2o2zA:
undetectable		 4qd3A-2o2zA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		6 / 12 LEU A  19
ALA A  63
LEU A  61
VAL A  33
ALA A  31
ILE A 109
 None
 1.25A 4x20B-2o2zA:
4.8		 4x20B-2o2zA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 6 ALA A  36
ARG A 157
GLY A 134
GLU A 135
 None
 0.99A 5btgA-2o2zA:
undetectable
5btgB-2o2zA:
undetectable
5btgC-2o2zA:
undetectable		 5btgA-2o2zA:
22.07
5btgB-2o2zA:
23.20
5btgC-2o2zA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 PHE A   9
ILE A 181
ASP A 248
 None
 0.77A 5cswA-2o2zA:
undetectable		 5cswA-2o2zA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 ARG A  78
ASN A  92
ASP A  37
 SO4  A 323 (-2.8A)
SO4  A 323 (-3.5A)
None
 0.93A 5gwxA-2o2zA:
4.9		 5gwxA-2o2zA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 7 GLY A  43
SER A  89
LEU A  95
GLU A 145
 None
 0.88A 5izfA-2o2zA:
undetectable		 5izfA-2o2zA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 HIS A  88
ASN A  92
ALA A  96
 None
SO4  A 323 (-3.5A)
None
 0.81A 5n4tB-2o2zA:
undetectable		 5n4tB-2o2zA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 9 ILE A 175
LYS A 212
ILE A 310
LEU A 311
 None
 0.79A 5vkqB-2o2zA:
undetectable
5vkqC-2o2zA:
undetectable		 5vkqB-2o2zA:
11.23
5vkqC-2o2zA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 12 LEU A  93
GLY A  91
SER A 129
VAL A  35
ARG A  58
 None
None
None
None
SO4  A 323 (-3.8A)
 1.26A 6bxmA-2o2zA:
undetectable		 6bxmA-2o2zA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 12 LEU A  93
GLY A  91
VAL A  35
ARG A  58
ASP A  56
 None
None
None
SO4  A 323 (-3.8A)
SO4  A 324 ( 4.6A)
 1.06A 6bxnB-2o2zA:
undetectable		 6bxnB-2o2zA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 ARG A  78
PHE A  79
GLY A  87
 SO4  A 323 (-2.8A)
None
None
 0.77A 6fgdA-2o2zA:
2.5		 6fgdA-2o2zA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 2o2z HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 12 PRO A 167
VAL A  35
THR A  34
ILE A 130
PHE A   9
 None
 1.18A 6hlpA-2o2zA:
4.6		 6hlpA-2o2zA:
19.96