SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o34'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2o34 HYPOTHETICAL PROTEIN
(Desulfovibrio
vulgaris) 		5 / 11 ILE A 108
VAL A 112
ALA A 113
PHE A 116
LEU A  44
 None
 1.25A 1uduA-2o34A:
undetectable		 1uduA-2o34A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 2o34 HYPOTHETICAL PROTEIN
(Desulfovibrio
vulgaris) 		3 / 3 ALA A 199
GLY A 129
SER A 165
 NA  A 501 ( 4.8A)
NA  A 503 ( 4.2A)
None
 0.58A 2ivuA-2o34A:
undetectable		 2ivuA-2o34A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 2o34 HYPOTHETICAL PROTEIN
(Desulfovibrio
vulgaris) 		3 / 3 GLU A 245
ASP A 243
ASP A 138
 None
 0.75A 3jb2A-2o34A:
undetectable		 3jb2A-2o34A:
12.93