SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o36'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 5 GLU A 652
ALA A 486
SER A 484
HIS A 480
 None
 1.12A 1errA-2o36A:
undetectable
1errB-2o36A:
undetectable		 1errA-2o36A:
17.51
1errB-2o36A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 11 LEU A 295
LEU A 298
ALA A 299
LEU A 552
LEU A 579
 None
 1.07A 1g50A-2o36A:
undetectable		 1g50A-2o36A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 10 LEU A 295
LEU A 298
ALA A 299
LEU A 552
LEU A 579
 None
 1.20A 1gwrA-2o36A:
undetectable		 1gwrA-2o36A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 6 HIS A 223
LEU A 196
LEU A 199
PRO A 200
 None
 1.04A 1hz4A-2o36A:
undetectable		 1hz4A-2o36A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 THR A 470
HIS A 473
GLU A 474
HIS A 477
GLU A 502
 None
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
ZN  A 690 (-2.3A)
 0.44A 1j36A-2o36A:
18.4		 1j36A-2o36A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 THR A 470
HIS A 473
GLU A 474
HIS A 477
TYR A 612
 None
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
None
 0.99A 1j36A-2o36A:
18.4		 1j36A-2o36A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 THR A 470
HIS A 473
GLU A 474
HIS A 477
GLU A 502
 None
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
ZN  A 690 (-2.3A)
 0.45A 1j36B-2o36A:
17.7		 1j36B-2o36A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 THR A 470
HIS A 473
GLU A 474
HIS A 477
TYR A 612
 None
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
None
 0.99A 1j36B-2o36A:
17.7		 1j36B-2o36A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 11 GLU A 502
HIS A 473
GLU A 474
PHE A 428
TYR A 422
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
None
None
 1.30A 1j37A-2o36A:
18.2		 1j37A-2o36A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 11 GLU A 502
HIS A 473
GLU A 474
PHE A 428
TYR A 422
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
None
None
 1.30A 1j37B-2o36A:
17.9		 1j37B-2o36A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 GLU A 502
HIS A 473
GLU A 474
PHE A 428
TYR A 422
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
None
None
 1.31A 1o86A-2o36A:
18.5		 1o86A-2o36A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 1.03A 1v55C-2o36A:
4.3
1v55J-2o36A:
undetectable		 1v55C-2o36A:
17.45
1v55J-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 1.01A 1v55P-2o36A:
4.9
1v55W-2o36A:
undetectable		 1v55P-2o36A:
17.45
1v55W-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.88A 1v7zA-2o36A:
undetectable		 1v7zA-2o36A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.88A 1v7zB-2o36A:
undetectable		 1v7zB-2o36A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.89A 1v7zC-2o36A:
undetectable		 1v7zC-2o36A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.91A 1v7zD-2o36A:
undetectable		 1v7zD-2o36A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.90A 1v7zE-2o36A:
undetectable		 1v7zE-2o36A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.89A 1v7zF-2o36A:
undetectable		 1v7zF-2o36A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 425
HIS A 473
GLU A 474
HIS A 477
GLU A 502
 None
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
ZN  A 690 (-2.3A)
 0.55A 2c6nA-2o36A:
16.3		 2c6nA-2o36A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 425
HIS A 473
GLU A 474
HIS A 477
TYR A 612
 None
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
None
 1.24A 2c6nA-2o36A:
16.3		 2c6nA-2o36A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 0.93A 2dysC-2o36A:
4.9
2dysJ-2o36A:
undetectable		 2dysC-2o36A:
17.45
2dysJ-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 1.00A 2eijC-2o36A:
4.9
2eijJ-2o36A:
undetectable		 2eijC-2o36A:
17.45
2eijJ-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 0.98A 2eimC-2o36A:
3.5
2eimJ-2o36A:
undetectable		 2eimC-2o36A:
17.45
2eimJ-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 1.02A 2einC-2o36A:
3.4
2einJ-2o36A:
undetectable		 2einC-2o36A:
17.45
2einJ-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 6 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 1.00A 2einP-2o36A:
3.4
2einW-2o36A:
undetectable		 2einP-2o36A:
17.45
2einW-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 5 ASP A 102
LEU A 105
LYS A 104
ARG A  79
 None
 1.43A 2gj5A-2o36A:
undetectable		 2gj5A-2o36A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 THR A 470
HIS A 473
GLU A 474
HIS A 477
 None
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
 0.30A 2jihB-2o36A:
2.3		 2jihB-2o36A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 7 LEU A 376
LEU A 377
ARG A 647
GLU A 630
ARG A 626
 None
 1.43A 2jn3A-2o36A:
undetectable		 2jn3A-2o36A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 ARG A 333
GLN A 581
PRO A 587
 None
 1.01A 2qhfA-2o36A:
undetectable		 2qhfA-2o36A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 PHE A  84
VAL A 394
ALA A 447
ASP A 414
ARG A 418
 None
 1.39A 2qm9A-2o36A:
undetectable		 2qm9A-2o36A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 HIS A 473
GLU A 474
HIS A 477
GLU A 502
TYR A 612
 ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
ZN  A 690 (-2.3A)
None
 1.13A 2x91A-2o36A:
18.2		 2x91A-2o36A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLN A 562
GLN A 668
ASP A 296
TYR A 609
 None
 1.27A 2xz5C-2o36A:
undetectable
2xz5D-2o36A:
undetectable		 2xz5C-2o36A:
15.70
2xz5D-2o36A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 GLU A 111
ASP A 109
TYR A  75
 None
 0.55A 2yvlB-2o36A:
undetectable		 2yvlB-2o36A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 0.94A 2zxwC-2o36A:
2.8
2zxwJ-2o36A:
undetectable		 2zxwC-2o36A:
17.45
2zxwJ-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.89A 3a6jA-2o36A:
undetectable		 3a6jA-2o36A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.87A 3a6jB-2o36A:
undetectable		 3a6jB-2o36A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.87A 3a6jC-2o36A:
undetectable		 3a6jC-2o36A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.90A 3a6jE-2o36A:
undetectable		 3a6jE-2o36A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 502
HIS A 473
HIS A 477
GLU A 474
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 (-3.3A)
ZN  A 690 ( 4.1A)
 0.87A 3a6jF-2o36A:
undetectable		 3a6jF-2o36A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 6 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 0.97A 3ag1C-2o36A:
3.4
3ag1J-2o36A:
undetectable		 3ag1C-2o36A:
17.45
3ag1J-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 TYR A 609
HIS A 600
LEU A 280
VAL A 501
 None
 1.13A 3jwqC-2o36A:
undetectable		 3jwqC-2o36A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 HIS A 473
GLU A 474
HIS A 477
 ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
 0.19A 3kecB-2o36A:
3.5		 3kecB-2o36A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 GLY A 585
ILE A 555
VAL A 556
 None
 0.33A 3nv6A-2o36A:
2.4		 3nv6A-2o36A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_B_GLYB511_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 5 SER A 461
GLU A 467
LEU A 463
GLN A 464
LYS A 357
 None
 1.01A 3pgyB-2o36A:
0.0		 3pgyB-2o36A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 11 GLU A 502
HIS A 473
GLU A 474
PHE A 428
TYR A 422
 ZN  A 690 (-2.3A)
ZN  A 690 (-3.4A)
ZN  A 690 ( 4.1A)
None
None
 1.28A 4c2pA-2o36A:
18.7		 4c2pA-2o36A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 7 LEU A 564
GLN A 567
LEU A 601
PHE A 598
 None
 0.91A 5b1bP-2o36A:
4.7
5b1bW-2o36A:
undetectable		 5b1bP-2o36A:
17.45
5b1bW-2o36A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 THR A 527
SER A 529
TYR A 359
 None
 0.84A 5jsdA-2o36A:
undetectable		 5jsdA-2o36A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 THR A 527
SER A 529
TYR A 359
 None
 0.83A 5jsdB-2o36A:
undetectable		 5jsdB-2o36A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 THR A 527
SER A 529
TYR A 359
 None
 0.84A 5jsdC-2o36A:
undetectable		 5jsdC-2o36A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 THR A 527
SER A 529
TYR A 359
 None
 0.82A 5jseA-2o36A:
undetectable		 5jseA-2o36A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 THR A 527
SER A 529
TYR A 359
 None
 0.81A 5jseB-2o36A:
undetectable		 5jseB-2o36A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		3 / 3 THR A 527
SER A 529
TYR A 359
 None
 0.82A 5jseC-2o36A:
undetectable		 5jseC-2o36A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LI8_A_KKKA502_1
(PUTATIVE CYTOCHROME
P450 126)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		5 / 12 THR A 592
ASN A 183
ALA A 602
ARG A 247
ASN A 593
 None
 1.36A 5li8A-2o36A:
0.9		 5li8A-2o36A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 5 THR A 274
HIS A 275
ALA A 276
ASP A 277
 None
 1.44A 5mfxA-2o36A:
undetectable		 5mfxA-2o36A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 6 VAL A 556
ILE A 583
GLU A 582
ARG A 578
 None
 0.76A 5z3jA-2o36A:
undetectable		 5z3jA-2o36A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 2o36 THIMET
OLIGOPEPTIDASE
(Homo
sapiens) 		4 / 5 HIS A  87
GLU A 474
HIS A 477
VAL A 501
 None
ZN  A 690 ( 4.1A)
ZN  A 690 (-3.3A)
None
 1.14A 6bc9A-2o36A:
undetectable		 6bc9A-2o36A:
9.57