SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 2o39 FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 ASN A 144
ALA A 143
LYS A 157
 None
 1.04A 3runA-2o39A:
undetectable		 3runA-2o39A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2o39 FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 PHE A 199
ILE A 229
GLY A 234
ALA A 171
ILE A 290
 None
 1.06A 4nkxC-2o39A:
undetectable		 4nkxC-2o39A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2o39 FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 PHE A 199
ILE A 229
GLY A 234
ALA A 171
ILE A 290
 None
 1.04A 4nkxD-2o39A:
undetectable		 4nkxD-2o39A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 2o39 FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 4 THR A 239
GLY A 234
ASP A 325
SER A 238
 None
 1.35A 4rfqA-2o39A:
undetectable		 4rfqA-2o39A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2o39 FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 6 ILE A 290
LEU A 197
PHE A 199
ARG A 322
 None
 1.02A 5b1aN-2o39A:
undetectable
5b1aW-2o39A:
undetectable		 5b1aN-2o39A:
16.86
5b1aW-2o39A:
15.79