SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o3f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2o3f PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YBBH
(Bacillus
subtilis) 		4 / 6 VAL A  72
ARG A  71
LEU A  68
LEU A  60
 MLY  A  69 ( 4.0A)
None
MLY  A  69 ( 3.6A)
None
 0.80A 3kp6A-2o3fA:
1.4
3kp6B-2o3fA:
1.8		 3kp6A-2o3fA:
23.65
3kp6B-2o3fA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 2o3f PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YBBH
(Bacillus
subtilis) 		4 / 7 VAL A  72
LEU A   6
PHE A  65
LEU A  56
 MLY  A  69 ( 4.0A)
None
MLY  A  69 (-3.9A)
None
 0.99A 3qeoB-2o3fA:
undetectable		 3qeoB-2o3fA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2o3f PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YBBH
(Bacillus
subtilis) 		3 / 3 HIS A  32
SER A  37
GLU A  36
 SO4  A 203 (-3.8A)
MLY  A  33 ( 2.7A)
MLY  A  33 ( 4.3A)
 0.93A 3s8pA-2o3fA:
undetectable		 3s8pA-2o3fA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2o3f PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YBBH
(Bacillus
subtilis) 		4 / 7 ILE A   9
LEU A   6
GLY A   4
GLY A   5
 None
 0.85A 5a06B-2o3fA:
undetectable		 5a06B-2o3fA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2o3f PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YBBH
(Bacillus
subtilis) 		4 / 7 ILE A   9
LEU A   6
GLY A   4
GLY A   5
 None
 0.86A 5a06F-2o3fA:
undetectable		 5a06F-2o3fA:
16.51