SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_D_BEZD2002_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)
2o3g PUTATIVE PROTEIN
(Neisseria
meningitidis)
5 / 9 PHE A 236
LEU A 214
PHE A 208
GLN A 202
LEU A 193
None
1.37A 2ok6B-2o3gA:
1.3
2ok6D-2o3gA:
0.0
2ok6B-2o3gA:
13.93
2ok6D-2o3gA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_H_BEZH2001_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)
2o3g PUTATIVE PROTEIN
(Neisseria
meningitidis)
5 / 10 PHE A 236
LEU A 214
PHE A 208
GLN A 202
LEU A 193
None
1.36A 2ok6A-2o3gA:
1.3
2ok6H-2o3gA:
undetectable
2ok6A-2o3gA:
13.93
2ok6H-2o3gA:
17.19