SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o3i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 6 PHE A 332
LEU A 236
VAL A 241
VAL A 324
 None
 0.77A 1e7aB-2o3iA:
undetectable		 1e7aB-2o3iA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 7 LEU A  10
THR A  46
TYR A  44
LYS A  40
 None
 1.21A 1rmtB-2o3iA:
undetectable		 1rmtB-2o3iA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 10 ALA A  86
LEU A 158
MET A  68
GLY A  69
PHE A 203
 None
 1.43A 1uhoA-2o3iA:
undetectable		 1uhoA-2o3iA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 SER A  30
ALA A 111
GLY A  25
LEU A 112
PRO A  71
 None
 1.27A 1vpoH-2o3iA:
undetectable
1vpoL-2o3iA:
undetectable		 1vpoH-2o3iA:
18.66
1vpoL-2o3iA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 LEU A 141
ILE A 183
VAL A 170
LEU A 195
MET A  68
 None
 1.02A 2g78A-2o3iA:
undetectable		 2g78A-2o3iA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 6 PRO A  80
HIS A  33
ASP A  72
TYR A  67
 None
 1.44A 2lh8A-2o3iA:
undetectable		 2lh8A-2o3iA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 9 ILE A 257
LEU A 364
ARG A 136
GLY A 135
ALA A 134
 None
 1.49A 2xfsB-2o3iA:
undetectable		 2xfsB-2o3iA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 ALA A 156
LEU A 206
GLN A 189
VAL A 166
THR A 154
 None
 1.20A 3ix9A-2o3iA:
undetectable		 3ix9A-2o3iA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 6 SER A 118
PHE A 114
ASP A 130
PRO A 107
 None
 1.35A 3jqaB-2o3iA:
undetectable		 3jqaB-2o3iA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 8 LEU A 364
SER A 365
LEU A 302
ILE A 369
PHE A 373
 None
 1.36A 3ln1A-2o3iA:
undetectable		 3ln1A-2o3iA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 7 LEU A 364
SER A 365
LEU A 302
ILE A 369
PHE A 373
 None
 1.35A 3ln1B-2o3iA:
undetectable		 3ln1B-2o3iA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		6 / 12 GLY A 113
VAL A  65
ALA A 121
ALA A 122
LEU A  14
LEU A 119
 None
 1.50A 3mteB-2o3iA:
undetectable		 3mteB-2o3iA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 GLY A  24
GLU A 300
GLY A 135
ALA A 106
ASP A 130
 None
 1.20A 3qowA-2o3iA:
undetectable		 3qowA-2o3iA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 VAL A 138
ALA A 137
GLY A  24
ALA A 229
LEU A 364
 None
 1.21A 3qxyA-2o3iA:
undetectable		 3qxyA-2o3iA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 11 VAL A 138
ALA A 137
GLY A  24
ALA A 229
LEU A 364
 None
 1.25A 3rc0A-2o3iA:
undetectable		 3rc0A-2o3iA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 11 VAL A 187
LEU A 191
GLU A 167
ALA A 156
VAL A 170
 None
 1.04A 4e0fA-2o3iA:
undetectable		 4e0fA-2o3iA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 6 ARG A 136
GLY A 135
GLU A 108
MET A 247
 None
 1.21A 4g0vB-2o3iA:
undetectable		 4g0vB-2o3iA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 8 LEU A 206
ALA A 156
LEU A 158
VAL A 170
 None
 0.89A 4iizB-2o3iA:
undetectable		 4iizB-2o3iA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 7 MET A  64
LEU A 158
ALA A 156
THR A 154
 None
 0.90A 4ik7A-2o3iA:
undetectable		 4ik7A-2o3iA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 PHE A  19
LEU A 255
PHE A 250
PHE A  20
GLY A  16
 None
 1.36A 4pevC-2o3iA:
undetectable		 4pevC-2o3iA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 8 VAL A  77
PHE A 203
GLY A 204
ALA A 159
GLY A 160
 None
 1.43A 4zjzB-2o3iA:
undetectable		 4zjzB-2o3iA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 ALA A 137
PRO A 139
GLY A  26
GLY A  24
LEU A 112
 None
 0.99A 5c0oG-2o3iA:
undetectable		 5c0oG-2o3iA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 GLY A 205
GLY A  82
GLY A 163
LEU A 164
ALA A  66
 None
 0.98A 5c0oG-2o3iA:
undetectable		 5c0oG-2o3iA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 ALA A 134
PRO A 139
GLY A  24
SER A 333
THR A  27
 None
 1.01A 5hfjB-2o3iA:
undetectable		 5hfjB-2o3iA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 5 LEU A 303
TYR A 297
LYS A 282
LEU A 380
 None
 1.47A 5ki6A-2o3iA:
undetectable		 5ki6A-2o3iA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 8 SER A 301
SER A  22
ALA A 314
ASP A 318
 None
 1.11A 5l5fY-2o3iA:
undetectable
5l5fZ-2o3iA:
undetectable		 5l5fY-2o3iA:
20.92
5l5fZ-2o3iA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 10 GLN A 329
LEU A 112
GLY A 110
GLY A  21
ALA A  31
 None
 1.18A 5o96E-2o3iA:
undetectable
5o96F-2o3iA:
undetectable		 5o96E-2o3iA:
23.43
5o96F-2o3iA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 2o3i HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 LEU A 255
LEU A 251
GLY A 233
GLY A  16
GLY A 110
 None
 0.95A 6ce2B-2o3iA:
undetectable		 6ce2B-2o3iA:
14.68