SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o4j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 TYR A 143
LEU A 226
LEU A 229
VAL A 230
SER A 233
SER A 271
SER A 274
CYH A 284
VAL A 296
HIS A 301
LEU A 305
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.5A)
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
None
VD4  A 500 ( 3.9A)
 0.30A 1db1A-2o4jA:
38.4		 1db1A-2o4jA:
90.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		6 / 6 LEU A 223
ILE A 267
ARG A 270
TRP A 282
TYR A 291
VAL A 414
 None
VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.7A)
None
None
 0.18A 1db1A-2o4jA:
38.4		 1db1A-2o4jA:
90.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		5 / 9 THR A 358
LEU A 328
VAL A 327
ILE A 244
ILE A 134
 None
 1.34A 1gebA-2o4jA:
undetectable		 1gebA-2o4jA:
20.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		7 / 12 LEU A 229
VAL A 230
SER A 271
SER A 274
CYH A 284
LEU A 309
HIS A 301
 VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.4A)
None
VD4  A 500 ( 3.9A)
 1.39A 1ie9A-2o4jA:
39.3		 1ie9A-2o4jA:
90.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 TYR A 143
LEU A 226
LEU A 229
VAL A 230
SER A 233
SER A 271
SER A 274
CYH A 284
VAL A 296
HIS A 301
LEU A 309
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.5A)
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
None
VD4  A 500 ( 3.9A)
 0.29A 1ie9A-2o4jA:
39.3		 1ie9A-2o4jA:
90.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IE9_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		4 / 4 LEU A 223
ILE A 267
ARG A 270
TRP A 282
 None
VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.7A)
 0.29A 1ie9A-2o4jA:
39.3		 1ie9A-2o4jA:
90.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		6 / 12 LEU A 229
SER A 233
SER A 274
TRP A 282
CYH A 284
LEU A 389
 VD4  A 500 ( 4.8A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.7A)
VD4  A 500 ( 3.4A)
None
 1.41A 1rk3A-2o4jA:
41.9		 1rk3A-2o4jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 TYR A 143
LEU A 229
VAL A 230
SER A 233
SER A 271
SER A 274
TRP A 282
CYH A 284
VAL A 296
HIS A 301
LEU A 305
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.7A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
None
VD4  A 500 ( 3.9A)
 0.12A 1rk3A-2o4jA:
41.9		 1rk3A-2o4jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		4 / 4 LEU A 223
ILE A 267
ARG A 270
TYR A 397
 None
VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.0A)
None
 0.18A 1rk3A-2o4jA:
41.9		 1rk3A-2o4jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 LEU A 223
LEU A 229
VAL A 230
ILE A 267
SER A 271
SER A 274
TRP A 282
CYH A 284
TYR A 291
VAL A 296
LEU A 305
LEU A 309
 None
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 4.7A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.7A)
VD4  A 500 ( 3.4A)
None
VD4  A 500 ( 4.4A)
None
None
 0.28A 1s19A-2o4jA:
38.8		 1s19A-2o4jA:
89.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		5 / 5 TYR A 143
SER A 233
ARG A 270
HIS A 301
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 3.9A)
 0.16A 1s19A-2o4jA:
38.8		 1s19A-2o4jA:
89.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		5 / 12 THR A 302
LEU A 305
ILE A 306
VAL A 293
LEU A 389
 None
 1.29A 1wsvB-2o4jA:
undetectable		 1wsvB-2o4jA:
21.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		6 / 12 PHE A 150
LEU A 229
SER A 233
SER A 274
CYH A 284
LEU A 389
 None
VD4  A 500 ( 4.8A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.4A)
None
 1.28A 2hc4A-2o4jA:
39.3		 2hc4A-2o4jA:
63.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		8 / 12 PHE A 153
LEU A 229
VAL A 230
SER A 233
VAL A 296
HIS A 301
LEU A 305
HIS A 393
 None
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
None
VD4  A 500 ( 3.9A)
 1.40A 2hc4A-2o4jA:
39.3		 2hc4A-2o4jA:
63.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 TYR A 143
PHE A 150
LEU A 229
VAL A 230
SER A 233
SER A 274
CYH A 284
VAL A 296
HIS A 301
LEU A 305
HIS A 393
LEU A 400
 VD4  A 500 ( 4.7A)
None
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
None
VD4  A 500 ( 3.9A)
VD4  A 500 ( 4.9A)
 0.32A 2hc4A-2o4jA:
39.3		 2hc4A-2o4jA:
63.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		7 / 7 LEU A 223
LEU A 226
ILE A 267
ARG A 270
SER A 271
TRP A 282
TYR A 397
 None
VD4  A 500 ( 4.5A)
VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 3.7A)
None
 0.24A 2hc4A-2o4jA:
39.3		 2hc4A-2o4jA:
63.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		3 / 3 HIS A 130
ILE A 132
LEU A 355
 None
 0.72A 2kceA-2o4jA:
undetectable		 2kceA-2o4jA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		3 / 3 ASP A 149
THR A 411
PRO A 412
 None
 0.71A 2pynB-2o4jA:
undetectable		 2pynB-2o4jA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		4 / 8 LEU A 135
ILE A 244
THR A 358
LEU A 328
 None
 0.78A 2xfhA-2o4jA:
undetectable		 2xfhA-2o4jA:
21.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		5 / 12 LEU A 229
SER A 233
SER A 274
CYH A 284
LEU A 389
 VD4  A 500 ( 4.8A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.4A)
None
 1.27A 2zlcA-2o4jA:
41.7		 2zlcA-2o4jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		5 / 12 LEU A 229
SER A 271
SER A 274
HIS A 301
LEU A 220
 VD4  A 500 ( 4.8A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.9A)
None
 1.33A 2zlcA-2o4jA:
41.7		 2zlcA-2o4jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 TYR A 143
LEU A 229
VAL A 230
SER A 233
SER A 271
SER A 274
CYH A 284
VAL A 296
HIS A 301
LEU A 305
HIS A 393
LEU A 400
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
None
VD4  A 500 ( 3.9A)
VD4  A 500 ( 4.9A)
 0.32A 2zlcA-2o4jA:
41.7		 2zlcA-2o4jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		5 / 5 LEU A 223
ILE A 267
ARG A 270
TRP A 282
TYR A 397
 None
VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.7A)
None
 0.13A 2zlcA-2o4jA:
41.7		 2zlcA-2o4jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		5 / 12 LEU A 226
VAL A 230
SER A 233
VAL A 296
LEU A 309
 VD4  A 500 ( 4.5A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 4.4A)
None
 1.18A 3m7rA-2o4jA:
38.9		 3m7rA-2o4jA:
88.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		10 / 12 TYR A 143
LEU A 226
LEU A 229
VAL A 230
SER A 271
SER A 274
CYH A 284
VAL A 296
LEU A 305
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.5A)
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 4.4A)
None
VD4  A 500 ( 3.9A)
 0.29A 3m7rA-2o4jA:
38.9		 3m7rA-2o4jA:
88.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		10 / 12 TYR A 143
LEU A 226
VAL A 230
SER A 233
SER A 271
SER A 274
CYH A 284
VAL A 296
LEU A 305
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.5A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 4.4A)
None
VD4  A 500 ( 3.9A)
 0.60A 3m7rA-2o4jA:
38.9		 3m7rA-2o4jA:
88.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M7R_A_VDXA425_2
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		9 / 9 PHE A 150
LEU A 223
ILE A 267
ARG A 270
TRP A 282
TYR A 291
LEU A 309
TYR A 397
VAL A 414
 None
None
VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.7A)
None
None
None
None
 0.29A 3m7rA-2o4jA:
38.9		 3m7rA-2o4jA:
88.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		3 / 3 ASP A 149
THR A 411
PRO A 412
 None
 0.66A 3tkgD-2o4jA:
undetectable		 3tkgD-2o4jA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		5 / 9 LEU A 383
LEU A 329
ILE A 244
ILE A 351
GLN A 352
 None
 1.09A 3tmzA-2o4jA:
undetectable		 3tmzA-2o4jA:
21.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		6 / 12 LEU A 229
SER A 233
SER A 274
TRP A 282
CYH A 284
LEU A 389
 VD4  A 500 ( 4.8A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.7A)
VD4  A 500 ( 3.4A)
None
 1.42A 3vt3A-2o4jA:
40.9		 3vt3A-2o4jA:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 TYR A 143
LEU A 229
VAL A 230
SER A 233
SER A 271
SER A 274
TRP A 282
CYH A 284
VAL A 296
HIS A 301
LEU A 305
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.7A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
None
VD4  A 500 ( 3.9A)
 0.15A 3vt3A-2o4jA:
40.9		 3vt3A-2o4jA:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 TYR A 143
TYR A 147
LEU A 229
VAL A 230
SER A 233
ARG A 270
SER A 271
SER A 274
VAL A 296
HIS A 301
LEU A 305
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.9A)
VD4  A 500 ( 4.8A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
None
VD4  A 500 ( 3.9A)
 0.58A 3vt7A-2o4jA:
39.4		 3vt7A-2o4jA:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		4 / 4 LEU A 223
ILE A 267
TYR A 291
TYR A 397
 None
VD4  A 500 ( 4.7A)
None
None
 0.12A 3vt7A-2o4jA:
39.4		 3vt7A-2o4jA:
99.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		5 / 12 ALA A 331
TYR A 376
SER A 356
LEU A 359
LEU A 321
 None
 1.42A 4qztC-2o4jA:
undetectable		 4qztC-2o4jA:
17.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 TYR A 143
VAL A 230
SER A 233
ILE A 267
ARG A 270
SER A 271
SER A 274
TRP A 282
CYH A 284
VAL A 296
HIS A 301
HIS A 393
 VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.6A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.7A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 3.9A)
 0.28A 4rujA-2o4jA:
39.0		 4rujA-2o4jA:
62.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		6 / 12 VAL A 230
SER A 271
SER A 274
TRP A 282
CYH A 284
HIS A 301
 VD4  A 500 ( 4.6A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.7A)
VD4  A 500 ( 3.4A)
VD4  A 500 ( 3.9A)
 1.31A 4rujA-2o4jA:
39.0		 4rujA-2o4jA:
62.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		4 / 8 LEU A 250
ILE A 244
ARG A 354
LEU A 355
 None
 0.83A 4zvcA-2o4jA:
1.1
4zvcB-2o4jA:
2.4		 4zvcA-2o4jA:
20.82
4zvcB-2o4jA:
20.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		8 / 12 PHE A 153
LEU A 229
SER A 233
ILE A 267
ARG A 270
VAL A 296
HIS A 301
HIS A 393
 None
VD4  A 500 ( 4.8A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 3.9A)
 1.34A 5h1eA-2o4jA:
39.6		 5h1eA-2o4jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		12 / 12 TYR A 143
PHE A 150
LEU A 229
SER A 233
ILE A 267
ARG A 270
SER A 271
SER A 274
TRP A 282
VAL A 296
HIS A 301
HIS A 393
 VD4  A 500 ( 4.7A)
None
VD4  A 500 ( 4.8A)
VD4  A 500 ( 2.8A)
VD4  A 500 ( 4.7A)
VD4  A 500 ( 4.0A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.7A)
VD4  A 500 ( 4.4A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 3.9A)
 0.27A 5h1eA-2o4jA:
39.6		 5h1eA-2o4jA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 2o4j VITAMIN D3 RECEPTOR
(Rattus
norvegicus) 		7 / 12 TYR A 143
PHE A 150
LEU A 229
SER A 271
SER A 274
TRP A 282
HIS A 301
 VD4  A 500 ( 4.7A)
None
VD4  A 500 ( 4.8A)
VD4  A 500 ( 3.9A)
VD4  A 500 ( 2.9A)
VD4  A 500 ( 3.7A)
VD4  A 500 ( 3.9A)
 1.21A 5h1eA-2o4jA:
39.6		 5h1eA-2o4jA:
100.00